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Protein

tRNA pseudouridine synthase A

Gene

truA

Organism
Prochlorococcus marinus (strain MIT 9312)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei52NucleophileUniRule annotation1
Binding sitei110SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciPMAR74546:G1G51-1692-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)
Alternative name(s):
tRNA pseudouridine(38-40) synthaseUniRule annotation
tRNA pseudouridylate synthase IUniRule annotation
tRNA-uridine isomerase IUniRule annotation
Gene namesi
Name:truAUniRule annotation
Ordered Locus Names:PMT9312_1626
OrganismiProchlorococcus marinus (strain MIT 9312)
Taxonomic identifieri74546 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000002715 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000171391 – 268tRNA pseudouridine synthase AAdd BLAST268

Proteomic databases

PRIDEiQ318K9

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi74546.PMT9312_1626

Structurei

3D structure databases

ProteinModelPortaliQ318K9
SMRiQ318K9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DI7 Bacteria
COG0101 LUCA
HOGENOMiHOG000248672
KOiK06173
OMAiFLYGMVR
OrthoDBiPOG091H010Q

Family and domain databases

Gene3Di3.30.70.660, 1 hit
HAMAPiMF_00171 TruA, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001406 PsdUridine_synth_TruA
IPR020097 PsdUridine_synth_TruA_a/b_dom
IPR020095 PsdUridine_synth_TruA_C
PANTHERiPTHR11142 PTHR11142, 1 hit
PfamiView protein in Pfam
PF01416 PseudoU_synth_1, 2 hits
PIRSFiPIRSF001430 tRNA_psdUrid_synth, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00071 hisT_truA, 1 hit

Sequencei

Sequence statusi: Complete.

Q318K9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRIALLVQY DGSNYSGWQR QKNATTVQET LERALFKITH QVVKTFAAGR
60 70 80 90 100
TDAGVHASGQ VVHFNIDCVI PANSYSDILN GLLPSAIRIL ESVEVKDSWH
110 120 130 140 150
SCYSAMYRHY RYVINNSKFP NLFINNWSWH RYQKILDEVL MSNASKLMEG
160 170 180 190 200
EHDFFAFQKS GSQRKNSITK IKNVEIKRVE DLILVDIKAT GFLYGMVRLI
210 220 230 240 250
VGQLVLVGEK KISPEIFTDI WVNQKKNDVK ESAPAKGLCF VNAVYEENVF
260
KKINNNDFFP VFLIKGFS
Length:268
Mass (Da):30,695
Last modified:December 6, 2005 - v1
Checksum:iB4289F07EAB01A5F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000111 Genomic DNA Translation: ABB50686.1
RefSeqiWP_011377168.1, NC_007577.1

Genome annotation databases

EnsemblBacteriaiABB50686; ABB50686; PMT9312_1626
KEGGipmi:PMT9312_1626

Similar proteinsi

Entry informationi

Entry nameiTRUA_PROM9
AccessioniPrimary (citable) accession number: Q318K9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 6, 2005
Last modified: May 23, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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