Q317S2 (Q317S2_DESDG) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA gyrase subunit B HAMAP MF_01898
EC=5.99.1.3 HAMAP MF_01898

Gene names

Name:	gyrB HAMAP MF_01898
Ordered Locus Names:	Dde_0003

Organism

Desulfovibrio desulfuricans (strain G20) [Complete proteome] [HAMAP]

Taxonomic identifier

207559 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio

Protein attributes

Sequence length	797 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings By similarity. HAMAP MF_01898
Catalytic activity	ATP-dependent breakage, passage and rejoining of double-stranded DNA. HAMAP MF_01898 SAAS SAAS002288
Subunit structure	Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis. The enzyme forms an A2B2 tetramer By similarity. HAMAP MF_01898
Subcellular location	Cytoplasm By similarity HAMAP MF_01898.
Sequence similarities	Belongs to the type II topoisomerase family. HAMAP MF_01898

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_01898
Ligand	ATP-binding HAMAP MF_01898 SAAS SAAS002288 Nucleotide-binding
Molecular function	Isomerase Topoisomerase HAMAP MF_01898 SAAS SAAS002288
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA topological change Inferred from electronic annotation. Source: InterPro DNA-dependent DNA replication Inferred from electronic annotation. Source: HAMAP
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA topoisomerase (ATP-hydrolyzing) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q317S2 [UniParc]. Last modified December 6, 2005. Version 1. Checksum: F7BFEB1BDE252B43	FASTA	797	89,660
	10 20 30 40 50 60 MTNETQKQSY DAANITVLEG LSAVRMRPAM YIGSTDSRGL HHLVYEVVDN SIDEAMAGYC 70 80 90 100 110 120 DKVTVKLHLD NSVTVIDNGR GIPVDIHPKE GRPAVEVVMT VLHAGGKFDN DSYKVSGGLH 130 140 150 160 170 180 GVGVSCVNAL SEYLEVTVRR DGYKYHHRFE RGVPVKELER VGETDLRGTT IRFRPDEEIF 190 200 210 220 230 240 ETNQFSFDIL KKRFEELAYL NPGLEVEFID ERTGDTASFH YEGGIREFVK NLNSGEGGVH 250 260 270 280 290 300 SIIFASGESD NVMVDFALQY NAGYKENMLT FANNIRTKEG GTHLAGFKTA LTRAINNYIQ 310 320 330 340 350 360 NSDLPKKLKV KLSGDDVREG LTGVVSVKLP NPQFEGQTKT KLGNSEVAGI VSGLVYENLN 370 380 390 400 410 420 TYFGENPKDA KLIIEKAVDA ARARDAARKA KDLVRRKGAL SDNALPGKLA DCQSKDPSES 430 440 450 460 470 480 ELFIVEGDSA GGSAKQGRNP STQAILPLRG KILNVEKTRF DKMLANKEVK ALITAMGAGI 490 500 510 520 530 540 GEEDIDYGKL RYHKIVIMTD ADVDGAHIRT LLLTFFYRQY PELIDRGHLY IAQPPLFRVY 550 560 570 580 590 600 NSKFERFIKD ETELNTYLLE RIAKDVVIEA HNGMEFRETQ ILDLLKAIRF INARIADVEN 610 620 630 640 650 660 VGIGRNLFLA FLEYGEKLSP QFFEAPEFNG FGTYLQEKGY SVQTSVDESG LERRVYLEFE 670 680 690 700 710 720 DSNGHKTRIG NEFFNSKMYK QPYDSMADMR RICGGFSFVV DRKGERTEVE NIFVLLDHVL 730 740 750 760 770 780 QEARKGINIQ RYKGLGEMDA EQLWVTTMNP ENRVLLQVQV DDAEEANEIF EQLMGDRVEP 790 RREFIVRNAL SVQELDI

References

[1]

"Complete sequence of Desulfovibrio desulfuricans G20." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Goodwin L.A., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P. Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: G20.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000112 Genomic DNA. Translation: ABB36804.1.
RefSeq	YP_386499.1. NC_007519.1.
3D structure databases
ProteinModelPortal	Q317S2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q317S2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3755945.
GenomeReviews	Gene locus Dde_0003 in contig CP000112_GR.
KEGG	dde:Dde_0003.
NMPDR	fig|207559.3.peg.509.
PATRIC	21738913. VBIDesDes50040_0003.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0187.
HOGENOM	HBG304889.
OMA	DCSSRDP.
ProtClustDB	CLSK704341.
Family and domain databases
HAMAP	MF_01898. GyrB. [Tree]
InterPro	IPR003594. ATPase-like_ATP-bd. IPR011557. GyrB. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR001241. Topo_IIA. IPR013759. Topo_IIA_B/N_ab. IPR002288. Topo_IIA_B_C. IPR013506. Topo_IIA_bsu_dom2. IPR013760. Topo_IIA_cen. IPR018522. TopoIIA_CS. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit. G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 2 hits.
KO	K02470.
Pfam	PF00204. DNA_gyraseB. 1 hit. PF00986. DNA_gyraseB_C. 1 hit. PF02518. HATPase_c. 1 hit. [Graphical view]
PRINTS	PR00418. TPI2FAMILY.
SMART	SM00387. HATPase_c. 1 hit. SM00433. TOP2c. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMs	TIGR01059. GyrB. 1 hit.
PROSITE	PS00177. TOPOISOMERASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q317S2_DESDG

Accession

Primary (citable) accession number: Q317S2

Entry history

Integrated into UniProtKB/TrEMBL:	December 6, 2005
Last sequence update:	December 6, 2005
Last modified:	January 25, 2012
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)