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Q30RQ6

- Q30RQ6_SULDN

UniProt

Q30RQ6 - Q30RQ6_SULDN

Protein
Submitted name:

Isocitrate dehydrogenase (NADP+)

Gene

Suden_1047

Organism
Sulfurimonas denitrificans (strain ATCC 33889 / DSM 1251) (Thiomicrospira denitrificans (strain ATCC 33889 / DSM 1251))
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (06 Dec 2005)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei143 – 1431SubstrateUniRule annotation
    Sitei248 – 2481Critical for catalysisUniRule annotation
    Metal bindingi341 – 3411Magnesium or manganese
    Sitei411 – 4111Critical for catalysisUniRule annotation
    Binding sitei537 – 5371SubstrateUniRule annotation
    Metal bindingi538 – 5381Magnesium or manganese
    Metal bindingi542 – 5421Magnesium or manganese

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciSDEN326298:GH9P-1089-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase (NADP+)Imported (EC:1.1.1.42Imported)
    Gene namesi
    Ordered Locus Names:Suden_1047Imported
    OrganismiSulfurimonas denitrificans (strain ATCC 33889 / DSM 1251) (Thiomicrospira denitrificans (strain ATCC 33889 / DSM 1251))Imported
    Taxonomic identifieri326298 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeSulfurimonas
    ProteomesiUP000002714: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi326298.Suden_1047.

    Structurei

    3D structure databases

    ProteinModelPortaliQ30RQ6.
    SMRiQ30RQ6. Positions 2-729.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni130 – 1378Substrate bindingUniRule annotation

    Phylogenomic databases

    eggNOGiCOG2838.
    HOGENOMiHOG000240860.
    KOiK00031.
    OMAiEEQRIGD.
    OrthoDBiEOG6DVJPP.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q30RQ6-1 [UniParc]FASTAAdd to Basket

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    MSKIIWSKID EAPALATYSL LPIVNAFTKA AGVEVVTSDI SLAGRVISKF    50
    SDRLKPEQRI NDELAELGNV VLQPDGNIIK LPNISASVGQ LIECITELQA 100
    QGYDVPNYPE DAKTDEEKAL KEIYSTCLGS AVNPVLREGN SDRRAAAAVK 150
    RFAQKNPHKL RAFESPSKAY VAHMNGGDFF SNEKSVIVEG NAPVTIELNG 200
    KVLKTLNDVV DKEIMDATFM SAKALQAFYQ KTLDDAKKNG VLWSLHLKAT 250
    MMKVSDPIMF GHAVKVFFKD VFAKYGDELT AIGYNANMGL GDLYKKLEKS 300
    SKKAEIIAAI EATYDIQPPM AMVDSDKGIT NLHASNDIII DASMPVVVRD 350
    GGKMWNRDGK VQECVSVIPD ASYAFFHKAM VDDCVANGQY DVTTMGNVAN 400
    VGLMAQKAEE YGSHPTTFEI AENGSVEVKQ NGKVLMSHNV EAGDIWRMSR 450
    VKDIPIQDWV RLAVERARLT GSPAVFWLDK NRAHDANMIK KVNEYLKNHD 500
    TTGLELPIMD VASAAKYTNA RVRKGEDTIS VTGNVLRDHL TDMYPILELG 550
    TSAKMLSIVP LLAGGGVFET GAGGSAPKHV DQFLEEGHLR WDSLGEFLAL 600
    AESLRFIAQK NSDDKLAAVT TALDIANAAY LDNNKAPSRK AGEPDNKASH 650
    FFLAQYWAKA LSEGKNAELA AKFAPIAKAL TENEAKIIEE LLSIEGKAQD 700
    IGGYYHPDDK KAEAAMRPSA TLNKIVDSI 729
    Length:729
    Mass (Da):79,562
    Last modified:December 6, 2005 - v1
    Checksum:iDEA21B28EE41B0D5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000153 Genomic DNA. Translation: ABB44325.1.
    RefSeqiYP_393560.1. NC_007575.1.

    Genome annotation databases

    EnsemblBacteriaiABB44325; ABB44325; Suden_1047.
    GeneIDi3763931.
    KEGGitdn:Suden_1047.
    PATRICi23770696. VBISulDen68967_1088.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000153 Genomic DNA. Translation: ABB44325.1 .
    RefSeqi YP_393560.1. NC_007575.1.

    3D structure databases

    ProteinModelPortali Q30RQ6.
    SMRi Q30RQ6. Positions 2-729.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 326298.Suden_1047.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABB44325 ; ABB44325 ; Suden_1047 .
    GeneIDi 3763931.
    KEGGi tdn:Suden_1047.
    PATRICi 23770696. VBISulDen68967_1088.

    Phylogenomic databases

    eggNOGi COG2838.
    HOGENOMi HOG000240860.
    KOi K00031.
    OMAi EEQRIGD.
    OrthoDBi EOG6DVJPP.

    Enzyme and pathway databases

    BioCyci SDEN326298:GH9P-1089-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33889 / DSM 1251Imported.

    Entry informationi

    Entry nameiQ30RQ6_SULDN
    AccessioniPrimary (citable) accession number: Q30RQ6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 6, 2005
    Last sequence update: December 6, 2005
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3