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Q2YVT4 (SLE1_STAAB) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-acetylmuramoyl-L-alanine amidase sle1

EC=3.5.1.28
Gene names
Name:sle1
Synonyms:aaa
Ordered Locus Names:SAB0414
OrganismStaphylococcus aureus (strain bovine RF122 / ET3-1) [Complete proteome] [HAMAP]
Taxonomic identifier273036 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length335 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Peptidoglycan hydrolase involved in the splitting of the septum during cell division By similarity.

Catalytic activity

Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.

Subcellular location

Secreted By similarity. Cell surface By similarity.

Sequence similarities

Contains 3 LysM repeats.

Contains 1 peptidase C51 domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2525 Potential
Chain26 – 335310N-acetylmuramoyl-L-alanine amidase sle1
PRO_0000231621

Regions

Repeat29 – 7143LysM 1
Repeat93 – 13543LysM 2
Repeat160 – 20243LysM 3
Domain211 – 335125Peptidase C51

Sequences

Sequence LengthMass (Da)Tools
Q2YVT4 [UniParc].

Last modified December 20, 2005. Version 1.
Checksum: 4C132CC34205FFB3

FASTA33535,937
        10         20         30         40         50         60 
MQKKVIAAII GTSAISAVAA TQANAATTHT VKPGESVWAI SNKYGISIAK LKSLNNLTSN 

        70         80         90        100        110        120 
LIFPNQVLKV SGSSNSTSNS SRPSTNSGGG SYYTVQAGDS LSLIASKYGT TYQNIMRLNG 

       130        140        150        160        170        180 
LNNFFIYPGQ KLKVSGTASS SNAASNSSRP STNSGGGSYY TVQAGDSLSL IASKYGTTYQ 

       190        200        210        220        230        240 
KIMSLNGLNN FFIYPGQKLK VTGNATSSNS ASATTTNRGY NTPVFSHQNL YTWGQCTYHV 

       250        260        270        280        290        300 
FNRRAEIGKG ISTYWWNANN WDNAAAADGY TIDNRPTVGS IAQTDVGYYG HVMFVERVNN 

       310        320        330 
DGSILVSEMN YSAAPGILTY RTVPAYQVNN YRYIH 

« Hide

References

[1]"Molecular correlates of host specialization in Staphylococcus aureus."
Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.
PLoS ONE 2:E1120-E1120(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: bovine RF122 / ET3-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ938182 Genomic DNA. Translation: CAI80102.1.
RefSeqYP_415913.1. NC_007622.1.

3D structure databases

ProteinModelPortalQ2YVT4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING273036.SAB0414.

Protein family/group databases

CAZyCBM50. Carbohydrate-Binding Module Family 50.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAI80102; CAI80102; SAB0414.
GeneID3792711.
KEGGsab:SAB0414.
PATRIC19521569. VBIStaAur92441_0453.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3942.
HOGENOMHOG000279823.
OMAEMNYSAS.
OrthoDBEOG6GTZPF.

Enzyme and pathway databases

BioCycSAUR273036:GJVS-416-MONOMER.

Family and domain databases

Gene3D3.10.350.10. 3 hits.
InterProIPR007921. CHAP_dom.
IPR018392. LysM_dom.
[Graphical view]
PfamPF05257. CHAP. 1 hit.
PF01476. LysM. 3 hits.
[Graphical view]
SMARTSM00257. LysM. 3 hits.
[Graphical view]
SUPFAMSSF54106. SSF54106. 3 hits.
PROSITEPS50911. CHAP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSLE1_STAAB
AccessionPrimary (citable) accession number: Q2YVT4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: December 20, 2005
Last modified: May 14, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries