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Q2YQY6

- COAA_BRUA2

UniProt

Q2YQY6 - COAA_BRUA2

Protein

Pantothenate kinase

Gene

coaA

Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (07 Feb 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate.UniRule annotation

    Pathwayi

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi100 – 1078ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. pantothenate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. coenzyme A biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Coenzyme A biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBABO359391:GKDV-2142-MONOMER.
    BMEL359391:GJOQ-2142-MONOMER.
    UniPathwayiUPA00241; UER00352.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Pantothenate kinaseUniRule annotation (EC:2.7.1.33UniRule annotation)
    Alternative name(s):
    Pantothenic acid kinaseUniRule annotation
    Gene namesi
    Name:coaAUniRule annotation
    Ordered Locus Names:BAB1_2088
    OrganismiBrucella abortus (strain 2308)
    Taxonomic identifieri359391 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000002719: Chromosome I

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 322322Pantothenate kinasePRO_1000043213Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi359391.BAB1_2088.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2YQY6.
    SMRiQ2YQY6. Positions 12-322.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the prokaryotic pantothenate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1072.
    HOGENOMiHOG000248571.
    KOiK00867.
    OMAiFNRSQWA.
    OrthoDBiEOG62C9GX.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00215. Pantothen_kinase_1.
    InterProiIPR027417. P-loop_NTPase.
    IPR004566. PanK_bact.
    IPR006083. PRK/URK.
    [Graphical view]
    PANTHERiPTHR10285:SF7. PTHR10285:SF7. 1 hit.
    PfamiPF00485. PRK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000545. Pantothenate_kin. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00554. panK_bact. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q2YQY6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MWEKVDQLTP SRYSPYRFFS AQEWAAFRAD TPLTLTYEEV KRLRSLGDPI    50
    DLDEVRRIYL SLSRLLYAHV EASQLLFRQR QQFLNMEESY KTPFIIGVAG 100
    SVAVGKSTMA RILKELLARW PSSPKVDLVT TDGFLYPNAV LREQNMMERK 150
    GFPESYDIGA VLRFLSAIKA GMSRVRAPLY SHLSYDVLPG EYQIVDKPDI 200
    LIFEGINVLQ VRDLPEDGKM VPFVSDFFDF SIYIDADPRL IHKWYIDRFM 250
    RLRETAFRDP QSFFHRYSQL SQEAARSIAE GLWQNINMKN LNENILPTRP 300
    RADLILRKGS DHLIEEVALR KI 322
    Length:322
    Mass (Da):37,495
    Last modified:February 7, 2006 - v1
    Checksum:iD3EFE627DD4C7D0B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM040264 Genomic DNA. Translation: CAJ12044.1.
    RefSeqiYP_415416.1. NC_007618.1.

    Genome annotation databases

    EnsemblBacteriaiCAJ12044; CAJ12044; BAB1_2088.
    GeneIDi3788656.
    KEGGibmf:BAB1_2088.
    PATRICi17847275. VBIBruMel86222_2173.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM040264 Genomic DNA. Translation: CAJ12044.1 .
    RefSeqi YP_415416.1. NC_007618.1.

    3D structure databases

    ProteinModelPortali Q2YQY6.
    SMRi Q2YQY6. Positions 12-322.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 359391.BAB1_2088.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAJ12044 ; CAJ12044 ; BAB1_2088 .
    GeneIDi 3788656.
    KEGGi bmf:BAB1_2088.
    PATRICi 17847275. VBIBruMel86222_2173.

    Phylogenomic databases

    eggNOGi COG1072.
    HOGENOMi HOG000248571.
    KOi K00867.
    OMAi FNRSQWA.
    OrthoDBi EOG62C9GX.

    Enzyme and pathway databases

    UniPathwayi UPA00241 ; UER00352 .
    BioCyci BABO359391:GKDV-2142-MONOMER.
    BMEL359391:GJOQ-2142-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00215. Pantothen_kinase_1.
    InterProi IPR027417. P-loop_NTPase.
    IPR004566. PanK_bact.
    IPR006083. PRK/URK.
    [Graphical view ]
    PANTHERi PTHR10285:SF7. PTHR10285:SF7. 1 hit.
    Pfami PF00485. PRK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000545. Pantothenate_kin. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00554. panK_bact. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 2308.

    Entry informationi

    Entry nameiCOAA_BRUA2
    AccessioniPrimary (citable) accession number: Q2YQY6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: February 7, 2006
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Brucella abortus strain 2308
      Brucella abortus (strain 2308): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3