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Q31BS1 (AROA_PROM9) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:PMT9312_0613
OrganismProchlorococcus marinus (strain MIT 9312) [Complete proteome] [HAMAP]
Taxonomic identifier74546 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length436 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4364363-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_1000012460

Sequences

Sequence LengthMass (Da)Tools
Q31BS1 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: 913F1A99EDF0F7F8

FASTA43646,535
        10         20         30         40         50         60 
MNNVRKIKGG SNLKGKIKVP GDKSISHRAL IIGSIAQGET TIEGFLHSED PLSTADCLRK 

        70         80         90        100        110        120 
LGVNIPDIKE DEPFTISGLG LDGIKEPKEI LNCGNSGTTM RLLMGLLAGQ EGKNFILTGD 

       130        140        150        160        170        180 
TSLNERPMGR VNKPLSLMGG IISGRESGNK APISIYGNKL KGCVIGTPIA SAQVKSAILL 

       190        200        210        220        230        240 
AGLKASGTTS VIEPASSRDH TERMLKAFGA NISIRGELGR NVVIKSGGNL IGQRILIPGD 

       250        260        270        280        290        300 
ISSASFWMIA ASIVPNSEVL IKNVGLNPTR TGILNVMDSM GCNYEILDKS TIAGEPIGSI 

       310        320        330        340        350        360 
KVKTANNLRS FTIEGDILPK LIDEIPILTV AACFCNGVSE IKDAQELRFK ETDRLKVMAR 

       370        380        390        400        410        420 
QLSKFGAEIT EKEDGLIING QSKFHSAEVD SETDHRVSMS LAIASLVAKG TSKIMRADAS 

       430 
YVSYPSFWED LAKLTN

« Hide

References

[1]"Complete sequence of Prochlorococcus marinus str. MIT 9312."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Thiel J., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MIT 9312.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000111 Genomic DNA. Translation: ABB49674.1.
RefSeqYP_397110.1. NC_007577.1.

3D structure databases

HSSPHSSP built from PDB template 2BJB based on UniProtKB P22487.
ProteinModelPortalQ31BS1.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ31BS1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3765413.
GenomeReviewsGene locus PMT9312_0613 in contig CP000111_GR.
KEGGpmi:PMT9312_0613.
PATRIC23004906. VBIProMar70153_0633.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0128.
HOGENOMHBG646626.
OMALECANIS.
PhylomeDBQ31BS1.
ProtClustDBPRK02427.

Enzyme and pathway databases

BioCycPMAR74546:PMT9312_0613-MONOMER.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_PROM9
AccessionPrimary (citable) accession number: Q31BS1
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 6, 2005
Last modified: January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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