Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

MHC class I antigen

Gene

MHCX1

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class I antigenImported
Submitted name:
MHC class I heavy chainImported
Gene namesi
Name:MHCX1Imported
Synonyms:Eqca-5Imported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei307 – 32923HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence analysisAdd
BLAST
Chaini21 – 342322Sequence analysisPRO_5005931720Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Structurei

3D structure databases

SMRiQ30488. Positions 21-296.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini205 – 29389Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotation
Contains Ig-like C1-type (immunoglobulin-like) domain.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOVERGENiHBG016709.
KOiK06751.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view]
PRINTSiPR01638. MHCCLASSI.
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF54452. SSF54452. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q30488-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPATFLLLLS GTLTLTETWA GSHSMRYFLT AVSRPGRGEP RFISVGYVDD
60 70 80 90 100
TQFVRFDSDA ASPRMEPRAP WMEQEGPEYW ERNTRTAKDN AQAFRVSLNN
110 120 130 140 150
LRGYYNQSEA GSHTLQRMYG CDVGPDGRLL RGYSQFAYDG AEYITLNEDL
160 170 180 190 200
RSWTAADAAA QISKRKKEEA GDAENDRAYL DGECVEWLLR YLENGKKMLQ
210 220 230 240 250
RVDPPKTHVT HHPISDHEVI LRCWALGFYP AEITLTWQRD GEDLTQDTEF
260 270 280 290 300
VETRPAGDGT FQKWAAVVVP SGEEQSYTCR VQHEGLPEPV TLRWEPPSQP
310 320 330 340
TIPSVDLIAG LVFLGAVVIV AVVAAAVICK RKRSGGKGGS YA
Length:342
Mass (Da):38,257
Last modified:November 1, 1996 - v1
Checksum:i29DFED203DB2A509
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ083411 Genomic DNA. Translation: AAZ83338.1.
X71809 mRNA. Translation: CAA50684.1.
PIRiS33355.
RefSeqiNP_001093236.1. NM_001099766.1.
UniGeneiEca.12878.

Genome annotation databases

GeneIDi100056391.
KEGGiecb:100056391.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ083411 Genomic DNA. Translation: AAZ83338.1.
X71809 mRNA. Translation: CAA50684.1.
PIRiS33355.
RefSeqiNP_001093236.1. NM_001099766.1.
UniGeneiEca.12878.

3D structure databases

SMRiQ30488. Positions 21-296.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100056391.
KEGGiecb:100056391.

Organism-specific databases

CTDi100056391.

Phylogenomic databases

HOVERGENiHBG016709.
KOiK06751.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view]
PRINTSiPR01638. MHCCLASSI.
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF54452. SSF54452. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "At least four MHC class I genes are transcribed in the horse: phylogenetic analysis suggests an unusual evolutionary history for the MHC in this species."
    Ellis S.A., Martin A.J., Holmes E.C., Morrison W.I.
    Eur. J. Immunogenet. 22:249-260(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 3Imported.
  2. "Genomic characterization of MHC class I genes of the horse."
    Tallmadge R.L., Lear T.L., Antczak D.F.
    Immunogenetics 57:763-774(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ30488_HORSE
AccessioniPrimary (citable) accession number: Q30488
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: June 8, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.