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Q2YYT9 (Y2178_STAAB) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative 2-hydroxyacid dehydrogenase SAB2178

EC=1.1.1.-
Gene names
Ordered Locus Names:SAB2178
OrganismStaphylococcus aureus (strain bovine RF122 / ET3-1) [Complete proteome] [HAMAP]
Taxonomic identifier273036 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length317 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 317317Putative 2-hydroxyacid dehydrogenase SAB2178
PRO_0000312182

Regions

Nucleotide binding155 – 1562NAD By similarity
Nucleotide binding234 – 2363NAD By similarity
Nucleotide binding283 – 2864NAD By similarity

Sites

Active site2361 By similarity
Active site2651 By similarity
Active site2831Proton donor By similarity
Binding site2601NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2YYT9 [UniParc].

Last modified December 20, 2005. Version 1.
Checksum: 49D41FDFA2A10B07

FASTA31734,689
        10         20         30         40         50         60 
MEKVYVAGAI PEVGLKLLQE HFEVEMYEGK GLVDKDTLIK GVKNATALIS LLSTNVDKDV 

        70         80         90        100        110        120 
IDAGKDLKII ANYGAGFNNI DIEYAREKSI DVTNTPKAST NATADLTIGL VLAIARRIVE 

       130        140        150        160        170        180 
GDQLSRTTGF DGWAPLFFRG REVSGKTIGI IGLGEIGSAV ARRARAFDMD VLYTGPNRKE 

       190        200        210        220        230        240 
EKEREIGAKY VDLDTLLKNA DFITINAAYN PKMHHLIDTE QFKMMKSTAY LINASRGPIV 

       250        260        270        280        290        300 
HEQALVQALK DNEIEGAALD VYEFEPDITD DLKSLNNVVL TPHIGNATFE ARDMMSKIVA 

       310 
NAAISAVQGE KPQFVVN 

« Hide

References

[1]"Molecular correlates of host specialization in Staphylococcus aureus."
Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.
PLoS ONE 2:E1120-E1120(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: bovine RF122 / ET3-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ938182 Genomic DNA. Translation: CAI81867.1.
RefSeqYP_417635.1. NC_007622.1.

3D structure databases

ProteinModelPortalQ2YYT9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING273036.SAB2178.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAI81867; CAI81867; SAB2178.
GeneID3793607.
KEGGsab:SAB2178.
PATRIC19525397. VBIStaAur92441_2294.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1052.
HOGENOMHOG000136700.
OMARGPIMNE.
OrthoDBEOG6VXFC3.

Enzyme and pathway databases

BioCycSAUR273036:GJVS-2252-MONOMER.

Family and domain databases

Gene3D3.40.50.720. 2 hits.
InterProIPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR006140. D-isomer_2_OHA_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameY2178_STAAB
AccessionPrimary (citable) accession number: Q2YYT9
Entry history
Integrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: December 20, 2005
Last modified: May 14, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families