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Q30UH8 (UPPP_SULDN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:Suden_0072
OrganismSulfurimonas denitrificans (strain ATCC 33889 / DSM 1251) (Thiomicrospira denitrificans (strain ATCC 33889 / DSM 1251)) [Complete proteome] [HAMAP]
Taxonomic identifier326298 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeSulfurimonas

Protein attributes

Sequence length256 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 256256Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000227646

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane39 – 5921Helical; Potential
Transmembrane70 – 9021Helical; Potential
Transmembrane97 – 11721Helical; Potential
Transmembrane134 – 15421Helical; Potential
Transmembrane176 – 19621Helical; Potential
Transmembrane205 – 22521Helical; Potential
Transmembrane235 – 25521Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q30UH8 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: 14E4BD25E973F12F

FASTA25628,561
        10         20         30         40         50         60 
MTILDSIILG AIEGFTEFLP ISSTGHLIVA SEFLGLEQNA INKAYEVIIQ FSAILAVIFN 

        70         80         90        100        110        120 
YKDKFSIKKI DLWMKVFIAF LPLAIIGFIF STQIKELFSL HVVAVMFIVG GVVFLIVEKF 

       130        140        150        160        170        180 
FINEDEKTIY EVEAISLKQS LIIGFAQIFA LIPGTSRAGS TIIGALLVGL SRKASAEFSF 

       190        200        210        220        230        240 
LLAFPVMGAV TAYDLLKHYK DFSEANLIIL GVGFVTSFVV AYLSIKLFLK FLEKFTFFFF 

       250 
GVYRIVFGVI LLLFFN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000153 Genomic DNA. Translation: ABB43353.1.
RefSeqYP_392588.1. NC_007575.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING326298.Suden_0072.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABB43353; ABB43353; Suden_0072.
GeneID3763210.
KEGGtdn:Suden_0072.
PATRIC23768604. VBISulDen68967_0075.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAFNDAHAK.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycSDEN326298:GH9P-77-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUPPP_SULDN
AccessionPrimary (citable) accession number: Q30UH8
Entry history
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: December 6, 2005
Last modified: May 14, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families