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Q2YRP9

- CDSA_BRUA2

UniProt

Q2YRP9 - CDSA_BRUA2

Protein

Phosphatidate cytidylyltransferase

Gene

cdsA

Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (20 Dec 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    CTP + phosphatidate = diphosphate + CDP-diacylglycerol.

    Pathwayi

    GO - Molecular functioni

    1. phosphatidate cytidylyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Nucleotidyltransferase, Transferase

    Keywords - Biological processi

    Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

    Enzyme and pathway databases

    BioCyciBABO359391:GKDV-1201-MONOMER.
    BMEL359391:GJOQ-1201-MONOMER.
    UniPathwayiUPA00557; UER00614.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphatidate cytidylyltransferase (EC:2.7.7.41)
    Alternative name(s):
    CDP-DAG synthase
    CDP-DG synthase
    CDP-diacylglycerol synthase
    Short name:
    CDS
    CDP-diglyceride pyrophosphorylase
    CDP-diglyceride synthase
    CTP:phosphatidate cytidylyltransferase
    Gene namesi
    Name:cdsA
    Ordered Locus Names:BAB1_1179
    OrganismiBrucella abortus (strain 2308)
    Taxonomic identifieri359391 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000002719: Chromosome I

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 270270Phosphatidate cytidylyltransferasePRO_0000090728Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi359391.BAB1_1179.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei19 – 3921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei53 – 7321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei76 – 9621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei101 – 12121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei126 – 14621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei183 – 20321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei248 – 26821HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the CDS family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0575.
    HOGENOMiHOG000006169.
    KOiK00981.
    OMAiGFILYEW.
    OrthoDBiEOG6TBHJT.

    Family and domain databases

    InterProiIPR000374. PC_trans.
    [Graphical view]
    PfamiPF01148. CTP_transf_1. 1 hit.
    [Graphical view]
    PROSITEiPS01315. CDS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2YRP9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSNLQTRIIT AIVLGTITLW LTWVGGVGFT LFSIAIGLAM FYEWTELSAT    50
    RQTAFSRLFG WAWLIVTGIL LILDRGALLT IGFLVAGCAI LLVTQWKSGR 100
    GWPAAGLFYA GFSALSLSLL RGDEPFGFTT IVFLFAVVWS TDITAYFNGR 150
    ALGGPKLAPR FSPNKTWSGA IGGAAAAVAG GLLVASLVAA PGGWGVPVLA 200
    LLLSIVSQIG DLAESWVKRQ FGAKDSGRLL PGHGGVLDRV DGLVAAAALL 250
    YLFGAIFAEP DVLSAIFFSF 270
    Length:270
    Mass (Da):28,448
    Last modified:December 20, 2005 - v1
    Checksum:i47F253043415FF06
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U51683 Genomic DNA. Translation: AAA96785.1.
    AM040264 Genomic DNA. Translation: CAJ11135.1.
    RefSeqiYP_414570.1. NC_007618.1.

    Genome annotation databases

    EnsemblBacteriaiCAJ11135; CAJ11135; BAB1_1179.
    GeneIDi3788651.
    KEGGibmf:BAB1_1179.
    PATRICi17845313. VBIBruMel86222_1226.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U51683 Genomic DNA. Translation: AAA96785.1 .
    AM040264 Genomic DNA. Translation: CAJ11135.1 .
    RefSeqi YP_414570.1. NC_007618.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 359391.BAB1_1179.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAJ11135 ; CAJ11135 ; BAB1_1179 .
    GeneIDi 3788651.
    KEGGi bmf:BAB1_1179.
    PATRICi 17845313. VBIBruMel86222_1226.

    Phylogenomic databases

    eggNOGi COG0575.
    HOGENOMi HOG000006169.
    KOi K00981.
    OMAi GFILYEW.
    OrthoDBi EOG6TBHJT.

    Enzyme and pathway databases

    UniPathwayi UPA00557 ; UER00614 .
    BioCyci BABO359391:GKDV-1201-MONOMER.
    BMEL359391:GJOQ-1201-MONOMER.

    Family and domain databases

    InterProi IPR000374. PC_trans.
    [Graphical view ]
    Pfami PF01148. CTP_transf_1. 1 hit.
    [Graphical view ]
    PROSITEi PS01315. CDS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Isolation and sequence of the group 1 outer membrane protein of Brucella abortus."
      Bearden S.W., Ficht T.A.
      Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 2308.

    Entry informationi

    Entry nameiCDSA_BRUA2
    AccessioniPrimary (citable) accession number: Q2YRP9
    Secondary accession number(s): Q57CY2, Q59173
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 7, 2006
    Last sequence update: December 20, 2005
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Brucella abortus strain 2308
      Brucella abortus (strain 2308): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3