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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Prochlorococcus marinus (strain MIT 9312)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:PMT9312_0189
OrganismiProchlorococcus marinus (strain MIT 9312)
Taxonomic identifieri74546 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000002715 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002420651 – 604Arginine--tRNA ligaseAdd BLAST604

Proteomic databases

PRIDEiQ31CZ4.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi74546.PMT9312_0189.

Structurei

3D structure databases

ProteinModelPortaliQ31CZ4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi142 – 152"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
HOGENOMiHOG000247212.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG091H01RF.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q31CZ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLIIFKELTK QFEQSLLDSL EKNDKRGEFD NLRKNLVTQS SKEEFGDYQC
60 70 80 90 100
NVCLCLSKIY KKKPREISED FVYLLNKNKS ISKLCKSLEI AGPGFINIKL
110 120 130 140 150
KDEVLINEIK SNIQCPRAGI PLIKKDLDSG LSNKVIVDFS SPNIAKEMHV
160 170 180 190 200
GHLRSTIIGD SISRIFELRG YQVLRLNHVG DWGTQFGMLI TQLKDLYSND
210 220 230 240 250
LEEIGKIKIS DLVEFYKASK KRFDNESEFQ KRSREEVVKL QSGDSKSIQA
260 270 280 290 300
WKLLCDQSRK EFDEIYKNLK IKIKERGESF YNPFLKSVIE DLKFKKILIE
310 320 330 340 350
DQGAKCVFLD GMTNKEGKPL PLIVQKKDGG FNYATTDLAA IRYRFNKAPN
360 370 380 390 400
GDDASRIIYV TDHGQANHFA GVFQVAKKAK WIPDKCQVDH VPFGLVQGID
410 420 430 440 450
GKKLKTREGE TIRLKDLLNE AVRRAKEDLL KRLEDEDRYE TEEFIANTSR
460 470 480 490 500
IIGLGAVKYA DLSQNRITNY QFSFDKMLSL NGNTAPYLLY TLVRISGIKR
510 520 530 540 550
KNDFVYDSED FQYINYEHKS EWKLIRKLLK FDEVIISIEK DLMPNRLCNY
560 570 580 590 600
LFELCQTFNR FYDQVPILKE EKNIKISRLN LCDLTAKTLK LSLELLGIET

LERM
Length:604
Mass (Da):69,957
Last modified:December 6, 2005 - v1
Checksum:i0709D1B49785AF06
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000111 Genomic DNA. Translation: ABB49251.1.
RefSeqiWP_011375755.1. NC_007577.1.

Genome annotation databases

EnsemblBacteriaiABB49251; ABB49251; PMT9312_0189.
KEGGipmi:PMT9312_0189.

Similar proteinsi

Entry informationi

Entry nameiSYR_PROM9
AccessioniPrimary (citable) accession number: Q31CZ4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: December 6, 2005
Last modified: November 22, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families