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Protein
Submitted name:

H2-Ab1 protein

Gene

H2-Ab1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Keywordsi

Biological processImmunity

Names & Taxonomyi

Protein namesi
Submitted name:
H2-Ab1 proteinImported
Gene namesi
Name:H2-Ab1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:103070 H2-Ab1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei225 – 245HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, MHC IISAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_501430902128 – 263Sequence analysisAdd BLAST236

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi42 ↔ 104Combined sources
Glycosylationi46N-linked (GlcNAc...)Combined sources1
Disulfide bondi143 ↔ 199Combined sources

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

Protein-protein interaction databases

IntActiQ31135, 1 interactor

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1F3JX-ray3.10B/E31-217[»]
3CUPX-ray3.09B28-214[»]
3MBEX-ray2.89B/F28-214[»]
5DMKX-ray2.45B/D/F/H31-215[»]
6BLQX-ray1.80B21-217[»]
6BLRX-ray1.96B21-217[»]
6BLXX-ray2.32B21-217[»]
SMRiQ31135
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini123 – 211Ig-likeInterPro annotationAdd BLAST89

Sequence similaritiesi

Belongs to the MHC class II family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOVERGENiHBG012730

Family and domain databases

Gene3Di2.60.40.10, 1 hit
3.10.320.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003006 Ig/MHC_CS
IPR003597 Ig_C1-set
IPR011162 MHC_I/II-like_Ag-recog
IPR014745 MHC_II_a/b_N
IPR000353 MHC_II_b_N
PfamiView protein in Pfam
PF07654 C1-set, 1 hit
PF00969 MHC_II_beta, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD000328 MHC_II_b_N, 1 hit
SMARTiView protein in SMART
SM00407 IGc1, 1 hit
SM00921 MHC_II_beta, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
SSF54452 SSF54452, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
PS00290 IG_MHC, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q31135-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALQIPSLLL SAAVVVLMVL SSPGTEGGDS ERHFVHQFKG ECYFTNGTQR
60 70 80 90 100
IRLVTRYIYN REEYLRFDSD VGEYRAVTEL GRHSAEYYNK QYLERTRAEL
110 120 130 140 150
DTACRHNYEE TEVPTSLRRL EQPNVAISLS RTEALNHHNT LVCSVTDFYP
160 170 180 190 200
AKIKVRWFRN GQEETVGVSS TQLIRNGDWT FQVLVMLEMT PHQGEVYTCH
210 220 230 240 250
VEHPSLKSPI TVEWRAQSES ARSKMLSGIG GCVLGVIFLG LGLFIRHRSQ
260
KGPRGPPPAG LLQ
Length:263
Mass (Da):29,828
Last modified:November 1, 1996 - v1
Checksum:iBF790988F79547E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M15848 mRNA Translation: AAA39547.1
BC008168 mRNA Translation: AAH08168.1
AK155573 mRNA Translation: BAE33331.1
AK156899 mRNA Translation: BAE33890.1
AK171005 mRNA Translation: BAE42176.1
AK171211 mRNA Translation: BAE42316.1
AK171281 mRNA Translation: BAE42364.1
PIRiA25911
A27595
UniGeneiMm.254067

Similar proteinsi

Entry informationi

Entry nameiQ31135_MOUSE
AccessioniPrimary (citable) accession number: Q31135
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 171 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

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