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Protein
Submitted name:

Uncharacterized protein

Gene

H2-Eb1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Keywordsi

Biological processImmunity

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:H2-Eb1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:95901. H2-Eb1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei225 – 247HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane, MHC IISAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_500421995526 – 263Sequence analysisAdd BLAST238

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi41 ↔ 105Combined sources
Glycosylationi45N-linked (GlcNAc...)Combined sources1
Disulfide bondi143 ↔ 199Combined sources

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiQ31163.
PeptideAtlasiQ31163.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1IEAX-ray2.30B/D29-224[»]
4P2OX-ray2.60B29-224[»]
4P2QX-ray3.30B/G/L/Q29-224[»]
4P2RX-ray3.29B/G/L/Q29-224[»]
ProteinModelPortaliQ31163.
SMRiQ31163.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini123 – 213Ig-likeInterPro annotationAdd BLAST91

Sequence similaritiesi

Belongs to the MHC class II family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410IWG3. Eukaryota.
ENOG410YI0S. LUCA.
HOVERGENiHBG012730.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.10.320.10. 1 hit.
InterProiView protein in InterPro
IPR007110. Ig-like_dom.
IPR036179. Ig-like_dom_sf.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR000353. MHC_II_b_N.
PfamiView protein in Pfam
PF07654. C1-set. 1 hit.
PF00969. MHC_II_beta. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD000328. MHC_II_b_N. 1 hit.
SMARTiView protein in SMART
SM00407. IGc1. 1 hit.
SM00921. MHC_II_beta. 1 hit.
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF54452. SSF54452. 1 hit.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q31163-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWLPRVPCVA AVILLLTVLS PPVALVRDSR PWFLEYCKSE CHFYNGTQRV
60 70 80 90 100
RLLVRYFYNL EENLRFDSDV GEFRAVTELG RPDAENWNSQ PEFLEQKRAE
110 120 130 140 150
VDTVCRHNYE IFDNFLVPRR VEPTVTVYPT KTQPLEHHNL LVCSVSDFYP
160 170 180 190 200
GNIEVRWFRN GKEEKTGIVS TGLVRNGDWT FQTLVMLETV PQSGEVYTCQ
210 220 230 240 250
VEHPSLTDPV TVEWKAQSTS AQNKMLSGVG GFVLGLLFLG AGLFIYFRNQ
260
KGQSGLQPTG LLS
Length:263
Mass (Da):30,011
Last modified:November 1, 1996 - v1
Checksum:iF5E40F56130A4E45
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M36939 mRNA. Translation: AAA39593.1.
PIRiA46561.
UniGeneiMm.22564.

Similar proteinsi

Entry informationi

Entry nameiQ31163_MOUSE
AccessioniPrimary (citable) accession number: Q31163
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: October 25, 2017
This is version 132 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources