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Q2YVW7 (Q2YVW7_STAAB) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribose-phosphate pyrophosphokinase HAMAP-Rule MF_00583
Short name=RPPK HAMAP-Rule MF_00583
EC=2.7.6.1 HAMAP-Rule MF_00583
Alternative name(s):
Phosphoribosyl pyrophosphate synthase HAMAP-Rule MF_00583
Gene names
Name:prs HAMAP-Rule MF_00583
Ordered Locus Names:SAB0449
OrganismStaphylococcus aureus (strain bovine RF122 / ET3-1) [Complete proteome] [HAMAP] EMBL CAI80137.1
Taxonomic identifier273036 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Staphylococcus ›

Protein attributes

Sequence length321 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP-Rule MF_00583 RuleBase RU004325

Cofactor

Binds 1 magnesium ion per subunit By similarity. HAMAP-Rule MF_00583

Pathway

Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1. HAMAP-Rule MF_00583

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00583.

Sequence similarities

Belongs to the ribose-phosphate pyrophosphokinase family. HAMAP-Rule MF_00583 RuleBase RU004324

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region221 – 234145-phosphoribose 1-diphosphate binding By similarity HAMAP-Rule MF_00583

Sites

Metal binding1351Magnesium By similarity HAMAP-Rule MF_00583
Metal binding1371Magnesium By similarity HAMAP-Rule MF_00583
Metal binding1461Magnesium By similarity HAMAP-Rule MF_00583
Metal binding1501Magnesium By similarity HAMAP-Rule MF_00583

Sequences

Sequence LengthMass (Da)Tools
Q2YVW7 [UniParc].

Last modified December 20, 2005. Version 1.
Checksum: 70A955AA62C9415E

FASTA32135,284
        10         20         30         40         50         60 
MLNNEYKNSS LKIFSLKGNE ALAQEVADQV GIELGKCSVK RFSDGEIQIN IEESIRGCDV 

        70         80         90        100        110        120 
FIIQPTSYPV NLHLMELLIM IDACKRASAA TINIVVPYYG YARQDRKARS REPITAKLVA 

       130        140        150        160        170        180 
NLIETAGATR MIALDLHAPQ IQGFFDIPID HLMGVPILAK HFKDDPNINP EECVVVSPDH 

       190        200        210        220        230        240 
GGVTRARKLA DILKTPIAII DKRRPRPNVA EVMNIVGEIE GRTAIIIDDI IDTAGTITLA 

       250        260        270        280        290        300 
AQALKDKGAK EVYACCTHPV LSGPAKERIE NSAIKELIVT NSIHLDEDRK PSNTKELSVA 

       310        320 
GLIAQAIIRV YERESVSVLF D

« Hide

References

[1]"Molecular correlates of host specialization in Staphylococcus aureus."
Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.
PLoS ONE 2:E1120-E1120(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: bovine RF122 / ET3-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AJ938182 Genomic DNA. Translation: CAI80137.1.
RefSeqYP_415948.1. NC_007622.1.

3D structure databases

ProteinModelPortalQ2YVW7.
SMRQ2YVW7. Positions 10-320.
ModBaseSearch...

Protein-protein interaction databases

STRING273036.SAB0449.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAI80137; CAI80137; SAB0449.
GeneID3794038.
KEGGsab:SAB0449.
PATRIC19521647. VBIStaAur92441_0488.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0462.
HOGENOMHOG000210449.
KOK00948.
OMAYVQIQES.
ProtClustDBPRK01259.

Enzyme and pathway databases

BioCycSAUR273036:GJVS-455-MONOMER.
UniPathwayUPA00087; UER00172.

Family and domain databases

HAMAPMF_00583_B. RibP_PPkinase_B.
InterProIPR000842. PRib_PP_synth_CS.
IPR000836. PRibTrfase_dom.
IPR005946. Rib-P_diPkinase.
[Graphical view]
PfamPF00156. Pribosyltran. 1 hit.
[Graphical view]
TIGRFAMsTIGR01251. ribP_PPkin. 1 hit.
PROSITEPS00114. PRPP_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ2YVW7_STAAB
AccessionPrimary (citable) accession number: Q2YVW7
Entry history
Integrated into UniProtKB/TrEMBL: December 20, 2005
Last sequence update: December 20, 2005
Last modified: May 1, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info