Q2YWX2 (Q2YWX2_STAAB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Enoyl-[acyl-carrier-protein] reductase [NADPH] PIRNR PIRNR000094
Short name=ENR PIRNR PIRNR000094
EC=1.3.1.10 PIRNR PIRNR000094

Gene names

Name:	fabI EMBL CAI80565.1
Ordered Locus Names:	SAB0877

Organism

Staphylococcus aureus (strain bovine RF122 / ET3-1) [Complete proteome] [HAMAP]

Taxonomic identifier

273036 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	256 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acyl-[acyl-carrier-protein] + NADP+ = trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADPH. PIRNR PIRNR000094
Pathway	Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000094
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. PIRNR PIRNR000094

Ontologies

Keywords
Biological process	Fatty acid biosynthesis PIRNR PIRNR000094 Lipid synthesis
Ligand	NAD PIRNR PIRNR000094
Molecular function	Oxidoreductase PIRNR PIRNR000094 EMBL CAI80565.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	enoyl-[acyl-carrier-protein] reductase (NADH) activity Inferred from electronic annotation. Source: InterPro enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	157	1	Proton acceptor By similarity PIRSR PIRSR000094-1

Sequences

	Sequence		Length	Mass (Da)
	Q2YWX2 [UniParc]. Last modified December 20, 2005. Version 1. Checksum: D6B79F3A42C75513	FASTA	256	27,982
	10 20 30 40 50 60 MLNLENKTYV IMGIANKRSI AFGVAKVLDQ LGAKLVFTYR KERSRKELEK LLEQLNQPEA 70 80 90 100 110 120 HLYQIDVQSD EEVINGFEQI GKDVGNIDGV YHSIAFANME DLRGRFSETS REGFLLAQDI 130 140 150 160 170 180 SSYSLTIVAH EAKKIMPEGG SIVATTYLGG EFAVQNYNVM GVAKASLEAN VKYLALDLGS 190 200 210 220 230 240 DNIRVNAISA GPIRTLSAKG VGGFNTILKE IEERAPLKRN VDQVEVGKTA AYLLSDLSSG 250 VTGENIHVDS GFHAIK

References

[1]	"Molecular correlates of host specialization in Staphylococcus aureus." Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V. PLoS ONE 2:E1120-E1120(2007) [PubMed: 17971880] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ938182 Genomic DNA. Translation: CAI80565.1.
RefSeq	YP_416364.1. NC_007622.1.
3D structure databases
ProteinModelPortal	Q2YWX2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2YWX2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000012285; EBSTAP00000011942; EBSTAG00000012284.
GeneID	3793362.
GenomeReviews	Gene locus SAB0877 in contig AJ938182_GR.
KEGG	sab:SAB0877.
NMPDR	fig|273036.3.peg.997.
PATRIC	19522569. VBIStaAur92441_0935.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0623.
GeneTree	EBGT00050000023865.
HOGENOM	HBG750976.
OMA	KKWDGLD.
PhylomeDB	Q2YWX2.
ProtClustDB	PRK08594.
Enzyme and pathway databases
BioCyc	SAUR273036:SAB0877-MONOMER.
Family and domain databases
InterPro	IPR002198. DH_sc/Rdtase_SDR. IPR014358. Enoyl-ACP_Rdtase_NADH. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00208.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PIRSF	PIRSF000094. Enoyl-ACP_rdct. 1 hit.
PRINTS	PR00081. GDHRDH.
ProtoNet	Search...

Entry information

Entry name

Q2YWX2_STAAB

Accession

Primary (citable) accession number: Q2YWX2

Entry history

Integrated into UniProtKB/TrEMBL:	December 20, 2005
Last sequence update:	December 20, 2005
Last modified:	December 14, 2011
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)