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Q2YUU9 (SODM2_STAAB) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Superoxide dismutase [Mn/Fe] 2

EC=1.15.1.1
Gene names
Name:sodM
Ordered Locus Names:SAB0072
OrganismStaphylococcus aureus (strain bovine RF122 / ET3-1) [Complete proteome] [HAMAP]
Taxonomic identifier273036 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length199 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems By similarity.

Catalytic activity

2 superoxide + 2 H+ = O2 + H2O2.

Cofactor

Binds 1 manganese or iron ion per subunit By similarity.

Subunit structure

Homodimer. Can also form a heterodimer with SodA By similarity.

Sequence similarities

Belongs to the iron/manganese superoxide dismutase family.

Ontologies

Keywords
   Biological processStress response
   LigandIron
Manganese
Metal-binding
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processresponse to stress

Inferred from electronic annotation. Source: UniProtKB-KW

superoxide metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

superoxide dismutase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 199199Superoxide dismutase [Mn/Fe] 2
PRO_0000293964

Sites

Metal binding271Manganese or iron By similarity
Metal binding811Manganese or iron By similarity
Metal binding1611Manganese or iron By similarity
Metal binding1651Manganese or iron By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2YUU9 [UniParc].

Last modified December 20, 2005. Version 1.
Checksum: 366B86F577A3C635

FASTA19923,040
        10         20         30         40         50         60 
MAFKLPNLPY AYDALEPYID QRTMEFHHDK HHNTYVTKLN ATVEGTELEH QSLADMIANL 

        70         80         90        100        110        120 
DKVPEAMRMS VRNNGGGHFN HSLFWEILSP NSEEKGGVID DIKAQWGTLD EFKNEFANKA 

       130        140        150        160        170        180 
TTLFGSGWTW LVVNNGKLEI VTTPNQDNPL TEGKTPILLF DVWEHAYYLK YQNKRPDYMT 

       190 
AFWNIVNWKK VDELYQAAK 

« Hide

References

[1]"Molecular correlates of host specialization in Staphylococcus aureus."
Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.
PLoS ONE 2:E1120-E1120(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: bovine RF122 / ET3-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ938182 Genomic DNA. Translation: CAI79760.1.
RefSeqYP_415587.1. NC_007622.1.

3D structure databases

ProteinModelPortalQ2YUU9.
SMRQ2YUU9. Positions 2-195.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING273036.SAB0072.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAI79760; CAI79760; SAB0072.
GeneID3793002.
KEGGsab:SAB0072.
PATRIC19520835. VBIStaAur92441_0086.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0605.
HOGENOMHOG000013583.
KOK04564.
OMADYVLERY.
OrthoDBEOG63NMNT.
ProtClustDBCLSK884424.

Enzyme and pathway databases

BioCycSAUR273036:GJVS-74-MONOMER.

Family and domain databases

InterProIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERPTHR11404. PTHR11404. 1 hit.
PfamPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFPIRSF000349. SODismutase. 1 hit.
PRINTSPR01703. MNSODISMTASE.
SUPFAMSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEPS00088. SOD_MN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSODM2_STAAB
AccessionPrimary (citable) accession number: Q2YUU9
Entry history
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: December 20, 2005
Last modified: November 13, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families