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Protein
Submitted name:

Class II histocompatibility antigen, M beta 1 chain

Gene

H2-DMb1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Keywordsi

Biological processImmunity

Enzyme and pathway databases

ReactomeiR-MMU-2132295. MHC class II antigen presentation.

Names & Taxonomyi

Protein namesi
Submitted name:
Class II histocompatibility antigen, M beta 1 chainImported
Submitted name:
H2-M beta1Imported
Submitted name:
Histocompatibility 2, class II, locus Mb1Imported
Submitted name:
MHC class II antigen Mb1Imported
Gene namesi
Name:H2-DMb1Imported
Synonyms:H2-DMb2Imported, H2-M beta1Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:95922. H2-DMb1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei219 – 238HelicalSequence analysisAdd BLAST20

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, MHC IISAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501084309621 – 261Sequence analysisAdd BLAST241

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000079547.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini115 – 204Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST90

Sequence similaritiesi

Belongs to the MHC class II family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410IFNH. Eukaryota.
ENOG410YU9X. LUCA.
GeneTreeiENSGT00760000118970.
HOVERGENiHBG007327.
KOiK06752.
OMAiNCASHTK.
OrthoDBiEOG091G0G84.
TreeFamiTF335727.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.10.320.10. 1 hit.
InterProiView protein in InterPro
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR000353. MHC_II_b_N.
PfamiView protein in Pfam
PF07654. C1-set. 1 hit.
PF00969. MHC_II_beta. 1 hit.
SMARTiView protein in SMART
SM00407. IGc1. 1 hit.
SM00921. MHC_II_beta. 1 hit.
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF54452. SSF54452. 1 hit.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q31094-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAALWLLLLV LSLDCMGAGG FVAHVESTCV LDDAGTPQDF TYCVSFNKDL
60 70 80 90 100
LACWDPDVGK IVPCEFGVLY PWAENFSRIL NKEESLLQRL QNGLLDCASH
110 120 130 140 150
TQPFWNALTH RTRAPSVRVA QTTPFNTREP VMLACYVWGF YPADVTITWM
160 170 180 190 200
KNGQLVPSHS NKEKTAQPNG DWTYQTVSYL ALTPSYGDVY TCVVQHSGTS
210 220 230 240 250
EPIRGDWTPG LSPIQTVKVS VSAATLGLGF IIFCVGFFRW RKSHSSSYTP
260
LSGSTYPEGQ H
Length:261
Mass (Da):28,914
Last modified:August 1, 1999 - v2
Checksum:i50203DECC9E1888A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR974422 Genomic DNA. No translation available.
AF100956 Genomic DNA. Translation: AAC69909.1.
BC003718 mRNA. Translation: AAH03718.1.
KJ650225 mRNA. Translation: AIC84013.1.
AK032745 mRNA. Translation: BAC28006.1.
RefSeqiNP_034517.2. NM_010387.3.
UniGeneiMm.460938.

Genome annotation databases

EnsembliENSMUST00000114232; ENSMUSP00000109870; ENSMUSG00000079547.
GeneIDi14999.
KEGGimmu:14999.
UCSCiuc008cbq.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ31094_MOUSE
AccessioniPrimary (citable) accession number: Q31094
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: August 1, 1999
Last modified: August 30, 2017
This is version 163 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported