Q30RQ6 (Q30RQ6_SULDN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Isocitrate dehydrogenase (NADP+) EMBL ABB44325.1
EC=1.1.1.42 EMBL ABB44325.1

Gene names

Ordered Locus Names:

Suden_1047

Organism

Sulfurimonas denitrificans (strain ATCC 33889 / DSM 1251) (Thiomicrospira denitrificans (strain ATCC 33889 / DSM 1251)) [Complete proteome] [HAMAP] EMBL ABB44325.1

Taxonomic identifier

326298 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Sulfurimonas › Sulfurimonas denitrificans

Protein attributes

Sequence length	729 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. PIRSR PIRSR009407-3

Ontologies

Keywords
Ligand	Magnesium PIRSR PIRSR009407-3 Metal-binding PIRSR PIRSR009407-3
Molecular function	Oxidoreductase EMBL ABB44325.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	isocitrate dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Region	130 – 137	8	Substrate binding By similarity PIRSR PIRSR009407-2
Sites
	Metal binding	341	1	Magnesium or manganese By similarity PIRSR PIRSR009407-3
	Metal binding	538	1	Magnesium or manganese By similarity PIRSR PIRSR009407-3
	Metal binding	542	1	Magnesium or manganese By similarity PIRSR PIRSR009407-3
	Binding site	143	1	Substrate By similarity PIRSR PIRSR009407-2
	Binding site	537	1	Substrate By similarity PIRSR PIRSR009407-2
	Site	248	1	Critical for catalysis By similarity PIRSR PIRSR009407-1
	Site	411	1	Critical for catalysis By similarity PIRSR PIRSR009407-1

Sequences

	Sequence		Length	Mass (Da)
	Q30RQ6 [UniParc]. Last modified December 6, 2005. Version 1. Checksum: DEA21B28EE41B0D5	FASTA	729	79,562
	10 20 30 40 50 60 MSKIIWSKID EAPALATYSL LPIVNAFTKA AGVEVVTSDI SLAGRVISKF SDRLKPEQRI 70 80 90 100 110 120 NDELAELGNV VLQPDGNIIK LPNISASVGQ LIECITELQA QGYDVPNYPE DAKTDEEKAL 130 140 150 160 170 180 KEIYSTCLGS AVNPVLREGN SDRRAAAAVK RFAQKNPHKL RAFESPSKAY VAHMNGGDFF 190 200 210 220 230 240 SNEKSVIVEG NAPVTIELNG KVLKTLNDVV DKEIMDATFM SAKALQAFYQ KTLDDAKKNG 250 260 270 280 290 300 VLWSLHLKAT MMKVSDPIMF GHAVKVFFKD VFAKYGDELT AIGYNANMGL GDLYKKLEKS 310 320 330 340 350 360 SKKAEIIAAI EATYDIQPPM AMVDSDKGIT NLHASNDIII DASMPVVVRD GGKMWNRDGK 370 380 390 400 410 420 VQECVSVIPD ASYAFFHKAM VDDCVANGQY DVTTMGNVAN VGLMAQKAEE YGSHPTTFEI 430 440 450 460 470 480 AENGSVEVKQ NGKVLMSHNV EAGDIWRMSR VKDIPIQDWV RLAVERARLT GSPAVFWLDK 490 500 510 520 530 540 NRAHDANMIK KVNEYLKNHD TTGLELPIMD VASAAKYTNA RVRKGEDTIS VTGNVLRDHL 550 560 570 580 590 600 TDMYPILELG TSAKMLSIVP LLAGGGVFET GAGGSAPKHV DQFLEEGHLR WDSLGEFLAL 610 620 630 640 650 660 AESLRFIAQK NSDDKLAAVT TALDIANAAY LDNNKAPSRK AGEPDNKASH FFLAQYWAKA 670 680 690 700 710 720 LSEGKNAELA AKFAPIAKAL TENEAKIIEE LLSIEGKAQD IGGYYHPDDK KAEAAMRPSA TLNKIVDSI

References

[1]

"Genome of the epsilonproteobacterial chemolithoautotroph Sulfurimonas denitrificans." Sievert S.M., Scott K.M., Klotz M.G., Chain P.S.G., Hauser L.J., Hemp J., Huegler M., Land M., Lapidus A., Larimer F.W., Lucas S., Malfatti S.A., Meyer F., Paulsen I.T., Ren Q., Simon J., Bailey K., Diaz E. , Fitzpatrick K.A., Glover B., Gwatney N., Korajkic A., Long A., Mobberley J.M., Pantry S.N., Pazder G., Peterson S., Quintanilla J.D., Sprinkle R., Stephens J., Thomas P., Vaughn R., Weber M.J., Wooten L.L. Appl. Environ. Microbiol. 74:1145-1156(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33889 / DSM 1251.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000153 Genomic DNA. Translation: ABB44325.1.
RefSeq	YP_393560.1. NC_007575.1.
3D structure databases
ProteinModelPortal	Q30RQ6.
SMR	Q30RQ6. Positions 2-729.
ModBase	Search...
Protein-protein interaction databases
STRING	326298.Suden_1047.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABB44325; ABB44325; Suden_1047.
GeneID	3763931.
KEGG	tdn:Suden_1047.
PATRIC	23770696. VBISulDen68967_1088.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2838.
HOGENOM	HOG000240860.
KO	K00031.
OMA	PRTMGTV.
ProtClustDB	CLSK867411.
Enzyme and pathway databases
BioCyc	SDEN326298:GH9P-1106-MONOMER.
Family and domain databases
Gene3D	3.40.718.10. 3 hits.
InterPro	IPR004436. Isocitrate_DH_NADP_mono. IPR024084. IsoPropMal-DH-like_dom. [Graphical view]
Pfam	PF03971. IDH. 1 hit. [Graphical view]
PIRSF	PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMs	TIGR00178. monomer_idh. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q30RQ6_SULDN

Accession

Primary (citable) accession number: Q30RQ6

Entry history

Integrated into UniProtKB/TrEMBL:	December 6, 2005
Last sequence update:	December 6, 2005
Last modified:	May 1, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)