Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q31CZ4 (SYR_PROM9) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:PMT9312_0189
OrganismProchlorococcus marinus (strain MIT 9312) [Complete proteome] [HAMAP]
Taxonomic identifier74546 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus

Protein attributes

Sequence length604 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 604604Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242065

Regions

Motif142 – 15211"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q31CZ4 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: 0709D1B49785AF06

FASTA60469,957
        10         20         30         40         50         60 
MLIIFKELTK QFEQSLLDSL EKNDKRGEFD NLRKNLVTQS SKEEFGDYQC NVCLCLSKIY 

        70         80         90        100        110        120 
KKKPREISED FVYLLNKNKS ISKLCKSLEI AGPGFINIKL KDEVLINEIK SNIQCPRAGI 

       130        140        150        160        170        180 
PLIKKDLDSG LSNKVIVDFS SPNIAKEMHV GHLRSTIIGD SISRIFELRG YQVLRLNHVG 

       190        200        210        220        230        240 
DWGTQFGMLI TQLKDLYSND LEEIGKIKIS DLVEFYKASK KRFDNESEFQ KRSREEVVKL 

       250        260        270        280        290        300 
QSGDSKSIQA WKLLCDQSRK EFDEIYKNLK IKIKERGESF YNPFLKSVIE DLKFKKILIE 

       310        320        330        340        350        360 
DQGAKCVFLD GMTNKEGKPL PLIVQKKDGG FNYATTDLAA IRYRFNKAPN GDDASRIIYV 

       370        380        390        400        410        420 
TDHGQANHFA GVFQVAKKAK WIPDKCQVDH VPFGLVQGID GKKLKTREGE TIRLKDLLNE 

       430        440        450        460        470        480 
AVRRAKEDLL KRLEDEDRYE TEEFIANTSR IIGLGAVKYA DLSQNRITNY QFSFDKMLSL 

       490        500        510        520        530        540 
NGNTAPYLLY TLVRISGIKR KNDFVYDSED FQYINYEHKS EWKLIRKLLK FDEVIISIEK 

       550        560        570        580        590        600 
DLMPNRLCNY LFELCQTFNR FYDQVPILKE EKNIKISRLN LCDLTAKTLK LSLELLGIET 


LERM 

« Hide

References

[1]"Complete sequence of Prochlorococcus marinus str. MIT 9312."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Thiel J., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MIT 9312.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000111 Genomic DNA. Translation: ABB49251.1.
RefSeqYP_396687.1. NC_007577.1.

3D structure databases

ProteinModelPortalQ31CZ4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING74546.PMT9312_0189.

Proteomic databases

PRIDEQ31CZ4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABB49251; ABB49251; PMT9312_0189.
GeneID3764974.
KEGGpmi:PMT9312_0189.
PATRIC23003996. VBIProMar70153_0193.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMAYVKFHDE.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycPMAR74546:GHRG-194-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_PROM9
AccessionPrimary (citable) accession number: Q31CZ4
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: December 6, 2005
Last modified: May 14, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries