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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Prochlorococcus marinus (strain MIT 9312)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:PMT9312_0415
OrganismiProchlorococcus marinus (strain MIT 9312)
Taxonomic identifieri74546 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000002715 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003255081 – 498Probable malate:quinone oxidoreductaseAdd BLAST498

Proteomic databases

PRIDEiQ31CB9.

Interactioni

Protein-protein interaction databases

STRINGi74546.PMT9312_0415.

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
KOiK00116.
OMAiEPIAATK.
OrthoDBiPOG091H0B7C.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00212. MQO. 1 hit.
InterProiView protein in InterPro
IPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
PANTHERiPTHR13847:SF224. PTHR13847:SF224. 1 hit.
PfamiView protein in Pfam
PF06039. Mqo. 1 hit.
SUPFAMiSSF51905. SSF51905. 1 hit.

Sequencei

Sequence statusi: Complete.

Q31CB9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSSKNPTND NSYFDAVLVG AGIMSSTLAL LISEVLPDIK FLIIEKLKAP
60 70 80 90 100
GSESTGAFNN AGTGHAANCE LNYTPLDEKG NLKIDKALSI NRSFERSMSL
110 120 130 140 150
WASLYESGKI DIKKFLKFIP HISFVSGQDN ISFLKKRFQK MTDNPEFIDM
160 170 180 190 200
EFSTSFDEIS SWAPLITKDR NPSTQIAATR IGRGTDINFE ALTKEYLSLV
210 220 230 240 250
SLNKNVEIRY KTELVDLKKI DKKQWELEIS SEGRKTSIRT GYVFLGAGGK
260 270 280 290 300
TINYLQKSKI PEAKSYGGFP VSGKWLICEK KDLTEKHNSK VYGKADIGSP
310 320 330 340 350
PMSVPHLDTR WIDNKKLLLY GPFAGFTTKF LKQSSYFDLF SSIKKNNIFS
360 370 380 390 400
MLDVGFKNND LINYLISQSL KNHNSRVDNL KNMMPSANPS DWYLKNAGQR
410 420 430 440 450
VQIIKKTEGG GSLKFGTEIV NSSDGSLSAL LGASPGASTA VSIMVEVLEK
460 470 480 490
SVLLLNDKHN LQKKINDLIY PELSDSENKS IYIKDIKKRN NSIFGFHP
Length:498
Mass (Da):55,579
Last modified:December 6, 2005 - v1
Checksum:i8A2776297EB5CA11
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000111 Genomic DNA. Translation: ABB49476.1.
RefSeqiWP_011375975.1. NC_007577.1.

Genome annotation databases

EnsemblBacteriaiABB49476; ABB49476; PMT9312_0415.
KEGGipmi:PMT9312_0415.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiMQO_PROM9
AccessioniPrimary (citable) accession number: Q31CB9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: December 6, 2005
Last modified: June 7, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families