Q30S50 (Q30S50_SULDN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL ABB44181.1
EC=2.4.1.182 EMBL ABB44181.1

Gene names

Ordered Locus Names:

Suden_0903

Organism

Sulfurimonas denitrificans (strain ATCC 33889 / DSM 1251) (Thiomicrospira denitrificans (strain ATCC 33889 / DSM 1251)) [Complete proteome] [HAMAP]

Taxonomic identifier

326298 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Sulfurimonas

Protein attributes

Sequence length	348 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 EMBL ABB44181.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q30S50 [UniParc]. Last modified December 6, 2005. Version 1. Checksum: 61F5823DB248A501	FASTA	348	39,795
	10 20 30 40 50 60 MKILVSALEH SANIHLKSLK KELSSDVEFI GIFDRDLGES IVDLRALAIM GFVDAIKKLF 70 80 90 100 110 120 FFIKLNNEML NLAKDVDKVL LIDSSGFNLP LAKKIKKKYP NKEIIYYILP QAWAWKKKRI 130 140 150 160 170 180 PILEKTIDHL ASILPFEKDY YSKTAPITYV GHPLLDQICE FKETLREEVK KIVFMPGSRK 190 200 210 220 230 240 AEIKKLLPIF RELQKKLDAE SIIIIPKHFS KEDIKEVYGN LAGFKIAYET HETLLEADFA 250 260 270 280 290 300 FICSGTATLE ASLIGTPFIL TFIAKGLDYF IASRLVKLEH IGLANIMFSK FKDGVLHPEF 310 320 330 340 IQKDVTLENL LKSYNEYDRE KFLSDSKSLR GYLKHGSSKT VAKIVEKS

References

[1]

"Genome of the epsilonproteobacterial chemolithoautotroph Sulfurimonas denitrificans." Sievert S.M., Scott K.M., Klotz M.G., Chain P.S.G., Hauser L.J., Hemp J., Huegler M., Land M., Lapidus A., Larimer F.W., Lucas S., Malfatti S.A., Meyer F., Paulsen I.T., Ren Q., Simon J., Bailey K., Diaz E. , Fitzpatrick K.A., Glover B., Gwatney N., Korajkic A., Long A., Mobberley J.M., Pantry S.N., Pazder G., Peterson S., Quintanilla J.D., Sprinkle R., Stephens J., Thomas P., Vaughn R., Weber M.J., Wooten L.L. Appl. Environ. Microbiol. 74:1145-1156(2008) [PubMed: 18065616] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000153 Genomic DNA. Translation: ABB44181.1.
RefSeq	YP_393416.1. NC_007575.1.
3D structure databases
ProteinModelPortal	Q30S50.
ModBase	Search...
Protein-protein interaction databases
STRING	Q30S50.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3764077.
GenomeReviews	Gene locus Suden_0903 in contig CP000153_GR.
KEGG	tdn:Suden_0903.
NMPDR	fig|326298.3.peg.1244.
PATRIC	23770386. VBISulDen68967_0934.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0763.
HOGENOM	HBG584837.
OMA	IGLANIM.
ProtClustDB	PRK14089.
Enzyme and pathway databases
BioCyc	TDEN326298:TMDEN_0903-MONOMER.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q30S50_SULDN

Accession

Primary (citable) accession number: Q30S50

Entry history

Integrated into UniProtKB/TrEMBL:	December 6, 2005
Last sequence update:	December 6, 2005
Last modified:	December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)