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Protein

Putative beta-defensin 109B

Gene

DEFB109B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

Has antibacterial activity.By similarity

GO - Biological processi

Keywordsi

Molecular functionAntibiotic, Antimicrobial, Defensin

Enzyme and pathway databases

ReactomeiR-HSA-1461957. Beta defensins.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative beta-defensin 109B
Alternative name(s):
Defensin, beta 109, pseudogene 1B
Defensin, beta 109BImported
Gene namesi
Name:DEFB109BImported
Synonyms:DEFB109P1B
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:33469. DEFB109B.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Polymorphism and mutation databases

DMDMi84028868.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000004533323 – 87Putative beta-defensin 109BAdd BLAST65

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi31 ↔ 59By similarity
Disulfide bondi38 ↔ 53By similarity
Disulfide bondi43 ↔ 60By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PeptideAtlasiQ30KR1.
PRIDEiQ30KR1.

Structurei

3D structure databases

ProteinModelPortaliQ30KR1.
SMRiQ30KR1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the beta-defensin family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOVERGENiHBG081406.
InParanoidiQ30KR1.
PhylomeDBiQ30KR1.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q30KR1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLHLLLLIL LLFSILLSPV RGGLGPAEGH CLNLFGVCRT DVCNIVEDQI
60 70 80
GACRRRMKCC RAWWILMPIP TPLIMSDYQE PLKPNLK
Length:87
Mass (Da):9,886
Last modified:December 6, 2005 - v1
Checksum:iF9C501C495B608ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ012013 mRNA. Translation: AAY59749.1.
UniGeneiHs.616079.
Hs.721640.

Similar proteinsi

Entry informationi

Entry nameiDB109_HUMAN
AccessioniPrimary (citable) accession number: Q30KR1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: December 6, 2005
Last modified: October 25, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families