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Q31ED4

- ARGB_THICR

UniProt

Q31ED4 - ARGB_THICR

Protein

Acetylglutamate kinase

Gene

argB

Organism
Thiomicrospira crunogena (strain XCL-2)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 2 (12 Dec 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei33 – 331Transition state stabilizerUniRule annotation
    Binding sitei90 – 901SubstrateUniRule annotation
    Binding sitei195 – 1951SubstrateUniRule annotation
    Sitei255 – 2551Transition state stabilizerUniRule annotation

    GO - Molecular functioni

    1. acetylglutamate kinase activity Source: UniProtKB-EC
    2. ATP binding Source: UniProtKB-KW
    3. glutamate 5-kinase activity Source: InterPro

    GO - Biological processi

    1. arginine biosynthetic process Source: UniProtKB-UniPathway
    2. proline biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Amino-acid biosynthesis, Arginine biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciTCRU317025:GHE8-1949-MONOMER.
    UniPathwayiUPA00068; UER00107.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acetylglutamate kinaseUniRule annotation (EC:2.7.2.8UniRule annotation)
    Alternative name(s):
    N-acetyl-L-glutamate 5-phosphotransferaseUniRule annotation
    NAG kinaseUniRule annotation
    Short name:
    AGKUniRule annotation
    Gene namesi
    Name:argBUniRule annotation
    Ordered Locus Names:Tcr_1899
    OrganismiThiomicrospira crunogena (strain XCL-2)
    Taxonomic identifieri317025 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesPiscirickettsiaceaeThiomicrospira
    ProteomesiUP000002713: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 298298Acetylglutamate kinasePRO_0000264781Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi317025.Tcr_1899.

    Structurei

    3D structure databases

    ProteinModelPortaliQ31ED4.
    SMRiQ31ED4. Positions 3-297.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni68 – 692Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the acetylglutamate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0548.
    HOGENOMiHOG000233259.
    KOiK00930.
    OrthoDBiEOG6T1WVF.

    Family and domain databases

    Gene3Di3.40.1160.10. 1 hit.
    HAMAPiMF_00082_A. ArgB_A.
    MF_00082_B. ArgB_B.
    InterProiIPR004662. AcgluKinase.
    IPR001048. Asp/Glu/Uridylate_kinase.
    IPR001057. Glu/AcGlu_kinase.
    [Graphical view]
    PfamiPF00696. AA_kinase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000728. NAGK. 1 hit.
    PRINTSiPR00474. GLU5KINASE.
    SUPFAMiSSF53633. SSF53633. 1 hit.
    TIGRFAMsiTIGR00761. argB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q31ED4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNLNKAQAQN IASVLAEALP YIQRFSGKTI VVKYGGNAMT EEALKNGFAR    50
    DIVLMKLVGM NPVVVHGGGP QIGHLLERVG KQSEFIQGMR VTDSETMDIV 100
    EMVLGGMVNK EIVNLIHQHN GNAVGLTGKD GNLIRAKKME MTAFNEDLNA 150
    PELIDLGHVG EVERINTKVL DMLIQDDFIP VIAPVGVDEQ GHSYNINADL 200
    VAGKVAEALH AEKLMLLTNT PGLLDKQGEL LTGLNAESVA ALIEDGTIYG 250
    GMLPKIQCAL DAVQNGVESS HIIDGRVEHA VMLEVFTDEG VGTLITSH 298
    Length:298
    Mass (Da):31,990
    Last modified:December 12, 2006 - v2
    Checksum:i51A7B4456EBAE057
    GO

    Sequence cautioni

    The sequence ABB42489.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000109 Genomic DNA. Translation: ABB42489.1. Different initiation.
    RefSeqiYP_392163.1. NC_007520.2.

    Genome annotation databases

    EnsemblBacteriaiABB42489; ABB42489; Tcr_1899.
    GeneIDi3761093.
    KEGGitcx:Tcr_1899.
    PATRICi23975902. VBIThiCru83387_1979.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000109 Genomic DNA. Translation: ABB42489.1 . Different initiation.
    RefSeqi YP_392163.1. NC_007520.2.

    3D structure databases

    ProteinModelPortali Q31ED4.
    SMRi Q31ED4. Positions 3-297.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 317025.Tcr_1899.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABB42489 ; ABB42489 ; Tcr_1899 .
    GeneIDi 3761093.
    KEGGi tcx:Tcr_1899.
    PATRICi 23975902. VBIThiCru83387_1979.

    Phylogenomic databases

    eggNOGi COG0548.
    HOGENOMi HOG000233259.
    KOi K00930.
    OrthoDBi EOG6T1WVF.

    Enzyme and pathway databases

    UniPathwayi UPA00068 ; UER00107 .
    BioCyci TCRU317025:GHE8-1949-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1160.10. 1 hit.
    HAMAPi MF_00082_A. ArgB_A.
    MF_00082_B. ArgB_B.
    InterProi IPR004662. AcgluKinase.
    IPR001048. Asp/Glu/Uridylate_kinase.
    IPR001057. Glu/AcGlu_kinase.
    [Graphical view ]
    Pfami PF00696. AA_kinase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000728. NAGK. 1 hit.
    PRINTSi PR00474. GLU5KINASE.
    SUPFAMi SSF53633. SSF53633. 1 hit.
    TIGRFAMsi TIGR00761. argB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: XCL-2.

    Entry informationi

    Entry nameiARGB_THICR
    AccessioniPrimary (citable) accession number: Q31ED4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 12, 2006
    Last sequence update: December 12, 2006
    Last modified: October 1, 2014
    This is version 64 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3