Q2YRU7 (RECA_BRUA2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein RecA

Alternative name(s):
Recombinase A

Gene names

Name:	recA
Ordered Locus Names:	BAB1_1224

Organism

Brucella abortus (strain 2308) [Complete proteome] [HAMAP]

Taxonomic identifier

359391 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella abortus

Protein attributes

Sequence length	361 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage By similarity. HAMAP-Rule MF_00268
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the RecA family.

Ontologies

Keywords
Biological process	DNA damage DNA recombination DNA repair SOS response
Cellular component	Cytoplasm
Ligand	ATP-binding DNA-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA recombination Inferred from electronic annotation. Source: HAMAP DNA repair Inferred from electronic annotation. Source: HAMAP SOS response Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA-dependent ATPase activity Inferred from electronic annotation. Source: HAMAP damaged DNA binding Inferred from electronic annotation. Source: HAMAP single-stranded DNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 361	361	Protein RecA HAMAP-Rule MF_00268		PRO_1000047893
Regions
	Nucleotide binding	77 – 84	8	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2YRU7 [UniParc]. Last modified December 20, 2005. Version 1. Checksum: 6E15766D33E5756E	FASTA	361	38,735
	10 20 30 40 50 60 MSQNSLRLVE DNSVDKTKAL DAALSQIERA FGKGSIMRLG QNDQVVEIET VSTGSLSLDI 70 80 90 100 110 120 ALGVGGLPKG RIVEIYGPES SGKTTLALHT IAEAQKKGGI CAFVDAEHAL DPVYARKLGV 130 140 150 160 170 180 DLENLLISQP DTGEQALEIT DTLVRSGAID VLVVDSVAAL TPRAEIEGEM GDSLPGLQAR 190 200 210 220 230 240 LMSQALRKLT GSISRSNCMV IFINQIRMKI GVMFGSPETT TGGNALKFYA SVRLDIRRIG 250 260 270 280 290 300 SIKERDEVVG NQTRVKVVKN KLAPPFKQVE FDIMYGAGVS KVGELVDLGV KAGVVEKSGA 310 320 330 340 350 360 WFSYNSQRLG QGRENAKQYL KDNPEVAREI ETTLRQNAGL IAEQFLDDGG PEEDAAGAAE M

References

[1]

"Whole-genome analyses of speciation events in pathogenic Brucellae." Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A., Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E. Infect. Immun. 73:8353-8361(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 2308.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM040264 Genomic DNA. Translation: CAJ11180.1.
RefSeq	YP_414610.1. NC_007618.1.
3D structure databases
ProteinModelPortal	Q2YRU7.
SMR	Q2YRU7. Positions 15-336.
ModBase	Search...
Protein-protein interaction databases
STRING	359391.BAB1_1224.
Proteomic databases
PRIDE	Q2YRU7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAJ11180; CAJ11180; BAB1_1224.
GeneID	3788897.
KEGG	bmf:BAB1_1224.
PATRIC	17845405. VBIBruMel86222_1272.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0468.
HOGENOM	HOG000264120.
KO	K03553.
OMA	TRKGAWY.
ProtClustDB	PRK09354.
Enzyme and pathway databases
BioCyc	BMEL359391:GJOQ-1246-MONOMER.
Family and domain databases
Gene3D	3.30.250.10. 1 hit.
HAMAP	MF_00268. RecA.
InterPro	IPR003593. AAA+_ATPase. IPR013765. DNA_recomb/repair_RecA. IPR020584. DNA_recomb/repair_RecA_CS. IPR020588. DNA_recomb_RecA/RadB_ATP-bd. IPR023400. RecA_C. IPR020587. RecA_monomer-monomer_interface. [Graphical view]
PANTHER	PTHR22942:SF1. PTHR22942:SF1. 1 hit.
Pfam	PF00154. RecA. 1 hit. [Graphical view]
PRINTS	PR00142. RECA.
SMART	SM00382. AAA. 1 hit. [Graphical view]
SUPFAM	SSF54752. SSF54752. 1 hit.
TIGRFAMs	TIGR02012. tigrfam_recA. 1 hit.
PROSITE	PS00321. RECA_1. 1 hit. PS50162. RECA_2. 1 hit. PS50163. RECA_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RECA_BRUA2

Accession

Primary (citable) accession number: Q2YRU7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	December 20, 2005
Last modified:	May 1, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program