Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q30265

- Q30265_BOVIN

UniProt

Q30265 - Q30265_BOVIN

Protein
Submitted name:

BoLA-DR-alpha

Gene

BoLA-DRA

Organism
Bos taurus (Bovine)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 84 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Biological processi

    1. antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Source: UniProtKB-KW
    2. immune response Source: InterPro

    Keywords - Biological processi

    Immunity

    Enzyme and pathway databases

    ReactomeiREACT_202824. Translocation of ZAP-70 to Immunological synapse.
    REACT_205423. Downstream TCR signaling.
    REACT_211133. MHC class II antigen presentation.
    REACT_212961. Phosphorylation of CD3 and TCR zeta chains.
    REACT_213223. PD-1 signaling.
    REACT_218413. Generation of second messenger molecules.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    BoLA-DR-alphaImported
    Gene namesi
    Name:BoLA-DRAImported
    OrganismiBos taurus (Bovine)Imported
    Taxonomic identifieri9913 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. late endosome membrane Source: Ensembl
    3. lysosomal membrane Source: Ensembl
    4. MHC class II protein complex Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane, MHC IISAAS annotation

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – 238›238BoLa-DR-alphaImportedPRO_5000006465Add
    BLAST

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Structurei

    3D structure databases

    ProteinModelPortaliQ30265.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the MHC class II family.UniRule annotation
    Contains Ig-like C1-type (immunoglobulin-like) domain.SAAS annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    HOVERGENiHBG006862.
    InParanoidiQ30265.

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    3.10.320.10. 1 hit.
    InterProiIPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003006. Ig/MHC_CS.
    IPR003597. Ig_C1-set.
    IPR011162. MHC_I/II-like_Ag-recog.
    IPR014745. MHC_II_a/b_N.
    IPR001003. MHC_II_a_N.
    [Graphical view]
    PfamiPF07654. C1-set. 1 hit.
    PF00993. MHC_II_alpha. 1 hit.
    [Graphical view]
    SMARTiSM00407. IGc1. 1 hit.
    SM00920. MHC_II_alpha. 1 hit.
    [Graphical view]
    SUPFAMiSSF54452. SSF54452. 1 hit.
    PROSITEiPS50835. IG_LIKE. 1 hit.
    PS00290. IG_MHC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q30265-1 [UniParc]FASTAAdd to Basket

    « Hide

    LIGLQESWAI KENHVIIQAE FYLKPEESAE FMFDFDGDEI FHVDMGKKET    50
    VWRLPEFGHF ASFEAQGALA NMAVMKANLD IMIKRSNNTP NTNVPPEVTL 100
    LPNKPVELGE PNTLICFIDK FSPPVISVTW LRNGKPVTDG VSQTVFLPRN 150
    DHLFRKFHYL PFLPTTEDVY DCKVEHLGLN EPLLKHWEYE APAPLPETTE 200
    NAVCALGLIV ALVGIIAGTI FIIKGVRKAN TVERRGPL 238
    Length:238
    Mass (Da):26,781
    Last modified:November 1, 1996 - v1
    Checksum:i68F450C6B959EC77
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D37955 mRNA. Translation: BAA07172.1.
    UniGeneiBt.8552.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D37955 mRNA. Translation: BAA07172.1 .
    UniGenei Bt.8552.

    3D structure databases

    ProteinModelPortali Q30265.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG006862.
    InParanoidi Q30265.

    Enzyme and pathway databases

    Reactomei REACT_202824. Translocation of ZAP-70 to Immunological synapse.
    REACT_205423. Downstream TCR signaling.
    REACT_211133. MHC class II antigen presentation.
    REACT_212961. Phosphorylation of CD3 and TCR zeta chains.
    REACT_213223. PD-1 signaling.
    REACT_218413. Generation of second messenger molecules.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    3.10.320.10. 1 hit.
    InterProi IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003006. Ig/MHC_CS.
    IPR003597. Ig_C1-set.
    IPR011162. MHC_I/II-like_Ag-recog.
    IPR014745. MHC_II_a/b_N.
    IPR001003. MHC_II_a_N.
    [Graphical view ]
    Pfami PF07654. C1-set. 1 hit.
    PF00993. MHC_II_alpha. 1 hit.
    [Graphical view ]
    SMARTi SM00407. IGc1. 1 hit.
    SM00920. MHC_II_alpha. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54452. SSF54452. 1 hit.
    PROSITEi PS50835. IG_LIKE. 1 hit.
    PS00290. IG_MHC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning of cDNAs and the molecular evolution of a bovine MHC class II DRA gene."
      Aida Y., Kohda C., Morooka A., Nakai Y., Ogimoto K., Urao T., Asahina M.
      Biochem. Biophys. Res. Commun. 204:195-202(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Japanese BlackImported.
      Tissue: Tumor lymph nodeImported.

    Entry informationi

    Entry nameiQ30265_BOVIN
    AccessioniPrimary (citable) accession number: Q30265
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 1, 1996
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)