Q319F3 (Q319F3_PROM9) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL ABB50492.1
EC=2.4.1.182 EMBL ABB50492.1

Gene names

Ordered Locus Names:

PMT9312_1432

Organism

Prochlorococcus marinus (strain MIT 9312) [Complete proteome] [HAMAP]

Taxonomic identifier

74546 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	392 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 EMBL ABB50492.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q319F3 [UniParc]. Last modified December 6, 2005. Version 1. Checksum: 11ED254310CE8467	FASTA	392	44,927
	10 20 30 40 50 60 MNKKIFISTG EVSGDLHGGL LSKALFDEAE KKSLDLEICG LGGERMKKEG VKILQDTTSI 70 80 90 100 110 120 SAIGIWEALP LIIPTIRIQK RFYKLLKKYP PDCLILIDYM GPNIKIGRKL KRSKTKIPIF 130 140 150 160 170 180 YYIAPQEWAW RVGNNTTTDL INFSDKIFAI FRQEAAFYKK RGGNVLWVGH PMIDLTKKLP 190 200 210 220 230 240 LKKNARTILN LRPNQNILLL MPASRPQELK YILPTFMRTA RKLQKKYPSL VVYIPSCRKV 250 260 270 280 290 300 FDERFKKAFR KYQVIGQVIS QKDNAKLKPY IYSLTKIAIC KSGTVNMELA LYGIPQIVGY 310 320 330 340 350 360 RVSRVTAFIA KKILNFKVKF ISPVNLLVNK LIIPEFVQGD FDEKKIFYKA CRILDLTSEK 370 380 390 SKIKKGYTLL KKELGEEGVV QRAAKEIINS II

References

[1]

"Complete sequence of Prochlorococcus marinus str. MIT 9312." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Thiel J., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MIT 9312.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000111 Genomic DNA. Translation: ABB50492.1.
RefSeq	YP_397928.1. NC_007577.1.
3D structure databases
ProteinModelPortal	Q319F3.
ModBase	Search...
Protein-protein interaction databases
STRING	Q319F3.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3766248.
GenomeReviews	Gene locus PMT9312_1432 in contig CP000111_GR.
KEGG	pmi:PMT9312_1432.
PATRIC	23006808. VBIProMar70153_1568.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0763.
HOGENOM	HBG584837.
OMA	PDFNLGL.
PhylomeDB	Q319F3.
ProtClustDB	PRK00025.
Enzyme and pathway databases
BioCyc	PMAR74546:PMT9312_1432-MONOMER.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q319F3_PROM9

Accession

Primary (citable) accession number: Q319F3

Entry history

Integrated into UniProtKB/TrEMBL:	December 6, 2005
Last sequence update:	December 6, 2005
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)