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Q31065 (Q31065_PIG) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 99. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
MHC class II DR-alpha EMBL AAA31075.1
Submitted name:
MHC class II antigen EMBL AAO63765.1
Submitted name:
MHC class II antigen DR-alpha EMBL ABK96887.1
Gene names
Name:SLA-DR-alpha EMBL AAA31075.1
Synonyms:SLA-DRA EMBL ABI31830.1, SLA-DRA1 EMBL AAO63765.1
OrganismSus scrofa (Pig) EMBL AAA31075.1
Taxonomic identifier9823 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Cetartiodactyla › Suina › Suidae › Sus

Protein attributes

Sequence length252 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the MHC class II family. RuleBase RU004238

Contains 1 Ig-like C1-type (immunoglobulin-like) domain. SAAS SAAS003597

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Potential EMBL AAA31075.1
Chain23 – 252230MHC class II DR-alpha EMBL AAA31075.1
PRO_5000143831

Sequences

Sequence LengthMass (Da)Tools
Q31065 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: F47D022AB8D44A82

FASTA25228,382
        10         20         30         40         50         60 
MTILGVPVLG FVITILNLQK SWAIVENHVI IQAEFYLSPD KSGEFMFDFD GDEIFHVDME 

        70         80         90        100        110        120 
KRETVWRLEE FGHFASFEAQ GALANIAVDK ANLEILIKRS NNTPNTNVPP EVTVLSDKPV 

       130        140        150        160        170        180 
ELGEPNILIC FIDKFSPPVV NVTWLRNGSP VTRGVSETVF LPREDHLFRK FHYLPFMPST 

       190        200        210        220        230        240 
EDVYDCQVEH WGLDKPLLKH WEFEAQTPLP ETTENTVCAL GLIVALVGII VGTVLIIKGV 

       250 
RKGNATERRG PL

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References

[1]"Structure and expression of class II alpha genes in miniature swine."
Hirsch F., Germana S., Gustafsson K., Pratt K., Sachs D.H., Leguern C.
J. Immunol. 149:841-846(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Minnesota miniature swine EMBL AAA31075.1.
Tissue: Spleen and blood EMBL AAA31075.1.
[2]"Nomenclature for factors of the SLA class-I system, 2004."
Smith D.M., Lunney J.K., Martens G.W., Ando A., Lee J.H., Ho C.S., Schook L., Renard C., Chardon P.
Tissue Antigens 65:136-149(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[3]"Characterization and clone of Hunan Shaziling pig DR gene."
Tang Y., Xing X., Wang W.
Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Ear EMBL ABK96887.1.
[4]"Sequence-based characterization of the eight SLA loci in Korean native pigs."
Lee Y.J., Cho K.H., Kim M.J., Smith D.M., Ho C.S., Jung K.C., Jin D.I., Park C.S., Jeon J.T., Lee J.H.
Int. J. Immunogenet. 35:333-334(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[5]"Sequence base SLA typing in CMS miniature pig."
Yeom S.C., Park C.G., Lee B.C., Lee W.J.
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[6]"cDNA cloning, genomic structure and genetic polymorphism of swine MHC class I and II genes in Chinese mini pig."
Mo S., Jing Z., Fang Y., Feng H.
Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		M93028 mRNA. Translation: AAA31075.1.
AY247783 mRNA. Translation: AAO63765.1.
AY285926 mRNA. Translation: AAP37550.1.
AY285935 mRNA. Translation: AAP37559.1.
AY285937 mRNA. Translation: AAP37561.1.
DQ883223 mRNA. Translation: ABI31830.1.
EF143987 mRNA. Translation: ABK96887.1.
EU722918 mRNA. Translation: ACE07020.1.
FJ905836 Genomic DNA. Translation: ADB82916.1.
PIRA46505.
RefSeqNP_001107178.1. NM_001113706.1.
UniGeneSsc.222.

3D structure databases

HSSPHSSP built from PDB template 1HQR based on UniProtKB P01903.
ProteinModelPortalQ31065.
SMRQ31065. Positions 26-205.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID100135040.
KEGGssc:100135040.

Organism-specific databases

CTD100135040.

Phylogenomic databases

HOVERGENHBG006862.
KOK06752.

Family and domain databases

Gene3D2.60.40.10. 1 hit.
3.10.320.10. 1 hit.
InterProIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR001003. MHC_II_a_N.
[Graphical view]
PfamPF07654. C1-set. 1 hit.
PF00993. MHC_II_alpha. 1 hit.
[Graphical view]
SMARTSM00407. IGc1. 1 hit.
SM00920. MHC_II_alpha. 1 hit.
[Graphical view]
SUPFAMSSF54452. MHC_I/II-like_Ag-recog. 1 hit.
PROSITEPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ31065_PIG
AccessionPrimary (citable) accession number: Q31065
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: April 3, 2013
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info