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Q31D03 (Q31D03_PROM9) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutathione synthetase HAMAP-Rule MF_00162

EC=6.3.2.3 HAMAP-Rule MF_00162
Alternative name(s):
GSH synthetase HAMAP-Rule MF_00162
Glutathione synthase HAMAP-Rule MF_00162
Gene names
Name:gshB HAMAP-Rule MF_00162
Ordered Locus Names:PMT9312_0180 EMBL ABB49242.1
OrganismProchlorococcus marinus (strain MIT 9312) [Complete proteome] [HAMAP] EMBL ABB49242.1
Taxonomic identifier74546 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus

Protein attributes

Sequence length307 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione. HAMAP-Rule MF_00162

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. HAMAP-Rule MF_00162

Pathway

Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2. HAMAP-Rule MF_00162

Sequence similarities

Belongs to the prokaryotic GSH synthase family. HAMAP-Rule MF_00162

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00162

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain120 – 304185ATP-grasp By similarity HAMAP-Rule MF_00162
Nucleotide binding146 – 20257ATP By similarity HAMAP-Rule MF_00162

Sites

Metal binding2751Magnesium or manganese By similarity HAMAP-Rule MF_00162
Metal binding2771Magnesium or manganese By similarity HAMAP-Rule MF_00162

Sequences

Sequence LengthMass (Da)Tools
Q31D03 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: 0E2D0144CD47D6E1

FASTA30734,091
        10         20         30         40         50         60 
MKFLFVIDPI KNINPLKDST AALMQASSKK NIEIWSCTPQ DLEARGDEVW ASSVKVEVNP 

        70         80         90        100        110        120 
WISFKENDCI PLAEFNCIWM RKDPPVNEAY LYATHLLEVA ERKGVKVINK PSSLRAWNEK 

       130        140        150        160        170        180 
LGALRYSHLM APTIVASKVK DLINFANINN EVVIKPLGGK GGQGVIRINK NSPGIKSIIE 

       190        200        210        220        230        240 
LITSQEELPV MMQKFIPKVI EGDKRIIIVN GEAIGSINRI PQGGDFRSNL ALGGKAEPTL 

       250        260        270        280        290        300 
LTEKEKSICS ELSQHFKDEG LFFVGIDVIN GMLSEINVTS PTGLREIENL SNKNVSEEVI 


EKLIEII 

« Hide

References

[1]"Complete sequence of Prochlorococcus marinus str. MIT 9312."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Thiel J., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MIT 9312.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000111 Genomic DNA. Translation: ABB49242.1.
RefSeqYP_396678.1. NC_007577.1.

3D structure databases

ProteinModelPortalQ31D03.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING74546.PMT9312_0180.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABB49242; ABB49242; PMT9312_0180.
GeneID3764965.
KEGGpmi:PMT9312_0180.
PATRIC23003978. VBIProMar70153_0184.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0189.
HOGENOMHOG000265022.
KOK01920.
OMADWKIARA.
OrthoDBEOG6WMHWB.

Enzyme and pathway databases

BioCycPMAR74546:GHRG-185-MONOMER.
UniPathwayUPA00142; UER00210.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
HAMAPMF_00162. GSH_S.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR006284. Glut_synth_pro.
IPR004218. GSHS_ATP-bd.
IPR004215. GSHS_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PfamPF02955. GSH-S_ATP. 1 hit.
PF02951. GSH-S_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01380. glut_syn. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ31D03_PROM9
AccessionPrimary (citable) accession number: Q31D03
Entry history
Integrated into UniProtKB/TrEMBL: December 6, 2005
Last sequence update: December 6, 2005
Last modified: June 11, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)