Q30ZR5 (SYGA_DESDG) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycine--tRNA ligase alpha subunit
EC=6.1.1.14

Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	Dde_2034

Organism

Desulfovibrio desulfuricans (strain G20) [Complete proteome] [HAMAP]

Taxonomic identifier

207559 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio

Protein attributes

Sequence length	294 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm HAMAP MF_00254.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glycine-tRNA ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 294	294	Glycine--tRNA ligase alpha subunit HAMAP MF_00254		PRO_1000047413

Sequences

	Sequence		Length	Mass (Da)
	Q30ZR5 [UniParc]. Last modified December 6, 2005. Version 1. Checksum: 019AD14919F9E0A9	FASTA	294	34,015
	10 20 30 40 50 60 MNFQDVILTL QNFWARRGCA IQQPFDSECG AGTFNPATFL RVIGPEPWNV AYVEPSRRPT 70 80 90 100 110 120 DGRYGENPNR LQHYFQFQVI LKPSPDNVQE IYIDSLRALG INPAEHDIRF VEDDWESPTL 130 140 150 160 170 180 GAWGLGWEVW LNGMEVTQFT YFQQVGGIDL SPTSVEITYG LERLCMYLQE KESVYDLMWN 190 200 210 220 230 240 DTVTYGHIYH RNEVEMSRYN FEESDAGMLL ELFNAYEREC TRLCEKQLLW PAYDYCLKCS 250 260 270 280 290 HTFNLLDARG AISITERTGY IGRVRVLASS VARLYAAQRE EMGYPMLNTG IRKG

References

[1]

"Complete sequence of Desulfovibrio desulfuricans G20." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Goodwin L.A., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P. Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: G20.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000112 Genomic DNA. Translation: ABB38831.1.
RefSeq	YP_388526.1. NC_007519.1.
3D structure databases
HSSP	HSSP built from PDB template 1J5W based on UniProtKB Q9WY59.
ProteinModelPortal	Q30ZR5.
SMR	Q30ZR5. Positions 1-275.
ModBase	Search...
Protein-protein interaction databases
STRING	Q30ZR5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3757042.
GenomeReviews	Gene locus Dde_2034 in contig CP000112_GR.
KEGG	dde:Dde_2034.
NMPDR	fig|207559.3.peg.2317.
PATRIC	21742999. VBIDesDes50040_2010.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0752.
HOGENOM	HBG285316.
OMA	CRRPTDG.
ProtClustDB	PRK09348.
Enzyme and pathway databases
BioCyc	DDES207559:DDE_2034-MONOMER.
Family and domain databases
HAMAP	MF_00254. Gly_tRNA_synth_alpha. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
KO	K01878.
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
TIGRFAMs	TIGR00388. GlyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_DESDG

Accession

Primary (citable) accession number: Q30ZR5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	December 6, 2005
Last modified:	January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program