Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q31ED4

- ARGB_THICR

UniProt

Q31ED4 - ARGB_THICR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Acetylglutamate kinase

Gene

argB

Organism
Thiomicrospira crunogena (strain XCL-2)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei33 – 331Transition state stabilizerUniRule annotation
Binding sitei90 – 901SubstrateUniRule annotation
Binding sitei195 – 1951SubstrateUniRule annotation
Sitei255 – 2551Transition state stabilizerUniRule annotation

GO - Molecular functioni

  1. acetylglutamate kinase activity Source: UniProtKB-EC
  2. ATP binding Source: UniProtKB-KW
  3. glutamate 5-kinase activity Source: InterPro

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-UniPathway
  2. proline biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTCRU317025:GHE8-1949-MONOMER.
UniPathwayiUPA00068; UER00107.

Names & Taxonomyi

Protein namesi
Recommended name:
Acetylglutamate kinaseUniRule annotation (EC:2.7.2.8UniRule annotation)
Alternative name(s):
N-acetyl-L-glutamate 5-phosphotransferaseUniRule annotation
NAG kinaseUniRule annotation
Short name:
AGKUniRule annotation
Gene namesi
Name:argBUniRule annotation
Ordered Locus Names:Tcr_1899
OrganismiThiomicrospira crunogena (strain XCL-2)
Taxonomic identifieri317025 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesPiscirickettsiaceaeThiomicrospira
ProteomesiUP000002713: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 298298Acetylglutamate kinasePRO_0000264781Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi317025.Tcr_1899.

Structurei

3D structure databases

ProteinModelPortaliQ31ED4.
SMRiQ31ED4. Positions 3-297.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni68 – 692Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the acetylglutamate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0548.
HOGENOMiHOG000233259.
KOiK00930.
OrthoDBiEOG6T1WVF.

Family and domain databases

Gene3Di3.40.1160.10. 1 hit.
HAMAPiMF_00082_A. ArgB_A.
MF_00082_B. ArgB_B.
InterProiIPR004662. AcgluKinase.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
[Graphical view]
PfamiPF00696. AA_kinase. 1 hit.
[Graphical view]
PIRSFiPIRSF000728. NAGK. 1 hit.
PRINTSiPR00474. GLU5KINASE.
SUPFAMiSSF53633. SSF53633. 1 hit.
TIGRFAMsiTIGR00761. argB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q31ED4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNLNKAQAQN IASVLAEALP YIQRFSGKTI VVKYGGNAMT EEALKNGFAR
60 70 80 90 100
DIVLMKLVGM NPVVVHGGGP QIGHLLERVG KQSEFIQGMR VTDSETMDIV
110 120 130 140 150
EMVLGGMVNK EIVNLIHQHN GNAVGLTGKD GNLIRAKKME MTAFNEDLNA
160 170 180 190 200
PELIDLGHVG EVERINTKVL DMLIQDDFIP VIAPVGVDEQ GHSYNINADL
210 220 230 240 250
VAGKVAEALH AEKLMLLTNT PGLLDKQGEL LTGLNAESVA ALIEDGTIYG
260 270 280 290
GMLPKIQCAL DAVQNGVESS HIIDGRVEHA VMLEVFTDEG VGTLITSH
Length:298
Mass (Da):31,990
Last modified:December 12, 2006 - v2
Checksum:i51A7B4456EBAE057
GO

Sequence cautioni

The sequence ABB42489.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000109 Genomic DNA. Translation: ABB42489.1. Different initiation.
RefSeqiYP_392163.1. NC_007520.2.

Genome annotation databases

EnsemblBacteriaiABB42489; ABB42489; Tcr_1899.
GeneIDi3761093.
KEGGitcx:Tcr_1899.
PATRICi23975902. VBIThiCru83387_1979.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000109 Genomic DNA. Translation: ABB42489.1 . Different initiation.
RefSeqi YP_392163.1. NC_007520.2.

3D structure databases

ProteinModelPortali Q31ED4.
SMRi Q31ED4. Positions 3-297.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 317025.Tcr_1899.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABB42489 ; ABB42489 ; Tcr_1899 .
GeneIDi 3761093.
KEGGi tcx:Tcr_1899.
PATRICi 23975902. VBIThiCru83387_1979.

Phylogenomic databases

eggNOGi COG0548.
HOGENOMi HOG000233259.
KOi K00930.
OrthoDBi EOG6T1WVF.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00107 .
BioCyci TCRU317025:GHE8-1949-MONOMER.

Family and domain databases

Gene3Di 3.40.1160.10. 1 hit.
HAMAPi MF_00082_A. ArgB_A.
MF_00082_B. ArgB_B.
InterProi IPR004662. AcgluKinase.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
[Graphical view ]
Pfami PF00696. AA_kinase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000728. NAGK. 1 hit.
PRINTSi PR00474. GLU5KINASE.
SUPFAMi SSF53633. SSF53633. 1 hit.
TIGRFAMsi TIGR00761. argB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: XCL-2.

Entry informationi

Entry nameiARGB_THICR
AccessioniPrimary (citable) accession number: Q31ED4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: December 12, 2006
Last modified: October 29, 2014
This is version 65 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3