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Q2YUL3

- PTPB_STAAB

UniProt

Q2YUL3 - PTPB_STAAB

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Protein

Low molecular weight protein-tyrosine-phosphatase PtpB

Gene

ptpB

Organism
Staphylococcus aureus (strain bovine RF122 / ET3-1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Dephosphorylates the phosphotyrosine-containing proteins.By similarity

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei7 – 71NucleophileBy similarity
Active sitei13 – 131By similarity
Active sitei111 – 1111Proton donorBy similarity

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Enzyme and pathway databases

BioCyciSAUR273036:GJVS-2064-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Low molecular weight protein-tyrosine-phosphatase PtpB (EC:3.1.3.48)
Alternative name(s):
Phosphotyrosine phosphatase B
Short name:
PTPase B
Gene namesi
Name:ptpB
Ordered Locus Names:SAB1999c
OrganismiStaphylococcus aureus (strain bovine RF122 / ET3-1)
Taxonomic identifieri273036 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000001927: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 139139Low molecular weight protein-tyrosine-phosphatase PtpBPRO_0000300671Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi273036.SAB1999c.

Structurei

3D structure databases

ProteinModelPortaliQ2YUL3.
SMRiQ2YUL3. Positions 1-134.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0394.
HOGENOMiHOG000273091.
KOiK01104.
OMAiPMAMALL.
OrthoDBiEOG6MH5JB.

Family and domain databases

InterProiIPR023485. Ptyr_pPase_SF.
IPR000106. Tyr_phospatase/Ars_reductase.
IPR017867. Tyr_phospatase_low_mol_wt.
[Graphical view]
PANTHERiPTHR11717:SF14. PTHR11717:SF14. 1 hit.
PfamiPF01451. LMWPc. 1 hit.
[Graphical view]
PRINTSiPR00719. LMWPTPASE.
SMARTiSM00226. LMWPc. 1 hit.
[Graphical view]
SUPFAMiSSF52788. SSF52788. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2YUL3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKILFVCTGN TCRSPLAESI AKEVMPNHQF ESRGIFAVNN QGVSNYVEDL
60 70 80 90 100
VEEHHLAETT LSQQFTEADL KADIILTMSY SHKELIEAHF GLQNHVFTLH
110 120 130
EYVKEAGEVI DPYGGTKEMY VHTYEELVSL ILKLKDIIC
Length:139
Mass (Da):15,788
Last modified:December 20, 2005 - v1
Checksum:i63EB2C0E2A53EA5B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ938182 Genomic DNA. Translation: CAI81688.1.
RefSeqiYP_417457.1. NC_007622.1.

Genome annotation databases

EnsemblBacteriaiCAI81688; CAI81688; SAB1999c.
GeneIDi3792828.
KEGGisab:SAB1999c.
PATRICi19525003. VBIStaAur92441_2106.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ938182 Genomic DNA. Translation: CAI81688.1 .
RefSeqi YP_417457.1. NC_007622.1.

3D structure databases

ProteinModelPortali Q2YUL3.
SMRi Q2YUL3. Positions 1-134.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273036.SAB1999c.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAI81688 ; CAI81688 ; SAB1999c .
GeneIDi 3792828.
KEGGi sab:SAB1999c.
PATRICi 19525003. VBIStaAur92441_2106.

Phylogenomic databases

eggNOGi COG0394.
HOGENOMi HOG000273091.
KOi K01104.
OMAi PMAMALL.
OrthoDBi EOG6MH5JB.

Enzyme and pathway databases

BioCyci SAUR273036:GJVS-2064-MONOMER.

Family and domain databases

InterProi IPR023485. Ptyr_pPase_SF.
IPR000106. Tyr_phospatase/Ars_reductase.
IPR017867. Tyr_phospatase_low_mol_wt.
[Graphical view ]
PANTHERi PTHR11717:SF14. PTHR11717:SF14. 1 hit.
Pfami PF01451. LMWPc. 1 hit.
[Graphical view ]
PRINTSi PR00719. LMWPTPASE.
SMARTi SM00226. LMWPc. 1 hit.
[Graphical view ]
SUPFAMi SSF52788. SSF52788. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Molecular correlates of host specialization in Staphylococcus aureus."
    Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.
    PLoS ONE 2:E1120-E1120(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: bovine RF122 / ET3-1.

Entry informationi

Entry nameiPTPB_STAAB
AccessioniPrimary (citable) accession number: Q2YUL3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: December 20, 2005
Last modified: October 29, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3