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Q2YZ12 (FENR_STAAB) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferredoxin--NADP reductase
Short name=FNR
Short name=Fd-NADP+ reductase
EC=1.18.1.2
Gene names
Ordered Locus Names:SAB2252c
OrganismStaphylococcus aureus (strain bovine RF122 / ET3-1) [Complete proteome] [HAMAP]
Taxonomic identifier273036 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length344 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP MF_01685

Subunit structure

Homodimer By similarity. HAMAP MF_01685

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
NADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionferredoxin-NADP+ reductase activity

Inferred from electronic annotation. Source: EC

flavin adenine dinucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 344344Ferredoxin--NADP reductase HAMAP MF_01685
PRO_0000364934

Sites

Binding site121FAD By similarity
Binding site311FAD By similarity
Binding site391FAD By similarity
Binding site431FAD By similarity
Binding site831FAD; via amide nitrogen and carbonyl oxygen By similarity
Binding site1181FAD; via amide nitrogen By similarity
Binding site2851FAD By similarity
Binding site3261FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2YZ12 [UniParc].

Last modified December 20, 2005. Version 1.
Checksum: 4F6FAB7EC65C3830

FASTA34438,188
        10         20         30         40         50         60 
MKDVTIIGGG PSGLYASFYA GLRDMSVRLI DVQSELGGKM RIYPEKIIWD IGGIAPKPCH 

        70         80         90        100        110        120 
EILKDTIKQG LYFKPEVHLN ERVVDIRKKA ERHFEVETEA GEIYTSKAVI IAIGAGIINP 

       130        140        150        160        170        180 
KQLDVKGVER YQLTNLHYVV QSYRRFKDKD VLISGGGNTA LDWAHDIAKI AKSVTVVYRK 

       190        200        210        220        230        240 
EDVTGHEAMK TLVTDLNVKL CPKTRIKYLV GNDDETHISE VVLEHVESGD THTVKFDDVI 

       250        260        270        280        290        300 
ISHGFDRCNT LLSETSSKLD MHDDCRVKGF GNTTTSIPGI YACGDIVYHD AKSHLIASAF 

       310        320        330        340 
SDGANAANLA KTYIQPDANA EGYVSSHHEV FKEANKTIVN KHLY

« Hide

References

[1]"Molecular correlates of host specialization in Staphylococcus aureus."
Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.
PLoS ONE 2:E1120-E1120(2007) [PubMed: 17971880] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: bovine RF122 / ET3-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AJ938182 Genomic DNA. Translation: CAI81941.1.
RefSeqYP_417709.1. NC_007622.1.

3D structure databases

ProteinModelPortalQ2YZ12.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2YZ12.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTAT00000011981; EBSTAP00000011638; EBSTAG00000011980.
GeneID3793887.
GenomeReviewsGene locus SAB2252c in contig AJ938182_GR.
KEGGsab:SAB2252c.
NMPDRfig|273036.3.peg.2190.
PATRIC19525551. VBIStaAur92441_2371.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0492.
GeneTreeEBGT00050000023768.
HOGENOMHBG669726.
OMAFNTSITK.
ProtClustDBCLSK885935.

Enzyme and pathway databases

BioCycSAUR273036:SAB2252C-MONOMER.

Family and domain databases

HAMAPMF_01685. FENR2.
[Tree]
InterProIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
KOK00384.
PANTHERPTHR22912:SF53. PTHR22912:SF53. 1 hit.
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
PR00469. PNDRDTASEII.
ProtoNetSearch...

Entry information

Entry nameFENR_STAAB
AccessionPrimary (citable) accession number: Q2YZ12
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: December 20, 2005
Last modified: January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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