ID   DNCH_PROM9              Reviewed;         150 AA.
AC   Q31D08;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   27-MAR-2024, entry version 83.
DE   RecName: Full=1,4-dihydroxy-2-naphthoyl-CoA hydrolase {ECO:0000255|HAMAP-Rule:MF_02101};
DE            Short=DHNA-CoA hydrolase {ECO:0000255|HAMAP-Rule:MF_02101};
DE            EC=3.1.2.28 {ECO:0000255|HAMAP-Rule:MF_02101};
DE   AltName: Full=DHNA-CoA thioesterase {ECO:0000255|HAMAP-Rule:MF_02101};
GN   OrderedLocusNames=PMT9312_0175;
OS   Prochlorococcus marinus (strain MIT 9312).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales;
OC   Prochlorococcaceae; Prochlorococcus.
OX   NCBI_TaxID=74546;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MIT 9312;
RX   PubMed=16556843; DOI=10.1126/science.1122050;
RA   Coleman M.L., Sullivan M.B., Martiny A.C., Steglich C., Barry K.,
RA   Delong E.F., Chisholm S.W.;
RT   "Genomic islands and the ecology and evolution of Prochlorococcus.";
RL   Science 311:1768-1770(2006).
CC   -!- FUNCTION: Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA
CC       (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in
CC       phylloquinone (vitamin K1) biosynthesis. {ECO:0000255|HAMAP-
CC       Rule:MF_02101}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-
CC         naphthoate + CoA + H(+); Xref=Rhea:RHEA:26309, ChEBI:CHEBI:11173,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:58897; EC=3.1.2.28; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_02101};
CC   -!- PATHWAY: Cofactor biosynthesis; phylloquinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_02101}.
CC   -!- PATHWAY: Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate
CC       biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 7/7.
CC       {ECO:0000255|HAMAP-Rule:MF_02101}.
CC   -!- SIMILARITY: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.
CC       DHNA-CoA hydrolase subfamily. {ECO:0000255|HAMAP-Rule:MF_02101}.
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DR   EMBL; CP000111; ABB49237.1; -; Genomic_DNA.
DR   RefSeq; WP_011375741.1; NC_007577.1.
DR   AlphaFoldDB; Q31D08; -.
DR   SMR; Q31D08; -.
DR   STRING; 74546.PMT9312_0175; -.
DR   KEGG; pmi:PMT9312_0175; -.
DR   eggNOG; COG0824; Bacteria.
DR   HOGENOM; CLU_101141_5_3_3; -.
DR   OrthoDB; 9800856at2; -.
DR   UniPathway; UPA00995; -.
DR   UniPathway; UPA01057; UER01033.
DR   Proteomes; UP000002715; Chromosome.
DR   GO; GO:0016790; F:thiolester hydrolase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042372; P:phylloquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   CDD; cd00586; 4HBT; 1.
DR   Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR   HAMAP; MF_02101; DHNA_CoA_hydrolase; 1.
DR   InterPro; IPR022829; DHNA_CoA_hydrolase.
DR   InterPro; IPR029069; HotDog_dom_sf.
DR   PANTHER; PTHR31793; 4-HYDROXYBENZOYL-COA THIOESTERASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR31793:SF44; ESTERASE SLL0410-RELATED; 1.
DR   Pfam; PF13279; 4HBT_2; 1.
DR   SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 1.
PE   3: Inferred from homology;
KW   Hydrolase.
FT   CHAIN           1..150
FT                   /note="1,4-dihydroxy-2-naphthoyl-CoA hydrolase"
FT                   /id="PRO_0000377021"
FT   ACT_SITE        19
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02101"
SQ   SEQUENCE   150 AA;  17453 MW;  305291276DA63DA9 CRC64;
     MKPSDWLILQ KKVRFGDCDS AGVIHFHNLL KWSHEAWEES IEIYGIPYQD IFPDFSIRKS
     QIIFPIVNCE ANYLAPIKIG DLLKVKIYPH KINPHLFRVN SFFMKNGNKV AEGKIIHCSL
     DVDSRNKIEL PDQLERWIEA SNISTNLKEC
//