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Protein

Beta-defensin

Gene

Defb26

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Has antibacterial activity.UniRule annotation

GO - Biological processi

Keywordsi

Molecular functionAntibioticUniRule annotationSAAS annotation, Antimicrobial, DefensinUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-MMU-1461957 Beta defensins
R-MMU-1461973 Defensins

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-defensinUniRule annotation
Gene namesi
Name:Defb26Imported
Synonyms:EG654457Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:3643488 Defb26

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedUniRule annotationSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15Sequence analysisAdd BLAST15
ChainiPRO_501509737116 – 186Beta-defensinSequence analysisAdd BLAST171

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000074680

Family & Domainsi

Sequence similaritiesi

Belongs to the beta-defensin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410J47E Eukaryota
ENOG4111802 LUCA
GeneTreeiENSGT00390000000604
HOGENOMiHOG000115943
HOVERGENiHBG051308
OrthoDBiEOG091G16Z6

Family and domain databases

InterProiView protein in InterPro
IPR025933 Beta_defensin
PANTHERiPTHR15001 PTHR15001, 1 hit
PfamiView protein in Pfam
PF13841 Defensin_beta_2, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD866254 PD866254, 1 hit

Sequencei

Sequence statusi: Complete.

Q30KN7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIFLTLAFIV HGLLTQGNKA AWRRPIPKCW KNSLGYCRVR CQEEERYIYL
60 70 80 90 100
CKNKVSCCIH RTLSEDKLPS GPPIHTVTRV IPSFNIPVNS SATRLTDNWD
110 120 130 140 150
ANDSKTPIGT IVNPAGIGKT PTGTTVNPAG IGKMPTGTTV NPAGIGKTPT
160 170 180
GTTVNPAGIG KTPTTTTPIY SWATNTKPFT MMPNTT
Length:186
Mass (Da):20,056
Last modified:December 6, 2005 - v1
Checksum:iB06D9817CC4C5F38
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844517 Genomic DNA No translation available.
BC139131 mRNA Translation: AAI39132.1
DQ012037 mRNA Translation: AAY59773.1
RefSeqiNP_001034209.1, NM_001039120.2
UniGeneiMm.389363

Genome annotation databases

EnsembliENSMUST00000099205; ENSMUSP00000096811; ENSMUSG00000074680
GeneIDi654457
KEGGimmu:654457
UCSCiuc008nfo.2 mouse

Entry informationi

Entry nameiQ30KN7_MOUSE
AccessioniPrimary (citable) accession number: Q30KN7
Entry historyiIntegrated into UniProtKB/TrEMBL: December 6, 2005
Last sequence update: December 6, 2005
Last modified: June 20, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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