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Q31BK2 (AROB_PROM9) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:PMT9312_0682
OrganismProchlorococcus marinus (strain MIT 9312) [Complete proteome] [HAMAP]
Taxonomic identifier74546 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length363 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm Probable HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3633633-dehydroquinate synthase HAMAP MF_00110
PRO_0000231110

Sequences

Sequence LengthMass (Da)Tools
Q31BK2 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: D6ABE17D0C8E56E1

FASTA36340,806
        10         20         30         40         50         60 
MNKRKILVPL GNKSYEVTIE AGILNNISEE LLKIGITKNR KILVISNEEI SNFYGEKFLN 

        70         80         90        100        110        120 
DLKDNKFQVQ MFLIKAGESY KNLKTLSEIY DVAFEFGLDR NSIIIALGGG IVGDVSGFAA 

       130        140        150        160        170        180 
ATWLRGIEYI QIPTTLLSMV DSSVGGKTGV NHPKGKNLIG AFNQPKAVFI DPETLKSLPK 

       190        200        210        220        230        240 
REFSAGMAEV IKYGVIRDKE LFEYLEIEKN KNELINLKNE YLIKIINSSI KTKSYIVSQD 

       250        260        270        280        290        300 
EHENGVRAIL NYGHSFGHVI ENLCGYGKFL HGEAISIGMN IAGEIAIDKG LWSKEELERQ 

       310        320        330        340        350        360 
KNLLKSYDLP TEIPKINKED VLTILMGDKK VRNGKMRFIL PKEIGVVDIY DDVEDALFLK 


FFS

« Hide

References

[1]"Complete sequence of Prochlorococcus marinus str. MIT 9312."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Thiel J., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MIT 9312.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000111 Genomic DNA. Translation: ABB49743.1.
RefSeqYP_397179.1. NC_007577.1.

3D structure databases

ProteinModelPortalQ31BK2.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ31BK2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3765483.
GenomeReviewsGene locus PMT9312_0682 in contig CP000111_GR.
KEGGpmi:PMT9312_0682.
PATRIC23005060. VBIProMar70153_0709.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0337.
HOGENOMHBG632303.
OMAGTFTQPD.
PhylomeDBQ31BK2.
ProtClustDBPRK00002.

Enzyme and pathway databases

BioCycPMAR74546:PMT9312_0682-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_PROM9
AccessionPrimary (citable) accession number: Q31BK2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: December 6, 2005
Last modified: January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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