Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q31AX4

- SYL_PROM9

UniProt

Q31AX4 - SYL_PROM9

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Leucine--tRNA ligase

Gene

leuS

Organism
Prochlorococcus marinus (strain MIT 9312)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei625 – 6251ATPUniRule annotation

GO - Molecular functioni

  1. aminoacyl-tRNA editing activity Source: InterPro
  2. ATP binding Source: UniProtKB-HAMAP
  3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPMAR74546:GHRG-933-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine--tRNA ligaseUniRule annotation (EC:6.1.1.4UniRule annotation)
Alternative name(s):
Leucyl-tRNA synthetaseUniRule annotation
Short name:
LeuRSUniRule annotation
Gene namesi
Name:leuSUniRule annotation
Ordered Locus Names:PMT9312_0911
OrganismiProchlorococcus marinus (strain MIT 9312)
Taxonomic identifieri74546 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000002715: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 856856Leucine--tRNA ligasePRO_1000009394Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi74546.PMT9312_0911.

Structurei

3D structure databases

ProteinModelPortaliQ31AX4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi53 – 6311"HIGH" regionAdd
BLAST
Motifi622 – 6265"KMSKS" region

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0495.
HOGENOMiHOG000200747.
KOiK01869.
OMAiHISHELW.
OrthoDBiEOG63Z74X.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPiMF_00049_B. Leu_tRNA_synth_B.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
PfamiPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 3 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view]
PRINTSiPR00985. TRNASYNTHLEU.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsiTIGR00396. leuS_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q31AX4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MISPDKQYET DTNLYNPSEI EKKWQSIWTE NNLYKTDELT ENSDKFYALS
60 70 80 90 100
MFPYPSGNLH MGHVRNYVIT DLIARFQRFK GKSVLHPMGW DAFGLPAENA
110 120 130 140 150
AIERGISPSV WTKKNISHMK SQLKLLGLSV DWDREFATCD ENYYIWTQYL
160 170 180 190 200
FLELYKAGLV YQKESEVNWD PIDNTVLANE QVDSEGKSWR SGALVEKKLL
210 220 230 240 250
KQWFLRITNY ADELLKDLEK LDNWPERVKI MQDNWIGKSI GTNINFNINT
260 270 280 290 300
NPEKKITVFT TRPDTLFGVT YLAISINHSL IKNISDQETI QDIENLKQYL
310 320 330 340 350
KNNKNNELEK IGIKTSLIAI NPVNSEPIPI WVASYVLDEY GTGAVMGVPA
360 370 380 390 400
HDLRDFEFAK KNNIDIKHVI IKDKSEKTKE LDEAYVENGY LINSNHFNGI
410 420 430 440 450
ANTIAKLKIS EEGVNNGWAE NKIQYRLRDW LISRQRYWGC PIPIVNCKKC
460 470 480 490 500
GSVPLNQSEL PVALPKDIDI SANKINALGD NYNWINTTCP KCGIAAKKET
510 520 530 540 550
DTMDTFMCSS WYFLRYPSSR CSTKPFEKIE INNWLPVDQY VGGVEHAILH
560 570 580 590 600
LLYARFFTKA LRDNELFEID EPFKKLLTQG MVQSAAYKNN KTGKYISPSD
610 620 630 640 650
INDLSNPTDP IDNSKLEVLF EKMSKSKYNG IDPESVIKKY GADTARMFIL
660 670 680 690 700
FKAPPEKDLE WGDSDVEGQF RFLSRIWKLY ISCSKDINSK SKSYPNKEKT
710 720 730 740 750
LIKSMNIAIK EITNDISNNQ FNTAISELMK FYNSLSNNIN DVNNNLKIDA
760 770 780 790 800
LKTFCILLAP FAPHISEEIW LLIGFKNSVH LEHWPSFNAE ALKEDSYVLV
810 820 830 840 850
IQVNGKVRDK ININNEMNED QIKELTLKRP NILKWTQDKE IRKIIIVKGK

IMNIVV
Length:856
Mass (Da):98,666
Last modified:December 6, 2005 - v1
Checksum:i0ADE75F2D85B2663
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000111 Genomic DNA. Translation: ABB49971.1.
RefSeqiYP_397407.1. NC_007577.1.

Genome annotation databases

EnsemblBacteriaiABB49971; ABB49971; PMT9312_0911.
GeneIDi3765713.
KEGGipmi:PMT9312_0911.
PATRICi23005582. VBIProMar70153_0968.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000111 Genomic DNA. Translation: ABB49971.1 .
RefSeqi YP_397407.1. NC_007577.1.

3D structure databases

ProteinModelPortali Q31AX4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 74546.PMT9312_0911.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABB49971 ; ABB49971 ; PMT9312_0911 .
GeneIDi 3765713.
KEGGi pmi:PMT9312_0911.
PATRICi 23005582. VBIProMar70153_0968.

Phylogenomic databases

eggNOGi COG0495.
HOGENOMi HOG000200747.
KOi K01869.
OMAi HISHELW.
OrthoDBi EOG63Z74X.

Enzyme and pathway databases

BioCyci PMAR74546:GHRG-933-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPi MF_00049_B. Leu_tRNA_synth_B.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view ]
PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
Pfami PF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 3 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view ]
PRINTSi PR00985. TRNASYNTHLEU.
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Prochlorococcus marinus str. MIT 9312."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Thiel J., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MIT 9312.

Entry informationi

Entry nameiSYL_PROM9
AccessioniPrimary (citable) accession number: Q31AX4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 6, 2005
Last modified: October 29, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3