Q30CR9 (Q30CR9_STRAU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
LipPks4 EMBL ABB05105.1

Gene names

Name:

lipPks4 EMBL ABB05105.1

Organism

Streptomyces aureofaciens EMBL ABB05105.1

Taxonomic identifier

1894 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	3277 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Ligand	Phosphopantetheine RuleBase RU000721
Molecular function	Transferase RuleBase RU000693
Gene Ontology (GO)
Biological_process	oxidation-reduction process Inferred from electronic annotation. Source: GOC
Molecular_function	oxidoreductase activity Inferred from electronic annotation. Source: InterPro phosphopantetheine binding Inferred from electronic annotation. Source: InterPro transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q30CR9 [UniParc]. Last modified December 6, 2005. Version 1. Checksum: 38D3D8C449DABB1D	FASTA	3,277	342,817
	10 20 30 40 50 60 MATPNEKVVE ALRASLKETE LLRQQNNALR AASSEPVAIV GMGCRFPGGV VSPEGLWEVV 70 80 90 100 110 120 LSGADVISEF PTDRGWDVEG LYDPDPDRPG KTYGRRGGFV DAVADFDAGF FGISPREALA 130 140 150 160 170 180 MDPQQRLLLE TSWEAFERAG IDPATLRGSR TGVFAGVMYH DYASRLREVP GHLEGLMGTG 190 200 210 220 230 240 NATSVIAGRL SYTFGLEGPS VSVDTACSSS LVALHLAVQA LRAGECEMAL AGGVTVMATP 250 260 270 280 290 300 EAFINFSRQR GLAADGRCKA FGAGADGTGW AEGAGMLLVE RLSDAQRLGH PILAVVRGSA 310 320 330 340 350 360 VNQDGASNGL TAPNGPAQQR VIRQALATAR LEAGQVDVVE AHGTGTSLGD PIEAQALMET 370 380 390 400 410 420 YGQERPAERP LWLGSLKSNI GHAQAAAGVG GVIKMVMALR EGVLPRTLHA DEPSPHIDWT 430 440 450 460 470 480 AGAVRLLTEQ SAWPDTQRPR RAAVSSFGFS GTNAHVIIEQ APDPAHPADT ADTNPGDGSV 490 500 510 520 530 540 VPWVISGASP QALRAQAEQL RSYIAERPGL RPADVAFSLA TTRSVLEHRA VVVGADHDDL 550 560 570 580 590 600 LDGLGELSLT GPVVEGMSAF LFTGQGAQRV GMGRELYDTF PAFRNALDKV CAVLDPLLPR 610 620 630 640 650 660 PSREVMWDED PEALSRTEFT QPTLFAIEVA LFRLLESWGI HPDAVAGHSI GEIAAAHVTG 670 680 690 700 710 720 VLSLTDACVL VAARGRLMQA LPHDGVMIAI QATEDEVLPL LEKVTGQADI AAVNAPEAVV 730 740 750 760 770 780 ISGAETEVEH VAGILTAQGR RVKRLTVSHA FHSPLMDPIL KDFQTVVEGL SFHQPSLPFV 790 800 810 820 830 840 STVTGTVAGA EITEPAYWVR HVRQTVRFAD GLRTLHELGV RKFIEIGPDA ILTGLVEQTL 850 860 870 880 890 900 DTQAVPVLRR DRDEVRAAVE AAGGFFTRGG SVDWPALLAG GRRVDLPTYA FQHERYWLEA 910 920 930 940 950 960 PVSVGDVAAV GLSAARHPLL GGAITLADRS GVLLTGRLSL ATHAWLADHA VHSTVLIPGT 970 980 990 1000 1010 1020 ALVELALRAG EEVGCDTVEE LTLQAPLVLP ATGARAVQVQ IVVGEPDARN LRPVDVYARV 1030 1040 1050 1060 1070 1080 EDDTGEAPWT CQATGLLAPG TGAPEEATDF AVWPPRDAEP VDIGGFYDAM ADRGYDYGPV 1090 1100 1110 1120 1130 1140 FRGLRSAWRR GDEVFAEIAL PEEAAGAARE FGVHPALLDS ALHAATAATD EHGDVTRVPF 1150 1160 1170 1180 1190 1200 SWRRVALYAA GATALRVHLT SAGETLTLRA ADTEGQLVAS VESLALREVS PEQLAVADDP 1210 1220 1230 1240 1250 1260 DSLFEVEWVS AADGGSTEAG TASWAVLGDS PLAEGGPVFA DVEALVASSQ DLPGTVVLEC 1270 1280 1290 1300 1310 1320 PAVEGAPVPD AVRDRLTGVL SVLQQWVADE RLASSRLVVV TRGAVAASAN EPADVRVAPV 1330 1340 1350 1360 1370 1380 WGLVCAAQAE HPGRFVLADL PVGAGARELS AGLACDEPQW AIRDGAVRVP RLVRAQPAVS 1390 1400 1410 1420 1430 1440 GVPAFGNGPV LVTGATGALG KLVARHLVSV HGVRELVLLS RRGLAADGMD TLRDELTHQG 1450 1460 1470 1480 1490 1500 ASVEVLACDA ADRDALAQVL DGRELTAVIH AAGVLDDGVL EALDASRLDT VLRPKMDAAW 1510 1520 1530 1540 1550 1560 NLHELTRHLD LTAFVLFSSA AGVLGNAGQA NYAAANVFLD ALAQTRRTES LPGLSLAWGL 1570 1580 1590 1600 1610 1620 WADDSAMTAG LTEADVRRLS RSGAGALSAD EGLALLDTAA MAVHHGLLIP VRLDLAALRT 1630 1640 1650 1660 1670 1680 ANAAPERVPQ ILRGLLPTPA RSRRRAAGAA TGTAADGGEL ASTLAPLDAP ARAAHVLDLI 1690 1700 1710 1720 1730 1740 RSAVASVLGH ASPDAVEPEK SFRDLGFDSL TAVDLRNRLT ATTGLRLPAT LVFDYPTSAA 1750 1760 1770 1780 1790 1800 LAEHVMTQVV GEADRVTTLV PAEAGADDPI VIVGMSCRYP GDVMTPEDLW DLVLSGGDAV 1810 1820 1830 1840 1850 1860 SEFPSDRGWD LENVYHPDPD HPGTTYSREG GFLHRAAEFD AEFFGISPRE ALAMDPQQRL 1870 1880 1890 1900 1910 1920 LLETSWEAFE RAGIDPATLR GSRTGVFAGV MYHDYASRLR EVPGHMEGLL GTGTAASVVS 1930 1940 1950 1960 1970 1980 GRLSYTFGLE GPAVTVDTAC SSSLVALHLA VQALRAGECE MALAGGVTVM ATPGAFINFS 1990 2000 2010 2020 2030 2040 RHRGLSPDGR CKAFAAGADG TGWAEGAGML LVERLSDAER LGHRVLAVVR GSAVNQDGAS 2050 2060 2070 2080 2090 2100 NGLTAPNGPS QQRVIRQALA TAGLTPTDID AVEGHGTGTS LGDPIEVQAL QATYGQERPA 2110 2120 2130 2140 2150 2160 EHPLWLGSLK SNIGHAQAAA GVGGVIKMVM ALREGVLPRT LHADEPSPHI DWTAGNVRLL 2170 2180 2190 2200 2210 2220 TEQSTWPDTQ RPRRAAVSSF GFSGTNAHVI IEQAPDPAHP ADTADTNPGD ESVVPWVISG 2230 2240 2250 2260 2270 2280 ASPQALRAQA EQLRSYIAER PGLRPADVAF SLATTRGALE HRAVVVGTDL SELAEGLGAL 2290 2300 2310 2320 2330 2340 TQTATAVPGR TAFLFTGQGA QRVGMGRELY DTFPAFRKAL DEVCAVLDPL LPRPSREVMW 2350 2360 2370 2380 2390 2400 DEDPEALSRT EFTQPTLFAI EVALFRLLES WGIHPDAVAG HSIGEIAAAH VTGVLSLTDA 2410 2420 2430 2440 2450 2460 CVLVAARGRL MQALPHDGVM IAVQATEDEV LPLLEKVTGQ ADIAAVNAPE AVVVSGAETE 2470 2480 2490 2500 2510 2520 VEHVAGILTA QGRRVKRLTV SHAFHSPLMD PILKDFQTVV EGLSFRQPSL PFVSTVTGTV 2530 2540 2550 2560 2570 2580 AGAEITEPAY WVRHVRQTVR FADGLRTLHG LGVRKFIEIG PDAILTGLVE QNQTLDTQAV 2590 2600 2610 2620 2630 2640 PVLRRDRDEV RAAVEAVGRL HLAGIPVDWP AVLPGARRVE LPTYAFQHER YWLDPEELAA 2650 2660 2670 2680 2690 2700 AAEDTVAPSG TEVPDPDTRF WGAVADEDLG SLAALLGIDG EKGGAQDRAA VEAALPVLAS 2710 2720 2730 2740 2750 2760 WLGRRQAAAR VSHYRVGWTP VARRPDGTTA RLRGIWLLTI PARIGADDAL VTRLASALGG 2770 2780 2790 2800 2810 2820 AGADVRVVTV GDPGADSYDD LAAEVSSLTA DGGELAGVLS LLGLASADGP GDAREAAVGT 2830 2840 2850 2860 2870 2880 LALLRALSGS VASVPVWSLT SGAVSTGGSE RVSAPAQAVL WGLGRLLAED SDVRWAGVVD 2890 2900 2910 2920 2930 2940 VPAPCGDRVL RRLAEVLANP AEETEVAVRD AGVFARRLLR ATGAADGPAR PTALAPRGTL 2950 2960 2970 2980 2990 3000 LVSGGSDTWR DRVARRLLAS GAAHVLVATA PDEPEPASTP GSAVTGVSRV VCDVSDGPAL 3010 3020 3030 3040 3050 3060 AHLAASLPAG PDGRPLTGVV HAPPATASDG PLDKALDEVL GAGLPALAGV SSTAGPIALF 3070 3080 3090 3100 3110 3120 LAVDVDDLVG APGAGAVAAL AGWWEAAARV RTADRAPVRL IAADPDALDL AVLDRAMERA 3130 3140 3150 3160 3170 3180 DGLLVVTGRD WAQYAGTHAD TRGRRLLEGV PEARAVLAAA APAGDAGKSG LLAGVDGPES 3190 3200 3210 3220 3230 3240 LRRVLAAREA DHKLATLVEL VRGQVAVVLG HASADAVSAD GDFMDLGFAS LTAVEFGHRL 3250 3260 3270 SAITGLKLPT TLVYDHLNPV ELAEHLADEL ARELTAA

References

[1]

"Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin." Bihlmaier C., Welle E., Hofmann C., Welzel K., Vente A., Breitling E., Muller M., Glaser S., Bechthold A. Antimicrob. Agents Chemother. 50:2113-2121(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Tu117 EMBL ABB05105.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DQ176871 Genomic DNA. Translation: ABB05105.1.
3D structure databases
ProteinModelPortal	Q30CR9.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	1.10.1200.10. 2 hits. 3.40.366.10. 4 hits. 3.40.47.10. 4 hits. 3.40.50.720. 1 hit.
InterPro	IPR001227. Ac_transferase_dom. IPR009081. Acyl_carrier_prot-like. IPR014043. Acyl_transferase. IPR016035. Acyl_Trfase/lysoPLipase. IPR002198. DH_sc/Rdtase_SDR. IPR018201. Ketoacyl_synth_AS. IPR014031. Ketoacyl_synth_C. IPR014030. Ketoacyl_synth_N. IPR016036. Malonyl_transacylase_ACP-bd. IPR016040. NAD(P)-bd_dom. IPR020842. PKS/FAS_KR. IPR020801. PKS_acyl_transferase. IPR020841. PKS_Beta-ketoAc_synthase_dom. IPR020807. PKS_dehydratase. IPR013968. PKS_KR. IPR020806. PKS_PP-bd. IPR006162. PPantetheine_attach_site. IPR016039. Thiolase-like. IPR016038. Thiolase-like_subgr. [Graphical view]
Pfam	PF00698. Acyl_transf_1. 2 hits. PF00106. adh_short. 1 hit. PF00109. ketoacyl-synt. 2 hits. PF02801. Ketoacyl-synt_C. 2 hits. PF08659. KR. 1 hit. PF00550. PP-binding. 2 hits. [Graphical view]
SMART	SM00827. PKS_AT. 2 hits. SM00826. PKS_DH. 1 hit. SM00822. PKS_KR. 1 hit. SM00825. PKS_KS. 2 hits. SM00823. PKS_PP. 2 hits. [Graphical view]
SUPFAM	SSF47336. ACP_like. 2 hits. SSF52151. Acyl_Trfase/lysoPlipase. 2 hits. SSF55048. Malonyl_transacylase_ACP-bd. 2 hits. SSF53901. Thiolase-like. 2 hits.
PROSITE	PS50075. ACP_DOMAIN. 2 hits. PS00606. B_KETOACYL_SYNTHASE. 2 hits. PS00012. PHOSPHOPANTETHEINE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q30CR9_STRAU

Accession

Primary (citable) accession number: Q30CR9

Entry history

Integrated into UniProtKB/TrEMBL:	December 6, 2005
Last sequence update:	December 6, 2005
Last modified:	May 29, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)