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Q30SG7 (TRMB_SULDN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
tRNA (guanine-N(7)-)-methyltransferase

EC=2.1.1.33
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase
tRNA(m7G46)-methyltransferase
Gene names
Name:trmB
Ordered Locus Names:Suden_0785
OrganismSulfurimonas denitrificans (strain ATCC 33889 / DSM 1251) (Thiomicrospira denitrificans (strain ATCC 33889 / DSM 1251)) [Complete proteome] [HAMAP]
Taxonomic identifier326298 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeSulfurimonas

Protein attributes

Sequence length390 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity. HAMAP-Rule MF_01057

Catalytic activity

S-adenosyl-L-methionine + guanine46 in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine46 in tRNA. HAMAP-Rule MF_01057

Pathway

tRNA modification; N(7)-methylguanine-tRNA biosynthesis. HAMAP-Rule MF_01057

Sequence similarities

Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.

Ontologies

Keywords
   Biological processtRNA processing
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functiontRNA (guanine-N7-)-methyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 390390tRNA (guanine-N(7)-)-methyltransferase HAMAP-Rule MF_01057
PRO_0000229208

Sites

Binding site1281S-adenosyl-L-methionine By similarity
Binding site1531S-adenosyl-L-methionine By similarity
Binding site1801S-adenosyl-L-methionine By similarity
Binding site2061Substrate By similarity
Binding site2361Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q30SG7 [UniParc].

Last modified December 6, 2005. Version 1.
Checksum: F8E8801AEFE94201

FASTA39045,297
        10         20         30         40         50         60 
MPHLHIAEFK EVEIPSSKDG VSFNFIAKNS SHQEEKLISI TVDEDEFFLL AIDENSKKLL 

        70         80         90        100        110        120 
KSDKLTRPPS IFNVHKALLS YASATCMNII SSNVPQNQKN IHLREVKALK DINYFATTFP 

       130        140        150        160        170        180 
KKEKICIEVG FGSGRHLLHQ AQNNPNILYI GIEIHTPSIE QLLKQISIKN IENILVLNYD 

       190        200        210        220        230        240 
ARLFMELVPS NKIDKIYVHF PVPWDKKPHR RVISTAFIEE ARRILNIGGT LELRTDSENY 

       250        260        270        280        290        300 
YAYSYETFIA FEKTTLHINK NRDIAITSKY EDRWKRMQKN FYDVTMINSE ESPELSLEGD 

       310        320        330        340        350        360 
FNFSHVKLNT QEVINLYKKT QKFDSGFINF ERSYFLDDGA MLRVSMGNFD KPEHLYVIVK 

       370        380        390 
ENKAYYYPKT PLRSKSNLMA HKLLNGVLCE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000153 Genomic DNA. Translation: ABB44064.1.
RefSeqYP_393299.1. NC_007575.1.

3D structure databases

ProteinModelPortalQ30SG7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING326298.Suden_0785.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABB44064; ABB44064; Suden_0785.
GeneID3764286.
KEGGtdn:Suden_0785.
PATRIC23770140. VBISulDen68967_0812.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0220.
HOGENOMHOG000252163.
KOK03439.
OMASKYEARW.
OrthoDBEOG6K6VBC.
ProtClustDBPRK14121.

Enzyme and pathway databases

BioCycSDEN326298:GH9P-825-MONOMER.
UniPathwayUPA00989.

Family and domain databases

HAMAPMF_01057. tRNA_methyltr_TrmB.
InterProIPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamPF02390. Methyltransf_4. 1 hit.
[Graphical view]
TIGRFAMsTIGR00091. TIGR00091. 1 hit.
PROSITEPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTRMB_SULDN
AccessionPrimary (citable) accession number: Q30SG7
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: December 6, 2005
Last modified: April 16, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways