Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q2YQR7

- IF2_BRUA2

UniProt

Q2YQR7 - IF2_BRUA2

Protein

Translation initiation factor IF-2

Gene

infB

Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (07 Feb 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi466 – 4738GTPUniRule annotation
    Nucleotide bindingi512 – 5165GTPUniRule annotation
    Nucleotide bindingi566 – 5694GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: UniProtKB-HAMAP
    2. GTP binding Source: UniProtKB-KW
    3. translation initiation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Initiation factor

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBABO359391:GKDV-2219-MONOMER.
    BMEL359391:GJOQ-2219-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Translation initiation factor IF-2UniRule annotation
    Gene namesi
    Name:infBUniRule annotation
    Ordered Locus Names:BAB1_2165
    OrganismiBrucella abortus (strain 2308)
    Taxonomic identifieri359391 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000002719: Chromosome I

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 959959Translation initiation factor IF-2PRO_0000228176Add
    BLAST

    Proteomic databases

    PRIDEiQ2YQR7.

    Interactioni

    Protein-protein interaction databases

    STRINGi359391.BAB1_2165.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2YQR7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini457 – 626170tr-type GAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni466 – 4738G1By similarity
    Regioni491 – 4955G2By similarity
    Regioni512 – 5154G3By similarity
    Regioni566 – 5694G4By similarity
    Regioni602 – 6043G5By similarity

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0532.
    HOGENOMiHOG000076907.
    KOiK02519.
    OMAiDATGKTR.
    OrthoDBiEOG67HJSV.

    Family and domain databases

    Gene3Di3.40.50.10050. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_00100_B. IF_2_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR013575. IF2_assoc_dom_bac.
    IPR006847. IF2_N.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR000178. TF_IF2_bacterial-like.
    IPR015760. TIF_IF2.
    IPR023115. TIF_IF2_dom3.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view]
    PANTHERiPTHR23115:SF41. PTHR23115:SF41. 1 hit.
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 2 hits.
    PF11987. IF-2. 1 hit.
    PF08364. IF2_assoc. 1 hit.
    PF04760. IF2_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF50447. SSF50447. 2 hits.
    SSF52156. SSF52156. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00487. IF-2. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS51722. G_TR_2. 1 hit.
    PS01176. IF2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2YQR7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSDKTNDDKT LSVNPKKTLT LKRPGVEQST VRQNFSHGRT KAVVVETKKR    50
    KFSRPDEKPE VEAAAAPKPA APAAAPQQAP ASAPVSASAA QASAPQPAPV 100
    KAPATKAPAA PSAPVTKPHV AQQRPVHQRP GGQQAQRPRP ADRSGMVLNT 150
    LSRSEMDARR RALEEAQIRE VEERARAVEE AKRRAEEDAR RAKEREESAR 200
    RQAEEEARLK AEAEARRKAE EEAAKRMPQP EARSERRDDA RPAPYGARPQ 250
    QAGRPQGGRP QPAGRPQQGS PRPAPIIADA APIAGKPLPQ SQLRKPGQSD 300
    DDDDRRSGAA RRGVAAKPEV RAPKVVKGED DRRRGKLTLT SNLEEEGRSR 350
    SLSAMRRRQE KFKRSQMQET REKISREVTI PETITLQELA QRMAERSVDI 400
    IKYLMKQGQM MKPGDVIDAD TAQLIAEEFG HTVKRVAESD VEEGIFDVAD 450
    NESAMVSRPP VVTIMGHVDH GKTSLLDAIR HANVVSGEAG GITQHIGAYQ 500
    VVQNGQKITF IDTPGHAAFT AMRARGAQAT DIAILVVAAD DSVMPQTIES 550
    INHAKAAGVP IIVAINKIDK PAADPQKVRT ALLQHEVFVE SMGGEVLDVE 600
    VSAKNKINLD KLLDAVLLQA EMLDLKADPD RTAEGVVIEA QLDRGRGSVA 650
    TVLIQKGTLH PGDILVAGSE WGRVRALVND RGEHVKEAGP AMPVEILGLQ 700
    GTPQAGDRFA VVANEAKARE IAEYRQRLAR DKAVARQSGA RGSLEQMMNQ 750
    LQVSGTKEFP LVIKGDVQGS IEAITNALDK LGTDEVRARI VHSGAGGITE 800
    SDVSLAEASN AAIIGFNVRA NKQARDSAEQ QGIEIRYYNI IYDLIDDVKA 850
    AMSGLLSPER RETFLGNAEI LEVFNITKVG KVAGCRVTEG KVERGAGVRL 900
    IRDNVVIHEG KLKTLKRFKD EVAEVPSGQE CGMAFENYDD IRAGDVIEAF 950
    RVEHVSRTL 959
    Length:959
    Mass (Da):104,141
    Last modified:February 7, 2006 - v1
    Checksum:i68B272FD63479FEE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM040264 Genomic DNA. Translation: CAJ12121.1.
    RefSeqiYP_415485.1. NC_007618.1.

    Genome annotation databases

    EnsemblBacteriaiCAJ12121; CAJ12121; BAB1_2165.
    GeneIDi3788765.
    KEGGibmf:BAB1_2165.
    PATRICi17847437. VBIBruMel86222_2254.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM040264 Genomic DNA. Translation: CAJ12121.1 .
    RefSeqi YP_415485.1. NC_007618.1.

    3D structure databases

    ProteinModelPortali Q2YQR7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 359391.BAB1_2165.

    Proteomic databases

    PRIDEi Q2YQR7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAJ12121 ; CAJ12121 ; BAB1_2165 .
    GeneIDi 3788765.
    KEGGi bmf:BAB1_2165.
    PATRICi 17847437. VBIBruMel86222_2254.

    Phylogenomic databases

    eggNOGi COG0532.
    HOGENOMi HOG000076907.
    KOi K02519.
    OMAi DATGKTR.
    OrthoDBi EOG67HJSV.

    Enzyme and pathway databases

    BioCyci BABO359391:GKDV-2219-MONOMER.
    BMEL359391:GJOQ-2219-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.10050. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_00100_B. IF_2_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR013575. IF2_assoc_dom_bac.
    IPR006847. IF2_N.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR000178. TF_IF2_bacterial-like.
    IPR015760. TIF_IF2.
    IPR023115. TIF_IF2_dom3.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view ]
    PANTHERi PTHR23115:SF41. PTHR23115:SF41. 1 hit.
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 2 hits.
    PF11987. IF-2. 1 hit.
    PF08364. IF2_assoc. 1 hit.
    PF04760. IF2_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50447. SSF50447. 2 hits.
    SSF52156. SSF52156. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00487. IF-2. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS51722. G_TR_2. 1 hit.
    PS01176. IF2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 2308.

    Entry informationi

    Entry nameiIF2_BRUA2
    AccessioniPrimary (citable) accession number: Q2YQR7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 21, 2006
    Last sequence update: February 7, 2006
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Brucella abortus strain 2308
      Brucella abortus (strain 2308): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3