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Q2YQW4

- TRPF_BRUA2

UniProt

Q2YQW4 - TRPF_BRUA2

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciBABO359391:GKDV-2167-MONOMER.
BMEL359391:GJOQ-2167-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
Short name:
PRAIUniRule annotation
Gene namesi
Name:trpFUniRule annotation
Ordered Locus Names:BAB1_2113
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 222222N-(5'-phosphoribosyl)anthranilate isomerasePRO_1000018585Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi359391.BAB1_2113.

Structurei

3D structure databases

ProteinModelPortaliQ2YQW4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiDILQLHG.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2YQW4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALDIKICGL KTPEAVAAAL DGGATHIGFI FFPKSPRHIT PDAAARLRAA
60 70 80 90 100
ATGRAVAVAV TVDADDEALD EIVKTVRPDM LQLHGGETPE RVRFLKERYN
110 120 130 140 150
LPVMKAFSIR EAGDLEAIAP YRGIADRFLF DAKPPKGSEL PGGNGISFDW
160 170 180 190 200
NLLAALDADI DYMLSGGLNA DNIAEALLKT GAPGIDISSG VECAPGEKDV
210 220
RLIENFFQAV ADANAQPFAR RA
Length:222
Mass (Da):23,614
Last modified:February 7, 2006 - v1
Checksum:i28E7AFA3258F5514
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040264 Genomic DNA. Translation: CAJ12069.1.
RefSeqiYP_415438.1. NC_007618.1.

Genome annotation databases

EnsemblBacteriaiCAJ12069; CAJ12069; BAB1_2113.
GeneIDi3789037.
KEGGibmf:BAB1_2113.
PATRICi17847325. VBIBruMel86222_2198.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM040264 Genomic DNA. Translation: CAJ12069.1 .
RefSeqi YP_415438.1. NC_007618.1.

3D structure databases

ProteinModelPortali Q2YQW4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 359391.BAB1_2113.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ12069 ; CAJ12069 ; BAB1_2113 .
GeneIDi 3789037.
KEGGi bmf:BAB1_2113.
PATRICi 17847325. VBIBruMel86222_2198.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi DILQLHG.
OrthoDBi EOG6N94DF.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci BABO359391:GKDV-2167-MONOMER.
BMEL359391:GJOQ-2167-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiTRPF_BRUA2
AccessioniPrimary (citable) accession number: Q2YQW4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 7, 2006
Last modified: October 1, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3