Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q2YU46

- PTPA_STAAB

UniProt

Q2YU46 - PTPA_STAAB

Protein

Low molecular weight protein-tyrosine-phosphatase PtpA

Gene

ptpA

Organism
Staphylococcus aureus (strain bovine RF122 / ET3-1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 1 (20 Dec 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Dephosphorylates the phosphotyrosine-containing proteins.By similarity

    Catalytic activityi

    Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei8 – 81NucleophileBy similarity
    Active sitei14 – 141By similarity
    Active sitei120 – 1201Proton donorBy similarity

    GO - Molecular functioni

    1. protein tyrosine phosphatase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Enzyme and pathway databases

    BioCyciSAUR273036:GJVS-1872-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Low molecular weight protein-tyrosine-phosphatase PtpA (EC:3.1.3.48)
    Alternative name(s):
    Phosphotyrosine phosphatase A
    Short name:
    PTPase A
    Gene namesi
    Name:ptpA
    Ordered Locus Names:SAB1813
    OrganismiStaphylococcus aureus (strain bovine RF122 / ET3-1)
    Taxonomic identifieri273036 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000001927: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 154154Low molecular weight protein-tyrosine-phosphatase PtpAPRO_0000300657Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi273036.SAB1813.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2YU46.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0394.
    HOGENOMiHOG000273094.
    KOiK01104.
    OMAiICHGNIC.
    OrthoDBiEOG6MH5JB.

    Family and domain databases

    InterProiIPR023485. Ptyr_pPase_SF.
    IPR000106. Tyr_phospatase/Ars_reductase.
    IPR017867. Tyr_phospatase_low_mol_wt.
    [Graphical view]
    PANTHERiPTHR11717. PTHR11717. 1 hit.
    PfamiPF01451. LMWPc. 1 hit.
    [Graphical view]
    PRINTSiPR00719. LMWPTPASE.
    SMARTiSM00226. LMWPc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52788. SSF52788. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q2YU46-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVDVAFVCLG NICRSPMAEA IMRQRLKDRN IHDIKVHSRG TGSWNLGEPP    50
    HEGTQKILNK HNIPFDGMIS ELFEATDDFD YIVAMDQSNV DNIKFINPNL 100
    KGQLFKLLEF SNMEESDVPD PYYTNNFEGV YDMVLSSCDN LIDYIVKDAN 150
    LKEG 154
    Length:154
    Mass (Da):17,551
    Last modified:December 20, 2005 - v1
    Checksum:i67E81E1E9425A4FD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ938182 Genomic DNA. Translation: CAI81502.1.
    RefSeqiYP_417275.1. NC_007622.1.

    Genome annotation databases

    EnsemblBacteriaiCAI81502; CAI81502; SAB1813.
    GeneIDi3794216.
    KEGGisab:SAB1813.
    PATRICi19524613. VBIStaAur92441_1917.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ938182 Genomic DNA. Translation: CAI81502.1 .
    RefSeqi YP_417275.1. NC_007622.1.

    3D structure databases

    ProteinModelPortali Q2YU46.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 273036.SAB1813.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAI81502 ; CAI81502 ; SAB1813 .
    GeneIDi 3794216.
    KEGGi sab:SAB1813.
    PATRICi 19524613. VBIStaAur92441_1917.

    Phylogenomic databases

    eggNOGi COG0394.
    HOGENOMi HOG000273094.
    KOi K01104.
    OMAi ICHGNIC.
    OrthoDBi EOG6MH5JB.

    Enzyme and pathway databases

    BioCyci SAUR273036:GJVS-1872-MONOMER.

    Family and domain databases

    InterProi IPR023485. Ptyr_pPase_SF.
    IPR000106. Tyr_phospatase/Ars_reductase.
    IPR017867. Tyr_phospatase_low_mol_wt.
    [Graphical view ]
    PANTHERi PTHR11717. PTHR11717. 1 hit.
    Pfami PF01451. LMWPc. 1 hit.
    [Graphical view ]
    PRINTSi PR00719. LMWPTPASE.
    SMARTi SM00226. LMWPc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52788. SSF52788. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Molecular correlates of host specialization in Staphylococcus aureus."
      Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.
      PLoS ONE 2:E1120-E1120(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: bovine RF122 / ET3-1.

    Entry informationi

    Entry nameiPTPA_STAAB
    AccessioniPrimary (citable) accession number: Q2YU46
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: December 20, 2005
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3