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Q31EL5 (UPPP_THICR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:Tcr_1816
OrganismThiomicrospira crunogena (strain XCL-2) [Complete proteome] [HAMAP]
Taxonomic identifier317025 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaThiotrichalesPiscirickettsiaceaeThiomicrospira

Protein attributes

Sequence length255 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 255255Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000250278

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane41 – 6121Helical; Potential
Transmembrane70 – 9021Helical; Potential
Transmembrane97 – 11721Helical; Potential
Transmembrane139 – 15921Helical; Potential
Transmembrane175 – 19521Helical; Potential
Transmembrane208 – 22821Helical; Potential
Transmembrane234 – 25421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q31EL5 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: 7E81D805A75C418E

FASTA25528,758
        10         20         30         40         50         60 
MEIFQAAILG IIEGLTEFLP ISSTGHLIVV SDWLGIEQTK QNTAFEVIIQ VAAILAIFSH 

        70         80         90        100        110        120 
YKEKFSLQHL RLWNNVLIAF LPIAIIGFIF QDTVKAFFTI ETVAWFFIIG GLIFLIMEKL 

       130        140        150        160        170        180 
YVDGKHRTQD IEDLTMRQAF WIGIIQVFAL IPGTSRAGAS IVGGVMMGLD RKTAAEFSFL 

       190        200        210        220        230        240 
LALPVLMAAS GLDLLKHYED FNNTSWTPLM VGFLMAFLAA WLTIKVFIKF LQTFTFNAFG 

       250 
VYRIVFGIVL LIWFV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000109 Genomic DNA. Translation: ABB42408.1.
RefSeqYP_392082.1. NC_007520.2.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING317025.Tcr_1816.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABB42408; ABB42408; Tcr_1816.
GeneID3761388.
KEGGtcx:Tcr_1816.
PATRIC23975728. VBIThiCru83387_1893.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAMEIGTIF.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycTCRU317025:GHE8-1866-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_THICR
AccessionPrimary (citable) accession number: Q31EL5
Entry history
Integrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: December 6, 2005
Last modified: May 14, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families