Reviewed, UniProtKB/Swiss-Prot Q318G0 (HEM6_PROM9)

Names and origin

Protein names

Recommended name:
    Coproporphyrinogen III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase
    EC=1.3.3.3

Gene names

Name:	hemF
Ordered Locus Names:	PMT9312_1674

Organism

Prochlorococcus marinus (strain MIT 9312) [Complete proteome] [HAMAP]

Taxonomic identifier

74546 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	342 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Coproporphyrinogen-III + O(2) + 2 H(+) = protoporphyrinogen-IX + 2 CO(2) + 2 H(2)O.
Pathway	Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen III (O2 route): step 1/1.
Subcellular location	CytoplasmBy similarity.
Sequence similarities	Belongs to the aerobic coproporphyrinogen III oxidase family.

Ontologies

Keywords
Biological process	Porphyrin biosynthesis
Cellular component	Cytoplasm
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW porphyrin biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	coproporphyrinogen oxidase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 342	342	Coproporphyrinogen III oxidase, aerobic		PRO_1000019479

Sequences

	Sequence		Length	Mass (Da)
	Q318G0-1 [UniParc]. Last modified December 6, 2005. Version 1. Checksum: 317D7A7BF8D60B71	FASTA	342	39,538
	10 20 30 40 50 60 MLKEPPKNSR EKTKNLLLTL QDKICSGLEN IDGKGKFTEE SWLRDEGGGG RSRVLKNGSI 70 80 90 100 110 120 FEQAGVNFSE VQGKELPQSI ISQRPEAKGH EWFATGTSMV LHPKNPFIPT VHLNYRYFEA 130 140 150 160 170 180 GPVWWFGGGA DLTPFYPYLS DVRNFHKEHK KACEKVDKDL HKVFKPWCDE YFFLKHRNES 190 200 210 220 230 240 RGIGGIFYDY QDGSGNIYRG NNQNGEASKV SENIGKSNLN WDNLFSLAEN CGQAFLPSYL 250 260 270 280 290 300 PIIEKRANKT YTSKEREFQL YRRGRYVEFN LVWDRGTIFG LQTNGRTESI LMSLPPLARW 310 320 330 340 EYGYKAKKGS REEFLTSIFT KPQDWLNDKD LENFCMENNI FD

References

[1]

"Complete sequence of Prochlorococcus marinus str. MIT 9312." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Thiel J., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000111 Genomic DNA. Translation: ABB50735.1.
RefSeq	YP_398171.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3766496.
GenomeReviews	Gene locus PMT9312_1674 in contig CP000111_GR.
KEGG	pmi:PMT9312_1674.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q318G0.
Enzyme and pathway databases
BioCyc	PMAR74546:PMT9312_1674-MON.
Family and domain databases
HAMAP	MF_00333. [Tree]
InterPro	IPR001260. Coprogen_oxidas. [Graphical view]
Gene3D	G3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHER	PTHR10755. Coprogen_oxidas. 1 hit.
Pfam	PF01218. Coprogen_oxidas. 1 hit. [Graphical view]
PIRSF	PIRSF000166. Coproporphyri_ox. 1 hit.
PRINTS	PR00073. COPRGNOXDASE.
PROSITE	PS01021. COPROGEN_OXIDASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HEM6_PROM9

Accession

Primary (citable) accession number: Q318G0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	December 6, 2005
Last modified:	November 4, 2008
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)