Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phenylalanine--tRNA ligase beta subunit

Gene

pheT

Organism
Brucella abortus (strain 2308)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per tetramer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi454MagnesiumUniRule annotation1
Metal bindingi460Magnesium; via carbonyl oxygenUniRule annotation1
Metal bindingi463MagnesiumUniRule annotation1
Metal bindingi464MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding
Biological processProtein biosynthesis
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Phenylalanine--tRNA ligase beta subunitUniRule annotation (EC:6.1.1.20UniRule annotation)
Alternative name(s):
Phenylalanyl-tRNA synthetase beta subunitUniRule annotation
Short name:
PheRSUniRule annotation
Gene namesi
Name:pheTUniRule annotation
Ordered Locus Names:BAB1_2127
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000002719 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002320481 – 804Phenylalanine--tRNA ligase beta subunitAdd BLAST804

Proteomic databases

PRIDEiQ2YQV4

Interactioni

Subunit structurei

Tetramer of two alpha and two beta subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ2YQV4
SMRiQ2YQV4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini38 – 148tRNA-bindingUniRule annotationAdd BLAST111
Domaini401 – 476B5UniRule annotationAdd BLAST76
Domaini710 – 803FDX-ACBUniRule annotationAdd BLAST94

Sequence similaritiesi

Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000292085
KOiK01890
OMAiLTPNRSD

Family and domain databases

CDDicd02796 tRNA_bind_bactPheRS, 1 hit
Gene3Di3.30.70.380, 1 hit
3.50.40.10, 1 hit
HAMAPiMF_00283 Phe_tRNA_synth_beta1, 1 hit
InterProiView protein in InterPro
IPR005146 B3/B4_tRNA-bd
IPR009061 DNA-bd_dom_put_sf
IPR005121 Fdx_antiC-bd
IPR036690 Fdx_antiC-bd_sf
IPR012340 NA-bd_OB-fold
IPR004532 Phe-tRNA-ligase_IIc_bsu
IPR020825 Phe-tRNA_synthase_B3/B4
IPR002547 tRNA-bd_dom
IPR033714 tRNA_bind_bactPheRS
IPR005147 tRNA_synthase_B5-dom
PfamiView protein in Pfam
PF03483 B3_4, 1 hit
PF03484 B5, 1 hit
PF03147 FDX-ACB, 1 hit
PF01588 tRNA_bind, 1 hit
SMARTiView protein in SMART
SM00873 B3_4, 1 hit
SM00874 B5, 1 hit
SM00896 FDX-ACB, 1 hit
SUPFAMiSSF46955 SSF46955, 1 hit
SSF50249 SSF50249, 1 hit
SSF54991 SSF54991, 1 hit
TIGRFAMsiTIGR00472 pheT_bact, 1 hit
PROSITEiView protein in PROSITE
PS51483 B5, 1 hit
PS51447 FDX_ACB, 1 hit
PS50886 TRBD, 1 hit

Sequencei

Sequence statusi: Complete.

Q2YQV4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFTLSWLKD HLETDATLDE IVEKLTDIGL EVESVDDRAA FRAFTIARVL
60 70 80 90 100
TATRHPDADK LQVLSVDTGD GKPVQVVCGA PNARAGLVGV LGRPGDYVPG
110 120 130 140 150
LDVTLSVGKI RGVESFGMMC SERELELSDE HNGIIDLAEN APVGTSFAAY
160 170 180 190 200
MGLDDPIIEI GLTPNRADCT GIRGIARDLA AAGLGTLKNT LPDAVKGEGE
210 220 230 240 250
TPVKVILDQD AGNPFCTGFA LRMVKGVKNG PSPKWMQQRL KAIGLRPINA
260 270 280 290 300
LVDITNYVTF DQGRPLHVFD AAKVKGNLTV RTARDGETIL ALDQREYKLN
310 320 330 340 350
AGMYVIADEN GPESIAGIMG GEHSGCDENT VDVLIESALW DPRMIASTGR
360 370 380 390 400
ELGIVTDARY RFERGVDPEM MVPGAEIATK LVLELCGGQP TVLDVVGYKP
410 420 430 440 450
HTARVIDFPV TEVKRLTGLD VSYEDAFDIL KRLGFGVEGD GKTIRATVPS
460 470 480 490 500
WRGDVEGKAD LVEEVMRIHG INRIDPQPLP SHGAVNGRIL TTLQIRTRHA
510 520 530 540 550
RRMLASRGMM EAVTYSFISE AQAKAFGGGK PELKLANPIA ADMSDMRPSL
560 570 580 590 600
LPGLLAAAQR NADRGFDDIA LFEVSGIYEG DTPDKQRRVA GGVRRGTAKV
610 620 630 640 650
EGAGRFWAGN AAPVGVFDAK ADALAALEAA GAPVDRIQIE AGGPEWLHPG
660 670 680 690 700
RSGTLKLGPK VVLGTFGEFH PDTLEALDVS GALCGFEVYL DAIPEPKAKS
710 720 730 740 750
ARTKPALSLS LFQSLKRDYA FVVDAAVEAG NVVKAVSSAD KKLIVGVQVF
760 770 780 790 800
DIFTGASLGE GKKSIAVEVL LQPQDRTLTD EDLEALSKQI VASVAKQTGG

VLRG
Length:804
Mass (Da):85,838
Last modified:February 7, 2006 - v1
Checksum:iEABC1EC1A8230AA8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040264 Genomic DNA Translation: CAJ12083.1
RefSeqiWP_002965188.1, NZ_KN046823.1

Genome annotation databases

EnsemblBacteriaiCAJ12083; CAJ12083; BAB1_2127
KEGGibmf:BAB1_2127
PATRICifig|359391.11.peg.1359

Entry informationi

Entry nameiSYFB_BRUA2
AccessioniPrimary (citable) accession number: Q2YQV4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: February 7, 2006
Last modified: May 23, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health