SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q2YWF3

- ALF1_STAAB

UniProt

Q2YWF3 - ALF1_STAAB

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Fructose-bisphosphate aldolase class 1

Gene
fda, SAB2479
Organism
Staphylococcus aureus (strain bovine RF122 / ET3-1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei175 – 1751Proton acceptor By similarity
Active sitei212 – 2121Schiff-base intermediate with dihydroxyacetone-P By similarity

GO - Molecular functioni

  1. fructose-bisphosphate aldolase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

Schiff base

Enzyme and pathway databases

BioCyciSAUR273036:GJVS-2552-MONOMER.
UniPathwayiUPA00109; UER00183.

Names & Taxonomyi

Protein namesi
Recommended name:
Fructose-bisphosphate aldolase class 1 (EC:4.1.2.13)
Alternative name(s):
Fructose-bisphosphate aldolase class I
Short name:
FBP aldolase
Gene namesi
Name:fda
Ordered Locus Names:SAB2479
OrganismiStaphylococcus aureus (strain bovine RF122 / ET3-1)
Taxonomic identifieri273036 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000001927: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 296296Fructose-bisphosphate aldolase class 1UniRule annotationPRO_1000045919Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi273036.SAB2479.

Structurei

3D structure databases

ProteinModelPortaliQ2YWF3.
SMRiQ2YWF3. Positions 1-294.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG3588.
HOGENOMiHOG000073502.
KOiK01623.
OMAiYTGDYLA.
OrthoDBiEOG6M6JJT.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00729. FBP_aldolase_1.
InterProiIPR013785. Aldolase_TIM.
IPR000741. FBA_I.
IPR023014. FBA_I_Gram+-type.
[Graphical view]
PfamiPF00274. Glycolytic. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2YWF3-1 [UniParc]FASTAAdd to Basket

« Hide

MNKEQLEKMK NGKGFIAALD QSGGSTPKAL KEYGINEDQY SNEDEMFQLV    50
HDMRTRVVTS PSFSPDKILG AILFEQTMDR EVEGKYTADY LADKGVVPFL 100
KVDKGLAEEQ NGVQLMKPID NLDSLLDRAN ERHIFGTKMR SNILELNEQG 150
IKDVVEQQFE VAKQIIAKGL VPIIEPEVNI NAKDKAEIEK VLKAELKKGL 200
DSLNADQLVM LKLTIPTEAN LYKDLAEHPN VVRIVVLSGG YSREKANELL 250
KDNAELIASF SRALASDLRA GQSKEEFDKA LGDAVESIYD ASVNKN 296
Length:296
Mass (Da):32,927
Last modified:December 20, 2005 - v1
Checksum:iCB103A2A63539181
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ938182 Genomic DNA. Translation: CAI82167.1.
RefSeqiWP_001031398.1. NC_007622.1.
YP_417926.1. NC_007622.1.

Genome annotation databases

EnsemblBacteriaiCAI82167; CAI82167; SAB2479.
GeneIDi3793365.
KEGGisab:SAB2479.
PATRICi19526029. VBIStaAur92441_2610.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ938182 Genomic DNA. Translation: CAI82167.1 .
RefSeqi WP_001031398.1. NC_007622.1.
YP_417926.1. NC_007622.1.

3D structure databases

ProteinModelPortali Q2YWF3.
SMRi Q2YWF3. Positions 1-294.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273036.SAB2479.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAI82167 ; CAI82167 ; SAB2479 .
GeneIDi 3793365.
KEGGi sab:SAB2479.
PATRICi 19526029. VBIStaAur92441_2610.

Phylogenomic databases

eggNOGi COG3588.
HOGENOMi HOG000073502.
KOi K01623.
OMAi YTGDYLA.
OrthoDBi EOG6M6JJT.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00183 .
BioCyci SAUR273036:GJVS-2552-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00729. FBP_aldolase_1.
InterProi IPR013785. Aldolase_TIM.
IPR000741. FBA_I.
IPR023014. FBA_I_Gram+-type.
[Graphical view ]
Pfami PF00274. Glycolytic. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular correlates of host specialization in Staphylococcus aureus."
    Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.
    PLoS ONE 2:E1120-E1120(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: bovine RF122 / ET3-1.

Entry informationi

Entry nameiALF1_STAAB
AccessioniPrimary (citable) accession number: Q2YWF3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 20, 2005
Last modified: September 3, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi