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Q31D08 (DNCH_PROM9) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1,4-dihydroxy-2-naphthoyl-CoA hydrolase

Short name=DHNA-CoA hydrolase
EC=3.1.2.28
Alternative name(s):
DHNA-CoA thioesterase
Gene names
Ordered Locus Names:PMT9312_0175
OrganismProchlorococcus marinus (strain MIT 9312) [Complete proteome] [HAMAP]
Taxonomic identifier74546 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus

Protein attributes

Sequence length150 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis By similarity. HAMAP-Rule MF_02101

Catalytic activity

1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-naphthoate + CoA. HAMAP-Rule MF_02101

Pathway

Cofactor biosynthesis; phylloquinone biosynthesis. HAMAP-Rule MF_02101

Sequence similarities

Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processphylloquinone biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionacyl-CoA hydrolase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 1501501,4-dihydroxy-2-naphthoyl-CoA hydrolase HAMAP-Rule MF_02101
PRO_0000377021

Sites

Active site191 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q31D08 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: 305291276DA63DA9

FASTA15017,453
        10         20         30         40         50         60 
MKPSDWLILQ KKVRFGDCDS AGVIHFHNLL KWSHEAWEES IEIYGIPYQD IFPDFSIRKS 

        70         80         90        100        110        120 
QIIFPIVNCE ANYLAPIKIG DLLKVKIYPH KINPHLFRVN SFFMKNGNKV AEGKIIHCSL 

       130        140        150 
DVDSRNKIEL PDQLERWIEA SNISTNLKEC 

« Hide

References

[1]"Complete sequence of Prochlorococcus marinus str. MIT 9312."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Thiel J., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MIT 9312.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000111 Genomic DNA. Translation: ABB49237.1.
RefSeqYP_396673.1. NC_007577.1.

3D structure databases

ProteinModelPortalQ31D08.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING74546.PMT9312_0175.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABB49237; ABB49237; PMT9312_0175.
GeneID3764960.
KEGGpmi:PMT9312_0175.
PATRIC23003968. VBIProMar70153_0179.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0824.
HOGENOMHOG000056134.
KOK12073.
OMAIVNCEAN.
OrthoDBEOG6KWXZW.

Enzyme and pathway databases

BioCycPMAR74546:GHRG-180-MONOMER.
UniPathwayUPA00995.

Family and domain databases

Gene3D3.10.129.10. 1 hit.
HAMAPMF_02101. DHNA_CoA_hydrolase.
InterProIPR022829. DHNA_CoA_hydrolase.
IPR029069. HotDog_dom.
[Graphical view]
SUPFAMSSF54637. SSF54637. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDNCH_PROM9
AccessionPrimary (citable) accession number: Q31D08
Entry history
Integrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: December 6, 2005
Last modified: June 11, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways