Q31DI7 (Q31DI7_THICR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component HAMAP MF_00227
Short name=RNase P protein HAMAP MF_00227
Short name=RNaseP protein HAMAP MF_00227
EC=3.1.26.5 HAMAP MF_00227

Alternative name(s):
Protein C5 HAMAP MF_00227

Gene names

Name:	rnpA HAMAP MF_00227
Ordered Locus Names:	Tcr_2198

Organism

Thiomicrospira crunogena (strain XCL-2) [Complete proteome] [HAMAP]

Taxonomic identifier

317025 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Thiotrichales › Piscirickettsiaceae › Thiomicrospira

Protein attributes

Sequence length	162 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme By similarity. HAMAP MF_00227 SAAS SAAS000100
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00227 SAAS SAAS000100
Subunit structure	Consists of a catalytic RNA component (M1 or RnpB) and a protein subunit By similarity. SAAS SAAS000100 Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit By similarity. HAMAP MF_00227
Sequence similarities	Belongs to the RnpA family. HAMAP MF_00227

Ontologies

Keywords
Biological process	tRNA processing HAMAP MF_00227 SAAS SAAS000100
Ligand	RNA-binding HAMAP MF_00227 SAAS SAAS000100
Molecular function	Endonuclease HAMAP MF_00227 SAAS SAAS000100 Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP tRNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q31DI7 [UniParc]. Last modified December 6, 2005. Version 1. Checksum: A6AC88627C2BE475	FASTA	162	18,827
	10 20 30 40 50 60 MINNTHQNSD GELSSLSLDE LELPHQDFSR NHFPKSLRLL SPQDFQFVFA RAEKFSNRHW 70 80 90 100 110 120 TFIVRPNDKS YPRLGLAIAK KQLAKSVWRN RVKRLARETF RQHKQALSGY DIVVLGRRGM 130 140 150 160 QDVDNETLIK SFEHLIRKIQ KSGLKDGQPM TNTKKSPTKG LK

References

[1]

"The genome of deep-sea vent chemolithoautotroph Thiomicrospira crunogena XCL-2." Scott K.M., Sievert S.M., Abril F.N., Ball L.A., Barrett C.J., Blake R.A., Boller A.J., Chain P.S.G., Clark J.A., Davis C.R., Detter C., Do K.F., Dobrinski K.P., Faza B.I., Fitzpatrick K.A., Freyermuth S.K., Harmer T.L., Hauser L.J. , Huegler M., Kerfeld C.A., Klotz M.G., Kong W.W., Land M., Lapidus A., Larimer F.W., Longo D.L., Lucas S., Malfatti S.A., Massey S.E., Martin D.D., McCuddin Z., Meyer F., Moore J.L., Ocampo L.H. Jr., Paul J.H., Paulsen I.T., Reep D.K., Ren Q., Ross R.L., Sato P.Y., Thomas P., Tinkham L.E., Zeruth G.T. PLoS Biol. 4:1-17(2006) [PubMed: 17105352] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000109 Genomic DNA. Translation: ABB42786.1.
RefSeq	YP_392460.1. NC_007520.2.
3D structure databases
ProteinModelPortal	Q31DI7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q31DI7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3762120.
GenomeReviews	Gene locus Tcr_2198 in contig CP000109_GR.
KEGG	tcx:Tcr_2198.
NMPDR	fig|317025.3.peg.2189.
PATRIC	23976546. VBIThiCru83387_2293.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0594.
HOGENOM	HBG728160.
OMA	RKNIKHA.
PhylomeDB	Q31DI7.
Enzyme and pathway databases
BioCyc	TCRU317025:TCR_2198-MONOMER.
Family and domain databases
HAMAP	MF_00227. RNase_P. [Tree]
InterPro	IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR000100. RNase_P. [Graphical view]
Gene3D	G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
KO	K03536.
Pfam	PF00825. Ribonuclease_P. 1 hit. [Graphical view]
ProDom	PD003629. Ribonuclease_P. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMs	TIGR00188. RnpA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q31DI7_THICR

Accession

Primary (citable) accession number: Q31DI7

Entry history

Integrated into UniProtKB/TrEMBL:	December 6, 2005
Last sequence update:	December 6, 2005
Last modified:	December 14, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)