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Protein
Submitted name:

Major histocompatibility complex class I

Gene

Tap2

Organism
Mesocricetus auratus (Golden hamster)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi503 – 510ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-bindingPROSITE-ProRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Major histocompatibility complex class IImported
Submitted name:
antigen peptide transporter 2 precursorImported
Gene namesi
Name:Tap2Imported
OrganismiMesocricetus auratus (Golden hamster)Imported
Taxonomic identifieri10036 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaCricetidaeCricetinaeMesocricetus
Proteomesi
  • UP000189706 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei49 – 77HelicalSequence analysisAdd BLAST29
Transmembranei149 – 169HelicalSequence analysisAdd BLAST21
Transmembranei189 – 216HelicalSequence analysisAdd BLAST28
Transmembranei270 – 288HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_500999357826 – 703Sequence analysisImportedAdd BLAST678

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini154 – 435ABC transmembrane type-1InterPro annotationAdd BLAST282
Domaini468 – 702ABC transporterInterPro annotationAdd BLAST235

Keywords - Domaini

SignalSequence analysisImported, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG008358.
OrthoDBiEOG091G05Q7.

Family and domain databases

Gene3Di1.20.1560.10. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR036640. ABC1_TM_sf.
IPR013305. ABC_Tap-like.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
IPR005293. Tap2/ABCB3.
PfamiView protein in Pfam
PF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
PRINTSiPR01897. TAP2PROTEIN.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 1 hit.
TIGRFAMsiTIGR00958. 3a01208. 1 hit.
PROSITEiView protein in PROSITE
PS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q31090-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALSYLRPWA SLLLVDMALL ALLQGSPGNL LPLGLPGLWL EGTLRLGGLW
60 70 80 90 100
GLLAVGGLLG RVGTFPPLLC LATPLFFSLR ALVGGTMSSP AVRVASASWV
110 120 130 140 150
WLLADYKAAA LGWAVWAVLS PPGAREKEAG QEKNKSLMWQ LLRLSRPDLP
160 170 180 190 200
FLMVAFFFLA WAVLGETLIP HYSGRVIDIL GSDFDPXSFA SAIFFMCLFS
210 220 230 240 250
VGSSLSAGCR GGSFLFTMSR INLRIRERLF SSLLRQDLGF FQENKTGELN
260 270 280 290 300
SRLSSDTSKM SRWLPYNANI LLRSLVKVIG LYCFMLQVSP RLTFLSLLDL
310 320 330 340 350
PLTIAAEKVY NPRHQAVLTE IQDATAKAGQ VVREAVGGLQ TVRSFGAEEQ
360 370 380 390 400
EVSRYKEALE RCRQLWWRRD LERALYLAIR RVMALGMQVL ILNCGVQQIL
410 420 430 440 450
AGEVTRGGLL SFLLYQEEVG DYVRNLVYMY GDMLSNVGAA EKVFCYIDRK
460 470 480 490 500
PNLPQPGTLA PSRLEGRVEF QDVTFSYPSR PXKPVLKGLT FTLHPGKVTA
510 520 530 540 550
LVGPNGSGKS TVAAPLQNLY QPTGGQLLLD GQPLVQYDHH YLHRQVVLVG
560 570 580 590 600
QEPVLFSGSV KDNIAYGLKD CEDAQVMAAV RAACADDFIG EMPDGIHTEI
610 620 630 640 650
GEKGSQLAVG QKQRLAIARA LVRNPRVLIL DEATSALDSQ CEQALQAWRS
660 670 680 690 700
KGDRTVLVIA HRLHTVQNVD QVLVLKQGQL VEHSQLREDQ DVYAHLVQQR

LEA
Length:703
Mass (Da):77,579
Last modified:November 1, 1996 - v1
Checksum:i75AD056EDF95102A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42939 mRNA. Translation: AAA96713.1.
RefSeqiNP_001268532.1. NM_001281603.1.

Genome annotation databases

GeneIDi101835124.

Similar proteinsi

Entry informationi

Entry nameiQ31090_MESAU
AccessioniPrimary (citable) accession number: Q31090
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: October 25, 2017
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported