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Q2YQR5

- TRUB_BRUA2

UniProt

Q2YQR5 - TRUB_BRUA2

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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Brucella abortus (strain 2308)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei49 – 491NucleophileUniRule annotation

GO - Molecular functioni

  1. pseudouridine synthase activity Source: UniProtKB-HAMAP
  2. RNA binding Source: InterPro

GO - Biological processi

  1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciBABO359391:GKDV-2221-MONOMER.
BMEL359391:GJOQ-2221-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:BAB1_2167
OrganismiBrucella abortus (strain 2308)
Taxonomic identifieri359391 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000002719: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 324324tRNA pseudouridine synthase BPRO_0000229344Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi359391.BAB1_2167.

Structurei

3D structure databases

ProteinModelPortaliQ2YQR5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0130.
HOGENOMiHOG000231225.
KOiK03177.
OMAiYELQFIR.
OrthoDBiEOG6358D3.

Family and domain databases

HAMAPiMF_01080. TruB_bact.
InterProiIPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR015240. tRNA_sdUridine_synth_fam1_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF09157. TruB-C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2YQR5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MARRGKKKGR PISGWVIFDK PKGMGSTEAV SKIKWLFSAE KAGHAGTLDP
60 70 80 90 100
LASGMLPIAL GEATKTVPYV MDGTKVYRFT VTWGEERSTD DLEGQPTKTS
110 120 130 140 150
DKRPSREEVE ALLPDYTGVI SQVPPQFSAI KIDGERAYDL AREGETVEIP
160 170 180 190 200
AREVEIDRLE IVGFPDADRT EFEVECSKGT YVRSLARDMG RDLGCYGHIS
210 220 230 240 250
DLRRVEVAPF TDEDMVTLAK LEAVWPPLPP KDEDGNVIEP APRRDFSALD
260 270 280 290 300
ALVIDTGAAL DCLPQVPLSD DQAQRVRLGN PVILRGRDAP LEADEACVTT
310 320
RGKLLAIGYI EHGQFKPKRV FTAG
Length:324
Mass (Da):35,595
Last modified:February 7, 2006 - v1
Checksum:i850AF77186777988
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040264 Genomic DNA. Translation: CAJ12123.1.
RefSeqiYP_415487.1. NC_007618.1.

Genome annotation databases

EnsemblBacteriaiCAJ12123; CAJ12123; BAB1_2167.
GeneIDi3788582.
KEGGibmf:BAB1_2167.
PATRICi17847441. VBIBruMel86222_2256.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM040264 Genomic DNA. Translation: CAJ12123.1 .
RefSeqi YP_415487.1. NC_007618.1.

3D structure databases

ProteinModelPortali Q2YQR5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 359391.BAB1_2167.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAJ12123 ; CAJ12123 ; BAB1_2167 .
GeneIDi 3788582.
KEGGi bmf:BAB1_2167.
PATRICi 17847441. VBIBruMel86222_2256.

Phylogenomic databases

eggNOGi COG0130.
HOGENOMi HOG000231225.
KOi K03177.
OMAi YELQFIR.
OrthoDBi EOG6358D3.

Enzyme and pathway databases

BioCyci BABO359391:GKDV-2221-MONOMER.
BMEL359391:GJOQ-2221-MONOMER.

Family and domain databases

HAMAPi MF_01080. TruB_bact.
InterProi IPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR015240. tRNA_sdUridine_synth_fam1_C.
[Graphical view ]
PANTHERi PTHR13767. PTHR13767. 1 hit.
Pfami PF09157. TruB-C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view ]
SUPFAMi SSF55120. SSF55120. 1 hit.
TIGRFAMsi TIGR00431. TruB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2308.

Entry informationi

Entry nameiTRUB_BRUA2
AccessioniPrimary (citable) accession number: Q2YQR5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: February 7, 2006
Last modified: October 1, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Brucella abortus strain 2308
    Brucella abortus (strain 2308): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3