Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q2YUI3 (Q2YUI3_STAAB) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase 2 HAMAP MF_01201
EC=5.1.1.1 HAMAP MF_01201
Gene names
Name:alr EMBL CAI81644.1
Synonyms:alr2 HAMAP MF_01201
Ordered Locus Names:SAB1955c
OrganismStaphylococcus aureus (strain bovine RF122 / ET3-1) [Complete proteome] [HAMAP]
Taxonomic identifier273036 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length382 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the D-alanine required for cell wall biosynthesis By similarity. HAMAP MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01201 RuleBase RU000608 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP MF_01201 SAAS SAAS009006 RuleBase RU004247

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site391Proton acceptor; specific for D-alanine By similarity HAMAP MF_01201
Active site2651Proton acceptor; specific for L-alanine By similarity HAMAP MF_01201

Amino acid modifications

Modified residue391N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01201

Sequences

Sequence LengthMass (Da)Tools
Q2YUI3 [UniParc].

Last modified December 20, 2005. Version 1.
Checksum: 071A2155CC15E305

FASTA38242,867
        10         20         30         40         50         60 
MSDKYYRSAY MNVDLNAVAS NFKVFSTLHP NKTVMAVVKA NAYGLGSVKV ARHLMENGAT 

        70         80         90        100        110        120 
FFAVATLDEA IELRMHGITA KILVLGVLPA KDIDKAIQHR VALTVPSKQW LKEAIKNISD 

       130        140        150        160        170        180 
EQEKKLWLHI KLDTGMGRLG IKDTKTYQEV IEIIQQYEQL VFEGVFTHFV CADEPGDMTT 

       190        200        210        220        230        240 
EQYQRFKDMV NEAIKPEYIH CQNSAGSLLM DCQFCNAIRP GISLYGYYPS EYVQQKVKVH 

       250        260        270        280        290        300 
LKPSVQLIAN VVQTKTLQAG ESVSYGATYT ATDPTTIALL PIGYADGYLR IMQGSFVNVN 

       310        320        330        340        350        360 
GHQCEVVGRV CMDQTIVKVP DQVKAGDSVI LIDNHRESPQ SVEVAAEKQH TINYEVLCNL 

       370        380 
SRRLPRIYHD GDQRFVTNEL LK

« Hide

References

[1]"Molecular correlates of host specialization in Staphylococcus aureus."
Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.
PLoS ONE 2:E1120-E1120(2007) [PubMed: 17971880] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AJ938182 Genomic DNA. Translation: CAI81644.1.
RefSeqYP_417414.1. NC_007622.1.

3D structure databases

ProteinModelPortalQ2YUI3.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2YUI3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTAT00000011877; EBSTAP00000011534; EBSTAG00000011876.
GeneID3794899.
GenomeReviewsGene locus SAB1955c in contig AJ938182_GR.
KEGGsab:SAB1955c.
NMPDRfig|273036.3.peg.1895.
PATRIC19524913. VBIStaAur92441_2061.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
GeneTreeEBGT00050000023673.
HOGENOMHBG712172.
OMANWQIKAL.
PhylomeDBQ2YUI3.
ProtClustDBCLSK885747.

Enzyme and pathway databases

BioCycSAUR273036:SAB1955C-MONOMER.

Family and domain databases

HAMAPMF_01201. Ala_racemase.
[Tree]
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
Gene3DG3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 1 hit.
KOK01775.
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. Alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ2YUI3_STAAB
AccessionPrimary (citable) accession number: Q2YUI3
Entry history
Integrated into UniProtKB/TrEMBL: December 20, 2005
Last sequence update: December 20, 2005
Last modified: January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info