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Protein
Submitted name:

Class II histocompatibility antigen, M beta 1 chain

Gene

H2-DMb1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Keywordsi

Biological processImmunity

Enzyme and pathway databases

ReactomeiR-MMU-2132295 MHC class II antigen presentation

Names & Taxonomyi

Protein namesi
Submitted name:
Class II histocompatibility antigen, M beta 1 chainImported
Submitted name:
H2-M beta1Imported
Submitted name:
Histocompatibility 2, class II, locus Mb1Imported
Submitted name:
MHC class II antigen Mb1Imported
Gene namesi
Name:H2-DMb1Imported
Synonyms:H2-DMb2Imported, H2-M beta1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:95922 H2-DMb1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei219 – 238HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane, MHC IISAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501509737521 – 261Sequence analysisAdd BLAST241

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000079547

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini115 – 204Ig-likeInterPro annotationAdd BLAST90

Sequence similaritiesi

Belongs to the MHC class II family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410IFNH Eukaryota
ENOG410YU9X LUCA
GeneTreeiENSGT00900000140849
HOVERGENiHBG007327
KOiK06752
OMAiNCASHTK
OrthoDBiEOG091G0G84
TreeFamiTF335727

Family and domain databases

Gene3Di2.60.40.10, 1 hit
3.10.320.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003006 Ig/MHC_CS
IPR003597 Ig_C1-set
IPR011162 MHC_I/II-like_Ag-recog
IPR014745 MHC_II_a/b_N
IPR000353 MHC_II_b_N
PfamiView protein in Pfam
PF07654 C1-set, 1 hit
PF00969 MHC_II_beta, 1 hit
SMARTiView protein in SMART
SM00407 IGc1, 1 hit
SM00921 MHC_II_beta, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
SSF54452 SSF54452, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
PS00290 IG_MHC, 1 hit

Sequencei

Sequence statusi: Complete.

Q31094-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAALWLLLLV LSLDCMGAGG FVAHVESTCV LDDAGTPQDF TYCVSFNKDL
60 70 80 90 100
LACWDPDVGK IVPCEFGVLY PWAENFSRIL NKEESLLQRL QNGLLDCASH
110 120 130 140 150
TQPFWNALTH RTRAPSVRVA QTTPFNTREP VMLACYVWGF YPADVTITWM
160 170 180 190 200
KNGQLVPSHS NKEKTAQPNG DWTYQTVSYL ALTPSYGDVY TCVVQHSGTS
210 220 230 240 250
EPIRGDWTPG LSPIQTVKVS VSAATLGLGF IIFCVGFFRW RKSHSSSYTP
260
LSGSTYPEGQ H
Length:261
Mass (Da):28,914
Last modified:August 1, 1999 - v2
Checksum:i50203DECC9E1888A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR974422 Genomic DNA No translation available.
AF100956 Genomic DNA Translation: AAC69909.1
BC003718 mRNA Translation: AAH03718.1
KJ650225 mRNA Translation: AIC84013.1
AK032745 mRNA Translation: BAC28006.1
RefSeqiNP_034517.2, NM_010387.3
UniGeneiMm.460938

Genome annotation databases

EnsembliENSMUST00000114232; ENSMUSP00000109870; ENSMUSG00000079547
GeneIDi14999
KEGGimmu:14999
UCSCiuc008cbq.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQ31094_MOUSE
AccessioniPrimary (citable) accession number: Q31094
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: August 1, 1999
Last modified: June 20, 2018
This is version 173 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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