Reviewed, UniProtKB/Swiss-Prot Q31D25 (PPNK1_PROM9)

Names and origin

Protein names

Recommended name:
    Probable inorganic polyphosphate/ATP-NAD kinase 1
      Short name=Poly(P)/ATP NAD kinase 1
    EC=2.7.1.23

Gene names

Name:	ppnK1
Ordered Locus Names:	PMT9312_0158

Organism

Prochlorococcus marinus (strain MIT 9312) [Complete proteome] [HAMAP]

Taxonomic identifier

74546 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	303 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity.
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the NAD kinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding NAD NADP Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 303	303	Probable inorganic polyphosphate/ATP-NAD kinase 1 HAMAP MF_00361		PRO_0000229668

Sequences

	Sequence		Length	Mass (Da)
	Q31D25-1 [UniParc]. Last modified December 6, 2005. Version 1. Checksum: 14B8B84A93AD5792	FASTA	303	34,065
	10 20 30 40 50 60 MKLSLVLIIY RSDSSIALEA SKFCEEVLKA KNIKSNRIAS DFHRDEIEKN LYNTKFQPDI 70 80 90 100 110 120 GIVLGGDGTF LKCANALADY DIPLLSINIG GNLGFLTQEK DFLFDKSFIE ILENEEYIID 130 140 150 160 170 180 SRNRLNCNVC ISERSPEKKI IKSYDALNDF YFKSVEEAIS PTNQIQIEID NEKVNEYKGD 190 200 210 220 230 240 GLIISTSTGS TAYSMAAGGP IVHPSIDAMI INPICPMSLA SRPIVIPNTS KVIIKPVKKS 250 260 270 280 290 300 KGEIKLWRDG SKCMTIKETY YCEIKKGKAP CKIIKFKKST NYYNTLIKKL DWKGDLSLKN SKN

References

[1]

"Complete sequence of Prochlorococcus marinus str. MIT 9312." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Thiel J., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000111 Genomic DNA. Translation: ABB49220.1.
RefSeq	YP_396656.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3764943.
GenomeReviews	Gene locus PMT9312_0158 in contig CP000111_GR.
KEGG	pmi:PMT9312_0158.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q31D25.
OMA	Q31D25. KLHWAGS.
Enzyme and pathway databases
BioCyc	PMAR74546:PMT9312_0158-MON.
Family and domain databases
HAMAP	MF_00361. [Tree]
InterPro	IPR017438. ATP-NAD_kinase_PpnK-typ_a/b. IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. ATP_NADK. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit. G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PPNK1_PROM9

Accession

Primary (citable) accession number: Q31D25

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	December 6, 2005
Last modified:	June 16, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)