Q319F4 (Q319F4_PROM9) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA 2 HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase 2 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 2 HAMAP MF_01401

Gene names

Name:	msrA2 HAMAP MF_01401
Ordered Locus Names:	PMT9312_1431

Organism

Prochlorococcus marinus (strain MIT 9312) [Complete proteome] [HAMAP]

Taxonomic identifier

74546 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	200 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Domain	Signal EMBL ABB50491.1
Molecular function	Oxidoreductase HAMAP MF_01401 SAAS SAAS002569 EMBL ABB50491.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 23	23	Potential EMBL ABB50491.1
	Chain	24 – 200	177	Potential EMBL ABB50491.1		PRO_5000102628
Sites
	Active site	31	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	Q319F4 [UniParc]. Last modified December 6, 2005. Version 1. Checksum: B1F2F027EEADACE1	FASTA	200	23,037
	10 20 30 40 50 60 MKYFLPLIIA LSIFINPVNA FAEELILAGG CFWCLEHDLE SLKGINFVQS GYSGGDLQNP 70 80 90 100 110 120 TYENHEGHQE VVLVNYDSQL VTLPEILRLY LRNIDPLDGK GQFCDRGDSY RPVIFFKDAT 130 140 150 160 170 180 EESDATNAIV SASNELRVPL EKIAVELKSK GQFWLAEEYH QDFAERNELK YKFYRFSCGR 190 200 DQRLDKLWGN NARSTNLWIE

References

[1]

"Complete sequence of Prochlorococcus marinus str. MIT 9312." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Thiel J., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MIT 9312.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000111 Genomic DNA. Translation: ABB50491.1.
RefSeq	YP_397927.1. NC_007577.1.
3D structure databases
ProteinModelPortal	Q319F4.
ModBase	Search...
Protein-protein interaction databases
STRING	Q319F4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3766247.
GenomeReviews	Gene locus PMT9312_1431 in contig CP000111_GR.
KEGG	pmi:PMT9312_1431.
PATRIC	23006806. VBIProMar70153_1567.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0225.
HOGENOM	HBG748152.
OMA	KIEYDVA.
PhylomeDB	Q319F4.
ProtClustDB	CLSK922153.
Enzyme and pathway databases
BioCyc	PMAR74546:PMT9312_1431-MONOMER.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q319F4_PROM9

Accession

Primary (citable) accession number: Q319F4

Entry history

Integrated into UniProtKB/TrEMBL:	December 6, 2005
Last sequence update:	December 6, 2005
Last modified:	December 14, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)