Reviewed, UniProtKB/Swiss-Prot Q317J6 (SYN_DESDG)

Names and origin

Protein names

Recommended name:
    Asparaginyl-tRNA synthetase
    EC=6.1.1.22
Alternative name(s):
    Asparagine--tRNA ligase
      Short name=AsnRS

Gene names

Name:	asnS
Ordered Locus Names:	Dde_0099

Organism

Desulfovibrio desulfuricans (strain G20) [Complete proteome] [HAMAP]

Taxonomic identifier

207559 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio

Protein attributes

Sequence length	461 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + L-asparaginyl-tRNA(Asn). HAMAP MF_00534
Subunit structure	Homodimer By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00534
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	asparaginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP aspartyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP asparagine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP aspartate-tRNA ligase activity Inferred from electronic annotation. Source: InterPro nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 461	461	Asparaginyl-tRNA synthetase HAMAP MF_00534		PRO_1000051389

Sequences

	Sequence		Length	Mass (Da)
	Q317J6-1 [UniParc]. Last modified December 6, 2005. Version 1. Checksum: 57AAFD1740CAC90B	FASTA	461	51,878
	10 20 30 40 50 60 MKRTQILDAL NASAPCDDIR ICGWVRTRRD AKGFSFLELN DGSCLTNIQV IVDEETDAYR 70 80 90 100 110 120 SVGEATTGAS VDIRGQLVES PGKGQKWEVR AATMTLLGKA DPETFPLQKK RHSDEYLRTI 130 140 150 160 170 180 AHLRPRTNKF GAAFRIRAEA SYAVHSFFRE NGFFNVHTPI LTGSDCEGAG EMFRVTTLPA 190 200 210 220 230 240 VGASAPAEGS VFDGDFFGKE CSLTVSGQLE AEIMAQSLGK VYTFGPTFRA ENSNTPRHAA 250 260 270 280 290 300 EFWMVEPEMA FADLEDDMQL AEDMVKYVIS HVMKHCAADL DLFCKFVDKE LSARLENILA 310 320 330 340 350 360 HPFARVSYTE AIEILKASGR KFEYPAEWGA DLQTEHERYL AEEHFKKPVA VYDYPKEIKA 370 380 390 400 410 420 FYMRLNDDGK TVAAMDLLVP RIGELVGGSQ REERLDVLEA RIKELGQNPD DYWWYLELRK 430 440 450 460 FGTAPHAGFG MGFERLLMLL TGIGNIRDVI PFPRTPRHLE F

References

[1]

"Complete sequence of Desulfovibrio desulfuricans G20." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Goodwin L.A., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P. Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000112 Genomic DNA. Translation: ABB36900.1.
RefSeq	YP_386595.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q317J6.
Genome annotation databases
GeneID	3758841.
GenomeReviews	Gene locus Dde_0099 in contig CP000112_GR.
KEGG	dde:Dde_0099.
NMPDR	fig|207559.3.peg.755.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q317J6.
OMA	LQKKRHS.
Enzyme and pathway databases
BioCyc	DDES207559:DDE_0099-MON.
Family and domain databases
HAMAP	MF_00534. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II_cons-reg. IPR004522. Asn-tRNA-synth_IIb. IPR002312. Asp-tRNA-synth_IIb. IPR012340. NA-bd_OB-fold. IPR004365. NA_bd_OB_tRNA-helicase. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit.
Pfam	PF00152. tRNA-synt_2. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
PRINTS	PR01042. TRNASYNTHASP.
TIGRFAMs	TIGR00457. asnS. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYN_DESDG

Accession

Primary (citable) accession number: Q317J6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	December 6, 2005
Last modified:	November 3, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)